Transdifferentiation of Clara Cell 10-kDa Protein Secreting Cells in Experimental Allergic Rhinitis

2011 ◽  
Vol 25 (3) ◽  
pp. 145-151 ◽  
Author(s):  
Yong-Hua Cui ◽  
Yuan-Yuan Wang ◽  
Zheng Liu
Keyword(s):  
Allergic Rhinitis ◽  
Clara Cell ◽  
Protein Secreting ◽  
Experimental Allergic

Correlation of Nasal Fluid Biomarkers and Symptoms in Patients with Persistent Allergic Rhinitis

2020 ◽  
Vol 129 (6) ◽  
pp. 542-547
Author(s):  
Su Il Kim ◽  
Oh Eun Kwon ◽  
Jung Min Park ◽  
Jeon Gang Doo ◽  
Seok Hyun Kim ◽  
...  
Keyword(s):  
Allergic Rhinitis ◽  
Inverse Correlation ◽  
Lavage Fluid ◽  
Nasal Symptom ◽  
Clara Cell ◽  
Cell Protein ◽  
Enzyme Linked Immunosorbent Assay ◽  
Prick Test ◽  
Persistent Allergic Rhinitis ◽  
Nasal Fluid

Objectives: This study investigated whether the biomarkers present in nasal fluid reflect the severity of symptoms in patients with persistent allergic rhinitis (PAR). Methods: We enrolled 29 PAR patients complaining of nasal symptoms and testing positive to skin prick test. Patients’ total nasal symptom score (TNSS) was measured and their nasal lavage fluid (NALF) was collected. The levels of biomarkers including Clara cell protein 16 (CC16), tryptase, and interleukin 5 (IL-5) in NALF were determined via enzyme-linked immunosorbent assay (ELISA). Results: PAR patients were classified into persistent mild and persistent moderate-to-severe groups according to the Allergic Rhinitis and its Impact on Asthma (ARIA) guidelines. The CC16 alone was significantly negatively correlated with TNSS ( P < .05). Further, the CC16 level was significantly lower in persistent moderate-to-severe group than persistent mild group of patients ( P < .05). Conclusions: The levels of CC16 alone among several NALF biomarkers showed an inverse correlation with symptoms of PAR patients.

scholarly journals Effects of Bifidobacterium bifidum G9-1 on Nasal Symptoms in a Guinea Pig Model of Experimental Allergic Rhinitis

2011 ◽  
Vol 30 (1) ◽  
pp. 1-7 ◽  
Author(s):  
Satoru Tsunemine ◽  
Yasuhiro Isa ◽  
Masaki Shimakawa ◽  
Hiroshi Ohno ◽  
Hideki Yamamura
Keyword(s):  
Allergic Rhinitis ◽  
Guinea Pig ◽  
Bifidobacterium Bifidum ◽  
Pig Model ◽  
Nasal Symptoms ◽  
Guinea Pig Model ◽  
Experimental Allergic

Is IL-5 suppression sufficient to control eosinophilic airway allery?: Studies of experimental allergic rhinitis in IL-5 deficient mice

2002 ◽  
Vol 109 (1) ◽  
pp. S255-S255
Author(s):  
Hiroko Saito ◽  
Lynn Crawford ◽  
Avram Denburg ◽  
Mark D Inman ◽  
Judah A Denburg
Keyword(s):  
Allergic Rhinitis ◽  
Deficient Mice ◽  
Experimental Allergic

scholarly journals Participation of Histamine H3 Receptors in Experimental Allergic Rhinitis of Mice

2008 ◽  
Vol 108 (2) ◽  
pp. 206-211 ◽  
Author(s):  
Emiko Yokota ◽  
Shoji Kuyama ◽  
Yukio Sugimoto ◽  
Masami Ogawa ◽  
Chiaki Kamei
Keyword(s):  
Allergic Rhinitis ◽  
Histamine H3 Receptors ◽  
H3 Receptors ◽  
Experimental Allergic ◽  
Histamine H3

scholarly journals Comparison of the efficacy of prednisolone, montelukast, and omalizumab in an experimental allergic rhinitis model

2014 ◽  
Vol 44 ◽  
pp. 439-447 ◽  
Author(s):  
Mete Kaan BOZKURT ◽  
Baykal TÜLEK ◽  
Banu BOZKURT ◽  
Nalan AKYÜREK ◽  
Mehmet ÖZ ◽  
...  
Keyword(s):  
Allergic Rhinitis ◽  
Experimental Allergic
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