In vitro cytotoxicity investigations of chloroform extract of Anisomeles malabarica on vero and lung cancer [A-549] cell lines

2021 ◽  
Vol 16 (12) ◽  
pp. 95-99
Author(s):  
Duguluri Sajusha ◽  
Sivagnanam Selvakumar

The main objective of this study is to investigate the cytotoxic potential of chloroform extract of medicinal plant Anisomeles malabarica. Successive solvent extraction of Anisomeles malabarica in chloroform was done. The extracts were tested against normal cell lines (Vero) human lung cancer cell lines (A-549) using the thiazolyl blue tetrazolium bromide test (MTT) assay. The results of the present investigation revealed that the chloroform extract of Anisomeles malabarica shown anti-lung cancer activity. The evaluation of the toxicity of medicinal plants and their herbal preparations is essential to determine the applicability of the samples as pharmacological drugs. Further studies are necessary for more extensive pharmacological and toxicological evaluations.

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