scholarly journals Frontal swelling – An unusual presentation of sarcoidosis: A case report

2021 ◽  
Vol 0 ◽  
pp. 1-4
Author(s):  
Liya Poulose ◽  
Sheenu Mathew ◽  
Geethanjali Sahadevan ◽  
Seena Palakkal ◽  
Mary Vineetha

Subcutaneous sarcoidosis is a rare, cutaneous expression of systemic sarcoidosis. It is observed as asymptomatic firm, nodules covered by normal-appearing skin, principally on the extremities, which show the typical histopathology appearance of non-caseating granulomas localized to the subcutaneous tissue. It may be associated with the early benign, hilar lymphadenopathy of sarcoidosis or with the later stages of progressive sarcoidosis. Here, we report a case of subcutaneous sarcoidosis, which presented as an asymptomatic, forehead swelling with involvement of skull bone and lung. We report this case since subcutaneous sarcoidosis on the face with involvement of skull bone is a rarity.

2018 ◽  
Vol 128 (6) ◽  
pp. 1725-1730 ◽  
Author(s):  
Lefko T. Charalambous ◽  
Anirudh Penumaka ◽  
Jordan M. Komisarow ◽  
Amanda C. Hemmerich ◽  
Thomas J. Cummings ◽  
...  

Intracranial intravascular papillary endothelial hyperplasia (IPEH), also referred to as Masson’s tumor, is a condition that rarely occurs in the nervous system. IPEH most frequently occurs extracranially in the skin of the face, skull, neck, and trunk and can easily be mistaken clinically, radiologically, and histologically for angiosarcoma, organizing hematoma, or other vascular malformations. IPEH accounts for roughly 2% of all vascular tumors and is extremely rare intracranially, with only 23 reported cases compared with more than 300 cases of IPEH occurring in the skin and subcutaneous tissue. To date, it has never been reported to occur in the pineal region. The authors report the case of a patient with an IPEH in the pineal region who underwent complex resection and experienced reversal of neurological symptoms.


2019 ◽  
Vol 7 (4) ◽  
pp. 672-674
Author(s):  
Maha AlQusayer ◽  
Mei AlQusayer ◽  
Salim Alkeraye

2019 ◽  
Vol 41 (2) ◽  
pp. 296-299
Author(s):  
Julia Izadora da Silva Martins ◽  
Isabela Maria Bertoglio ◽  
Amanda Carolina Damasceno Zanuto Guerra ◽  
Mariana Espiga Maioli ◽  
Vinicius Daher Alvares Delfino

ABSTRACT Introduction: Purpura fulminans (PF) is a rapid progressive thrombotic disease in which hemorrhagic infarction of the skin and disseminated intravascular coagulation (DIC) occurs. It can potentially cause acute kidney injury (AKI). However, there is no description in the medical literature of renal histological findings of PF. Case report: A 20-year-old female patient, previously healthy, was admitted to the emergency department (ED) with odynophagia, fever, generalized myalgia and anuria, which evolved with the appearance of purpuric plaques on the face and limbs. She required dialysis on admission. Laboratorial tests showed anemia, leukocytosis, thrombocytopenia, and elevation of lactic dehydrogenase (LDH). The purpuric lesions became bullous with ruptures and then necrotic and erosive, reaching the dermis, subcutaneous tissue and musculature, until bone exposure. There was no improvement with initial antibiotic therapy aimed at the treatment of meningococcemia. Thrombotic microangiopathy (TMA) and PF were then suspected. The patient remained in daily dialysis, requiring plasmapheresis. After sustained improvement of the thrombocytopenia, she underwent renal biopsy, which was not compatible with TMA, characterizing possible PF. A complete recovery of the renal function was achieved and cutaneous sequels were treated with grafts. Conclusion: When thrombotic and hemorrhagic phenomena overlap, obtaining a renal biopsy can be difficult. However, in the presented case, the biopsy allowed the exclusion of AKI caused by TMA, presenting for the first time, histological findings compatible with PF.


2019 ◽  
Vol 6 (8) ◽  
pp. 2988
Author(s):  
Tharun Ganapathy Chitrambalam ◽  
Sidhu Sekhar ◽  
Koshy Mathew Panicker ◽  
Jeyakumar Sundaraj

Mycetoma is a chronic disease, which is endemic in tropical and subtropical countries. Mycetoma is a chronic subcutaneous infection caused by Actinomycetes or fungi. This infection results in a granulomatous inflammatory response in the deep dermis and subcutaneous tissue, which can extend to the underlying bone. Mycetoma is characterized by the formation of grains containing aggregates of the causative organisms that may be discharged onto the skin surface through multiple sinuses. Here we report an unusual presentation of eumycetoma in the thigh of a 41 year old male rural industrial worker hailing from South India.


2007 ◽  
Vol 45 (7) ◽  
pp. e2
Author(s):  
Syedda Abbas ◽  
P.S.G.F. Hardee ◽  
K. Piper ◽  
K. Bhatia

2017 ◽  
Vol 23 (1) ◽  
pp. 33-38
Author(s):  
Tatiana Adam ◽  
Laura Mazilu ◽  
L. Craciun ◽  
Adelina Anton ◽  
Dan Iliescu ◽  
...  

Abstract Sarcoidosis is a multisystem granulomatous disease with polymorphic manifestations, of unknown etiology, that can affect any organ in the body, but most commonly the lungs [1,2,3]. Extrapulmonary involvement is common, can occur in association with or in the absence of intrathoracic disease, and all organs can be involved, but it is rare to find an isolated extrapulmonary disease (less than 10% of patients) [3,4]. On occasion, the presentation of sarcoidosis may be atypical. We report a case of systemic sarcoidosis, with particular clinical data: extrathoracic onset with subdiaphragmatic lymph nodes, hepatomegaly and splenomegaly.


2020 ◽  
Vol 12 (3) ◽  
pp. 178-185
Author(s):  
Chaninan Kositkuljorn ◽  
Poonkiat Suchonwanit

Trichostasis spinulosa (TS) is a follicular disorder characterized by the retention of multiple vellus hairs in a hyperkeratotic dilated hair follicle. TS is considered as a common disorder; however, it is often underdiagnosed due to its asymptomatic nature. Although the condition frequently affects the face or extremities, the widespread distribution of TS over the entire body has been once reported in a patient with chronic renal failure. To emphasize the infrequent presentation of TS, we herein report a 57-year-old male with an unusual location of TS.


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