scholarly journals Perspectives on the Evolution of Mobile (mHealth) Technologies and Application to Rehabilitation

2015 ◽  
Vol 95 (3) ◽  
pp. 397-405 ◽  
Author(s):  
Brad E. Dicianno ◽  
Bambang Parmanto ◽  
Andrea D. Fairman ◽  
Theresa M. Crytzer ◽  
Daihua X. Yu ◽  
...  

Individuals with chronic conditions and disabilities who are vulnerable to secondary complications often require complex habilitative and rehabilitative services to prevent and treat these complications. This perspective article reviews the evolution of mHealth technologies and presents insights as to how this evolution informed our development of a novel mHealth system, iMHere (interactive mobile health and rehabilitation), and other technologies, including those used by the Veterans Administration. This article will explain the novel applications of mHealth for rehabilitation and specifically physical therapy. Perspectives on the roles of rehabilitation professionals in the delivery of health care using mHealth systems are included. Challenges to mHealth, including regulatory and funding issues, are discussed. This article also describes how mHealth can be used to improve patient satisfaction and delivery of care and to promote health and wellness.

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Leila Gholami ◽  
Vajihe Taghdiri Nooshabadi ◽  
Shiva Shahabi ◽  
Marzieh Jazayeri ◽  
Rana Tarzemany ◽  
...  

AbstractOral mesenchymal stem cells (MSCs) and their secretomes are considered important factors in the field of medical tissue engineering and cell free biotherapy due to their ease of access, differentiation potential, and successful therapeutic outcomes. Extracellular vesicles (EVs) and the conditioned medium (CM) from MSCs are gaining more attraction as an alternative to cell-based therapies due to the less ethical issues involved, and their easier acquisition, preservation, long term storage, sterilization, and packaging. Bone and periodontal regenerative ability of EVs and CM have been the focus of some recent studies. In this review, we looked through currently available literature regarding MSCs’ EVs or conditioned medium and their general characteristics, function, and regenerative potentials. We will also review the novel applications in regenerating bone and periodontal defects.


2001 ◽  
Vol 7 (2) ◽  
pp. 85-98 ◽  
Author(s):  
Evelyn P. Whitlock

We investigated HMO members' use of complementary and alternative medicine (CAM) providers outside the HMO in 1995-1996. A random 2% survey of Kaiser Permanente Northwest members addressed HMO service satisfaction, self-reported health status and behaviors, and HMO utilization. Among respondents, 15.7% (n = 380) used CAM providers (chiropractors, naturopaths, acupuncturists, others) in the prior 12 months, while 35% were ever users. Multivariate analysis found that those more likely to consult CAM providers were females, more educated, and more dissatisfied with the HMO. These results suggest that HMOs may wish to focus efforts to improve patient satisfaction among CAM service users.


2021 ◽  
Vol 5 (7) ◽  
pp. 181
Author(s):  
Dibyani Sahu ◽  
Harekrushna Sutar ◽  
Pragyan Senapati ◽  
Rabiranjan Murmu ◽  
Debashis Roy

Graphene has accomplished huge notoriety and interest from the universe of science considering its exceptional mechanical physical and thermal properties. Graphene is an allotrope of carbon having one atom thick size and planar sheets thickly stuffed in a lattice structure resembling a honeycomb structure. Numerous methods to prepare graphene have been created throughout a limited span of time. Due to its fascinating properties, it has found some extensive applications to a wide variety of fields. So, we believe there is a necessity to produce a document of the outstanding methods and some of the novel applications of graphene. This article centres around the strategies to orchestrate graphene and its applications in an attempt to sum up the advancements that has taken place in the research of graphene.


2018 ◽  
Vol 28 (5) ◽  
pp. 615-623
Author(s):  
Emily Warren ◽  
Ethel Nankya ◽  
Janet Seeley ◽  
Sarah Nakamanya ◽  
Gershim Asiki ◽  
...  

Author(s):  
С.М. Кравцов ◽  
Т.Л. Черноситова

Постановка задачи. Исследование билингвальных художественных произведений, созданных писателями-транслингвами, использующими несколько языков в своей творческой деятельности, является одной из наиболее актуальных проблем теории языка, в частности таких ее областей, как социолингвистика, стилистика, язык и социум, язык и культура. Подобные произведения, переведённые автором с одного языка на другой и адресованные представителям разных этнических сообществ, носят лингвосоциокультурный характер, который достигается писателем посредством создания интертекста, содержащего внутритекстовые вкрапления, основанные на аллегориях, реминисценциях, аллюзиях, цитациях и аппликациях. При этом аппликации принадлежит весьма важная роль в решении задачи формирования лингвокультурного диалога в билингвальном романе. Результаты исследования. Во франкоязычной версии романа Нэнси Хьюстон «Cantique des plaines», созданной в результате осуществленного ею самоперевода англоязычного романа «Plainsong», выявлено много текстовых аппликаций в виде фрагментов песен, с помощью которых автор формирует лингвокультурный диалог, а также создает не только смысловой, но и музыкальный фон произведения. Установлено, что с целью формирования лингвокультурного диалога в билингвальном романе аппликации в виде отрывков песен могут не совпадать в англоязычной и франкоязычной версиях. Данный эффект достигается во франкоязычной версии благодаря использованию цитат с расширением их посредством сочетаний слов; использованию лексем с более конкретным, точным значением, чем у их английских аналогов; использованию паронимов их английских аналогов; использованию дословного перевода песен с английского языка на французский; использованию включения в перевод на французский язык строфы из англоязычной песни с сохранением при переводе рифмы без искажения исходного смысла самой песни. Выводы. Результаты исследования позволяют сделать вывод о том, что аппликация песенных фрагментов в романе Нэнси Хьюстон «Cantique des plaines» / «Plainsong» является довольно продуктивным стилистическим приемом и имеет несколько видов реализации в зависимости от потребности автора в создании определенного смыслового, эмоционального и музыкального фона произведения. Благодаря широкому использованию и адекватному выбору писателем-транслингвом того или иного вида аппликации она служит эффективным способом формирования лингвокультурного диалога в билингвальном романе Нэнси Хьюстон «Cantique des plaines» / «Plainsong. Problem statement. The study of bilingual novels created by translingual writers who use several languages in their creative activities is one of the most urgent problems of language theory, specifically in such areas as sociolinguistics, stylistics, language and society, language and culture. Such works, translated by the author from one language to another and addressed to representatives of different ethnic communities, are of a linguistic and socio-cultural nature, which is achieved by the writer through the creation of an intertext containing intra-textual inclusions based on allegories, reminiscences, allusions, citations and applications. At the same time, the application plays a very important role in problem solving of forming a linguistic and cultural dialogue in a bilingual novel. The results of the study. In the French-language version of Nancy Huston's novel «Cantique des plaines», created as a result of self-translation of the English-language version of her novel «Plainsong», many text applications in the form of fragments of songs are revealed, by means of which the author forms a linguistic and cultural dialogue, and creates not only a semantic, but also a musical background of the novel. It is established that in order to form a linguistic and cultural dialogue in a bilingual novel, applications in the form of song fragments may not coincide in the English and French versions. This effect is achieved in the French-language version through the use of citations with their extension by word combinations; the use of lexemes with a more specific, accurate meaning than their English counterparts; the use of paronyms of their English counterparts; the use of a literal translation of songs from English into French; the use of including a stanza from an English-language song in the translation into French, while preserving the rhyme without distorting the original meaning of the song itself. Conclusion. The results of the analysis lead to the conclusion that the application of song fragments in Nancy Huston's novel «Cantique des plaines» / «Plainsong» is a rather productive stylistic technique and has several types of implementation, depending on the author's need to create a certain semantic, emotional and musical background of the work. Due to the wide use and adequate choice of a particular type of application by a translingual writer, it serves as an effective way of forming a linguistic and cultural dialogue in Nancy Huston's bilingual novel «Cantique des plaines» / «Plainsong». The results of the study indicate that it is relevant not only for the theory of language, but also for Romance and Germanic linguistics.


2021 ◽  
Vol 39 (15_suppl) ◽  
pp. 5050-5050
Author(s):  
Christopher G. C. A. Jackson ◽  
Yen-chuan Ou ◽  
Meng En ◽  
Tsu-Yi Chao ◽  
Noelyn Anne Hung ◽  
...  

5050 Background: Docetaxel has poor oral bioavailability in part due to extrusion by intestinal p-glycoprotein. To improve IV solubility, it is fomulated with the nonionic surfactant polysorbate 80, requiring steroid premedication to manage hypersensitivity type reactions. Oral administration has the potential to improve tolerability, reduce day-stay utilization and improve patient convenience and allows investigation of alternative dosing schedules. Oradoxel is a new combination of oral docetaxel capsules plus the novel gut-selective P-glycoprotein inhibitor encequidar (HM30181A). Methods: Patients with mPC receiving IV docetaxel were enrolled in 3 cohorts with a dose escalation schedule of Oradoxel 75 mg/m2 in Cohort 1, 150 mg/m2 in Cohort 2, 300mg/m2 in Cohort 3. Oradoxel was given 3 weeks before or after IV docetaxel treatment. Intensive PK samples were taken on days 1-5 for Oradoxel and days 1-4 for IV docetaxel. Dose limiting toxicity (DLT) or serious adverse events (SAE) were assessed per CTCAE v4.03. Results: 3 evaluable patients in each Cohort were studied. No DLT, MTD, or drug-related SAE were observed. PK parameters of Oradoxel vs IV docetaxel are summarized in the table below. Mean absolute bioavailability of Oradoxel was 15.9% (range 8-25%). PK became non linear at 300mg/m2. Conclusions: Oradoxel was well tolerated. Based on the results of this and related studies, Oradoxel 300mg/m2 in divided doses is being further evaluated in phase 2 studies. Clinical trial information: 12616000983404. [Table: see text]


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