Levamisole-Adulterated Cocaine Induced Skin Necrosis of Nose, Ears, and Extremities: Case Report

Levamisole is an immunomodulatory and antihelminthic drug, previously removed from the United States market, and now estimated to be present in the vast majority of cocaine distributed in the United States. Levamisole-adulterated cocaine (LAC) exposure can result in neutropenia, thrombocytopenia, and vasculitis with a predilection for subsites of the face. The objective of this review is to increase awareness among otolaryngologists of the manifestations of LAC exposure. We present the case of a 33-year-old woman with a history of cocaine use, consulted for purpuric, necrotic lesions of the nose, cheeks, and ears, with accompanying leukopenia, thrombocytopenia, and positive antineutrophil cytoplasmic antibodies (ANCA). The effects of levamisole are immune mediated, with antibodies directed against neutrophils causing neutropenia, and vasculitis caused by antibody deposition or secondary to induction of antiphospholipid antibodies causing thrombosis. LAC exposure can be differentiated from other similar appearing pathologies by evaluating serology for specific ANCA. The most important treatment is cessation of cocaine use, which most often results in complete resolution of symptoms. Awareness of the presentation, complications, and treatment of LAC exposure may be especially important for otolaryngologists, who may be one of the firsts to evaluate an affected patient.

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Belonging

Borders, Mobility and Belonging in the Era of Brexit and Trump ◽

10.1332/policypress/9781447347279.003.0004 ◽

2018 ◽

pp. 57-80

Author(s):

Mary Gilmartin ◽

Patricia Burke Wood ◽

Cian O’Callaghan

Keyword(s):

United States ◽

United Kingdom ◽

Common Sense ◽

The United States ◽

The United Kingdom ◽

The Face ◽

History Of

This chapter discusses the issue of belonging. It first focuses on citizenship, which is often described as formal belonging. While citizenship is regularly framed as ‘natural’ and ‘common sense’, it is argued that it is never fully stable or secure. This is shown in practice through the example of the United Kingdom and Ireland, specifically, how the Brexit vote has had knock-on consequences for how citizenship and belonging is being re-imagined in both places. This is contrasted with the practice of citizenship in the United States, where, despite effusive expressions of unity, articulations of belonging have a deep history of division and exclusion. It considers both the barriers to formal belonging experienced by undocumented residents of the United States and the ways in which citizens themselves struggle to achieve inclusion and equality in the face of increasingly explicit intolerance.

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Introduction to the Colorado River Negotiations

Winning Together ◽

10.7551/mitpress/9780262037136.003.0006 ◽

2017 ◽

Author(s):

Bruno Verdini Trejo

Keyword(s):

Climate Change ◽

United States ◽

River Basin ◽

Colorado River ◽

The United States ◽

River Delta ◽

Environmental Resources ◽

Key Players ◽

The Face ◽

History Of

Introduces the Colorado River case, presenting an overview of the chapters to follow, as well as providing context for analysis of the binational negotiations with a summary of the 2012 landmark Minute 319 agreement between the United States and Mexico. Outlines the key players, the decades-long history of protracted disputes over the waters of the river basin and the environmental resources of the Colorado River Delta, the increasing challenges in the face of extraordinary drought and climate change, and the mutual gains approach that underpinned the negotiations.

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“Design Thinking”: Defending Silicon Valley at the Apex of Global Labor Hierarchies

Catalyst Feminism Theory Technoscience ◽

10.28968/cftt.v4i1.29638 ◽

2018 ◽

Vol 4 (1) ◽

pp. 1-19 ◽

Cited By ~ 2

Author(s):

Lilly Irani

Keyword(s):

United States ◽

Design Thinking ◽

Business Schools ◽

Silicon Valley ◽

The United States ◽

Technical Expertise ◽

Public Debates ◽

The Face ◽

History Of ◽

The Subject

This paper examines the emergence of “design thinking” as a form of technical expertise. It demonstrates that “design thinking” articulates a racialized understanding of labor, judgment, and the subject and attempts to maintain whiteness at the apex of global hierarchies of labor.“Design thinking” is a form of expertise that poses design not as form giving, but as a form of empathic reason by which executives can plan products, services, and accumulation. Silicon Valley, business schools, and reformers promote it as a form of caring technical expertise by which some guide futures for others. The paper will examine the history of the concept of “design thinking” – a category forged by Silicon Valley designers in the face of mounting competitive pressures on design professions in the United States in the mid-2000s. By drawing on artifacts, documents, public debates about the design profession from this period, I will demonstrate how champions of “design thinking” responded to expanded availability of design labor globally by figuring Asians and machines as the creative subject's Other.

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Cuban Complaint of Aggression

International Organization ◽

10.1017/s0020818300010213 ◽

1960 ◽

Vol 14 (4) ◽

pp. 577-578 ◽

Cited By ~ 1

Keyword(s):

United States ◽

Security Council ◽

The United States ◽

Point Of View ◽

Cuban Government ◽

The Face ◽

History Of ◽

Cuban Sugar ◽

The Government ◽

Self Protection

From its 874th through its 876th meetings the Security Council considered the complaint of the government of Cuba that that country had been subjected by the government of the United States to “repeated threats, harassments, intrigues, reprisals and aggressive acts.” The discussion was opened by Mr. Raúl Roa, Cuban Minister for Foreign Affairs, who began by asserting that Cuba had been under no juridical obligation to bring its complaint to the Organization of American States (OAS) before submitting it to the Council. He then traced the history of United States hostility to the revolutionary government of Cuba, hostility based, in his opinion, on opposition to the Agrarian Reform instituted by that government and culminating in the recent drastic curtailment of the Cuban sugar quota. In his reply to Mr. Roa, Mr. Lodge (United States) assured the Cuban government that the United States had no aggressive purposes against Cuba, and deplored the removal of the controversy between the two nations from its rightful forum in OAS to the Security Council. He also indicated, after a summary of Cuban-United States relations during the preceding year and a half from the United States point of view, that the reduction of the Cuban sugar quota had been no act of economic aggression, but rather a justifiable measure of self-protection on the part of the United States to ensure its needed supply of sugar in the face of acts by the Cuban government which made this supply extremely insecure. In conclusion, Mr. Lodge stated his belief that someday, somehow, Cuba and the United States would again be friends.

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“Design Thinking”: Defending Silicon Valley at the Apex of Global Labor Hierarchies

Catalyst Feminism Theory Technoscience ◽

10.28968/cftt.v4i1.243 ◽

2018 ◽

Vol 4 (1) ◽

pp. 1-19 ◽

Cited By ~ 3

Author(s):

Lilly Irani

Keyword(s):

United States ◽

Design Thinking ◽

Business Schools ◽

Silicon Valley ◽

The United States ◽

Technical Expertise ◽

Public Debates ◽

The Face ◽

History Of ◽

The Subject

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What Meritocracy Means to its Winners: Admissions, Race, and Inequality at Elite Universities in the United States and Britain

Social Sciences ◽

10.3390/socsci7080131 ◽

2018 ◽

Vol 7 (8) ◽

pp. 131

Author(s):

Natasha Warikoo

Keyword(s):

United States ◽

Meaning Making ◽

The United States ◽

Symbolic Politics ◽

University Admissions ◽

University Of Oxford ◽

Brown University ◽

Self Interest ◽

The Face ◽

History Of

How do winners of processes of meritocracy make sense of those processes, especially in the face of forceful public critiques of their unequal outcomes? In this paper I analyze the meaning-making with respect to merit in university admissions of White, native-born undergraduates attending elite American and British universities. I find that United States students support the “calibration” of evaluations of merit, and emphasize evaluations of applicants’ contributions to the “collective merit” of their university cohorts. British students espouse a universalist, individualist understanding of merit. While conceptions of merit differed across national contexts, students in both reproduced the notions of merit espoused by their universities. I conclude that in spite of a long history of student protest on college campuses, rather than engagement with symbolic politics on liberal-identified campuses, self-interest in status legitimation dominates student perspectives, ultimately reproducing understandings of merit that will reproduce inequality. The paper draws upon 98 one-on-one in-depth interviews with White, native-born undergraduates attending Harvard University, Brown University, and University of Oxford.

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