scholarly journals Spectrum of hepatic encephalopathy admitted in a tertiary care center

2020 ◽  
Vol 72 ◽  
pp. 206-210
Author(s):  
Amit Soni ◽  
Shavi Nagpal ◽  
Amit Mittal
Keyword(s):  
Hepatic Encephalopathy ◽  
Hospital Mortality ◽  
Care Center ◽  
Tertiary Care ◽  
Abdominal Distension ◽  
Meld Score ◽  
Tertiary Care Center ◽  
Precipitating Factors ◽  
Cirrhotic Patients ◽  
Class C

Objectives: Few of the common symptoms for which cirrhotic patient seeks medical care are gastrointestinal bleed, abdominal distension (ascites), altered sensorium (hepatic encephalopathy [HE]), etc. This study was done to look at the spectrum of HE among cirrhotic patients admitted in a tertiary care center. Material and Methods: This hospital-based study was carried on 36 HE patients (with liver cirrhosis and age >18 years) admitted in the department of gastroenterology of a tertiary care center, between April 2019 and November 2019. Results: Constipation and infections were the two most frequent precipitating factors identified. Majority patients (77.8%) belonged to CTP Class C. In-hospital mortality was observed in seven patients. The OR was significant for infections and in-hospital mortality (OR – 28.80 and P < 0.05). A moderate positive correlation (Pearson’s correlation, r = 0.335) was seen between MELD score and in-hospital mortality among HE patients. Conclusion: A larger mass of HE patients belongs to CTP Class C. Constipation and infections are the two most common precipitating factors for HE. All HE patients who have concomitant infection and/or high MELD score should be managed on priority basis.

scholarly journals Hospital mortality in cirrhotic patients at a tertiary care center

2017 ◽  
Vol 82 (3) ◽  
pp. 203-209
Author(s):  
R. Zubieta-Rodríguez ◽  
J. Gómez-Correa ◽  
R. Rodríguez-Amaya ◽  
K.A. Ariza-Mejia ◽  
N.A. Toloza-Cuta
Keyword(s):  
Hospital Mortality ◽  
Care Center ◽  
Tertiary Care ◽  
Tertiary Care Center ◽  
Cirrhotic Patients

Clinical Profile, Precipitating Factors and Outcome of Hepatic Encephalopathy in Patients with Liver Cirrhosis

Med Phoenix ◽  
2021 ◽  
Vol 6 (1) ◽  
pp. 23-27
Author(s):  
Subash Bhattarai ◽  
Dipesh Karki
Keyword(s):  
Hepatic Encephalopathy ◽  
Clinical Profile ◽  
Decompensated Cirrhosis ◽  
Precipitating Factors ◽  
Early Management ◽  
Child Class ◽  
Grade Ii ◽  
Cirrhotic Patients ◽  
Class C ◽  
Upper Gastrointestinal

Introduction: Hepatic encephalopathy (HE) is characterized by reversible neuropsychological features and is observed with advanced and decompensated cirrhosis of the liver. Patients outcomes and survival depends on clinical presentation, identification of the precipitating factor, early management, and treatment of complications. This study aims to find out the clinical profile of cirrhotic patients with hepatic encephalopathy, their precipitating factors, and clinical outcomes in patients admitted at a tertiary care Teaching Hospital in Gandaki province, Nepal. Materials and Methods: An observational, cross-sectional, hospital-based prospective study comprising of 140 cirrhotic patients with encephalopathy was conducted over a study period of 18 months. Their clinical profile, precipitating factors, and outcomes during hospitalization including mortality were studied. The data analysis was done using SPSS version 20 and a P-value of ≤0.05 was considered significant. Results: Majority (36.5%) of the patients presented with Grade II HE. Upper gastrointestinal (GI) bleeding and spontaneous bacterial peritonitis were the most common precipitating factors. Inpatient mortality was 22.9%. The increased mortality rate was observed in patients with Child class C and with higher grading (Grade III and IV) of hepatic encephalopathy and in presence of more than two precipitating factors Conclusion: Most of the patients presented with Grade II HE. Upper gastrointestinal bleed and infections were the most common precipitating factors. Patients with Hepatic encephalopathy of Grades III and IV, those with CTP Child class C, and in presence of more than two precipitating factors have high mortality.

Abstract 15759: Utility of the Sofa Score to Risk Stratify Patients in the Cardiac Intensive Care Unit at a Tertiary Care Center

Circulation ◽  
2020 ◽  
Vol 142 (Suppl_3) ◽  
Author(s):  
Anika I Raja ◽  
Leonard Genovese ◽  
Ankit Vyas ◽  
PRAMITA BAGCHI ◽  
Palak Shah ◽  
...  
Keyword(s):  
Diabetes Mellitus ◽  
Intensive Care Unit ◽  
Intensive Care ◽  
Hospital Mortality ◽  
Sofa Score ◽  
Care Center ◽  
Tertiary Care ◽  
Retrospective Chart Review ◽  
Tertiary Care Center ◽  
Mortality Table

Introduction: The Sequential Organ Failure Assessment (SOFA) score predicts intensive care unit (ICU) mortality within a medical ICU population but utility of the SOFA score in the contemporary cardiac ICU (CICU) is unclear. Methods: Data from consecutive patients with primary cardiac (PC) and non-cardiac (PNC) disease admitted to the CICU at a tertiary care center from 1/1/19-2/28/19 and 10/1/19-11/30/19 were collected and analyzed by retrospective chart review, including demographics, comorbidities, primary reasons for admission, labs and SOFA score parameters. Patients were grouped into three categories based on their highest SOFA score within the first 24 hours of CICU admission: SOFA Score ≤ 6, 7-11 and ≥ 12. CICU and in-hospital mortality rates (adjusted for age, gender, race, and comorbidities) were compared using multivariate linear regression. Results: Of the 453 patients admitted to the CICU during the studied time period, 321 had PC diagnoses and 132 PNC diagnoses. The mean age was 63.5 and 59.6 ( p< 0.05) , 65.1% and 50.7% were male ( p< 0.05) , and 53.6% and 62.9% were white ( p=0.07) , and 70.4% and 56.8% had at least three or more comorbidities ( p<0.05) for the PC and PNC cohorts, respectively. The top three comorbidities were hypertension (70%), heart failure (39%), and diabetes mellitus (36%) for the PC group and hypertension (60%), diabetes mellitus (33%), and pulmonary disease (26%) for the PNC group, respectively. Increasing SOFA scores were associated with increased CICU and in-hospital mortality (Table) for patients with both PC and PNC diagnoses. Conclusion: Increased SOFA scores were associated with higher risk of CICU and in-hospital mortality. The SOFA score may be useful for risk stratification of CICU patients with both primary cardiac and non-cardiac diagnoses.

Mo1350 LOW IN-HOSPITAL MORTALITY AND ADVERSE EVENTS AFTER PERCUTANEOUS ENDOSCOPIC GASTROTOMY (PEG) IN A HIGH-VOLUME TERTIARY CARE CENTER

2019 ◽  
Vol 89 (6) ◽  
pp. AB503
Author(s):  
Akhil Munjal ◽  
Prithvi Patil ◽  
Eric D. Yoon ◽  
Matthew Meriwether ◽  
Sara Ali ◽  
...  
Keyword(s):  
Adverse Events ◽  
Hospital Mortality ◽  
Care Center ◽  
Tertiary Care ◽  
High Volume ◽  
Tertiary Care Center
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