MultiLevel Approach to Minimum Weight Deesign Including Buckling Constraints

AIAA Journal ◽  
1978 ◽  
Vol 16 (2) ◽  
pp. 97-104 ◽  
Author(s):  
L. A. Schmit ◽  
R. K. Ramanathan
1995 ◽  
Vol 117 (1) ◽  
pp. 206-209 ◽  
Author(s):  
G. M. Reddy ◽  
J. Cagan

This paper presents a technique for the generation and optimization of truss structure topologies based on the shape annealing algorithm. Feasible truss topologies are generated through a shape grammar in an optimally directed manner using simulated annealing for minimum weight, subject to stress and Euler buckling constraints.


1988 ◽  
Vol 60 (02) ◽  
pp. 188-192 ◽  
Author(s):  
F A Ofosu ◽  
F Fernandez ◽  
N Anvari ◽  
C Caranobe ◽  
F Dol ◽  
...  

SummaryA recent study (Fernandez et al., Thromb. Haemostas. 1987; 57: 286-93) demonstrated that when rabbits were injected with the minimum weight of a variety of glycosaminoglycans required to inhibit tissue factor-induced thrombus formation by —80%, exogenous thrombin was inactivated —twice as fast in the post-treatment plasmas as the pre-treatment plasmas. In this study, we investigated the relationship between inhibition of thrombus formation and the extent of thrombin inhibition ex vivo. We also investigated the relationship between inhibition of thrombus formation and inhibition of prothrombin activation ex vivo. Four sulfated polysaccharides (SPS) which influence coagulation in a variety of ways were used in this study. Unfractionated heparin and the fraction of heparin with high affinity to antithrombin III potentiate the antiproteinase activity of antithrombin III. Pentosan polysulfate potentiates the activity of heparin cofactor II. At less than 10 pg/ml of plasma, all three SPS also inhibit intrinsic prothrombin activation. The fourth agent, dermatan sulfate, potentiates the activity of heparin cofactor II but fails to inhibit intrinsic prothrombin activation even at concentrations which exceed 60 pg/ml of plasma. Inhibition of thrombus formation by each sulfated polysaccharides was linearly related to the extent of thrombin inhibition achieved ex vivo. These observations confirm the utility of catalysis of thrombin inhibition as an index for assessing antithrombotic potential of glycosaminoglycans and other sulfated polysaccharides in rabbits. With the exception of pentosan polysulfate, there was no clear relationship between inhibition of thrombus formation and inhibition of prothrombin activation ex vivo.


Alloy Digest ◽  
2020 ◽  
Vol 69 (11) ◽  

Abstract CarTech Ti-3Al-8V-6Cr-4Mo-4Zr, also known as Ti-3-8-6-4-4 and Beta C, is a metastable beta alloy used in the solution heat treated or solution heat treated and aged condition. It is appropriate for applications where very high strength, minimum weight, and corrosion resistance are important. Ti-3Al-8V-6Cr-4Mo-4Zr has gained in popularity among beta alloys because it is easier to melt and process, exhibiting low segregation, good workability, and good heat-treating properties. This datasheet provides information on composition, physical properties, elasticity, and tensile properties. It also includes information on corrosion resistance as well as forming, heat treating, machining, and joining. Filing Code: Ti-172. Producer or source: Carpenter Technology Corporation.


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