Results of external quality assessment of cytogenetic investigations for 2020

2021 ◽  
pp. 48-50
Author(s):  
В.Г. Антоненко ◽  
Н.В. Шилова ◽  
Е.Н. Лукаш ◽  
Э.Р. Бабкеева ◽  
В.Н. Малахов
Keyword(s):  
Quality Assessment ◽  
Russian Federation ◽  
Interlaboratory Comparison ◽  
External Quality Assessment ◽  
Expert Assessment ◽  
External Quality ◽  
Cytogenetic Studies ◽  
The Russian Federation

Представлены результаты экспертной оценки качества цитогенетических исследований в лабораториях РФ в системе межлабораторных сличительных испытаний «ФСВОК» за 2020 г. The results of the expert assessment of the quality of cytogenetic studies in the laboratories of the Russian Federation in the system of interlaboratory comparison tests «FSVOK» for 2020 are presented.

FORMATION OF THE MODEL ASSESSMENT OF THE QUALITY OF PREPARATION OF MASTERS IN THE CONTEXT OF THE INSTITUTIONAL TRANSFORMATION OF HIGHER EDUCATION

2015 ◽  
Vol 10 (5) ◽  
pp. 214-226 ◽  
Author(s):  
Строева ◽  
Olesya Stroeva ◽  
Иващенко ◽  
Tatyana Ivashchenko
Keyword(s):  
Higher Education ◽  
Quality Assessment ◽  
Russian Federation ◽  
Assessment Model ◽  
Institutional Transformation ◽  
Model Assessment ◽  
Master Program ◽  
Foreign Experience ◽  
The Russian Federation

In the article the background of the quality assessment model of training Master students is examined. Based on the analysis of foreign experience academic models are structured formed as a result of several factors. The criteria of the formation of the institutional framework for transforming the system of higher education in general and Master training in particular. On the basis of the study the problems of functioning of Master Institute in the Russian Federation are systematized. Indicators of compliance of competencies of Master passport with the competencies of Master program are presented.

Assessing quality on the Sigma scale from proficiency testing and external quality assessment surveys

2015 ◽  
Vol 53 (10) ◽  
Author(s):  
James O. Westgard ◽  
Sten A. Westgard
Keyword(s):  
Quality Assessment ◽  
Proficiency Testing ◽  
External Quality Assessment ◽  
Objective Assessment ◽  
Analytical Quality ◽  
External Quality ◽  
Proficiency Assessment ◽  
Laboratory Examinations ◽  
Intended Use

AbstractThere is a need to assess the quality being achieved for laboratory examinations that are being utilized to support evidence-based clinical guidelines. Application of Six Sigma concepts and metrics can provide an objective assessment of the current analytical quality of different examination procedures.A “Sigma Proficiency Assessment Chart” can be constructed for data obtained from proficiency testing and external quality assessment surveys to evaluate the observed imprecision and bias of method subgroups and determine quality on the Sigma scale.Data for hemoglobin AAssessment of quality on the Sigma scale provides evidence of the analytical performance that is being achieved relative to requirements for intended use and should be useful for identifying and prioritizing improvements that are needed in the analytical quality of laboratory examinations. In spite of global and national standardization programs, bias is still a critical limitation of current HbA

scholarly journals The results of external quality assessment programme on urine leukocyte and erythrocyte counting in Poland

2020 ◽  
Vol 30 (2) ◽  
pp. 278-286
Author(s):  
Agnieszka Ćwiklińska ◽  
Barbara Kortas-Stempak ◽  
Maciej Jankowski ◽  
Gabriela Bednarczuk ◽  
Aleksandra Fijałkowska ◽  
...  
Keyword(s):  
Quality Assessment ◽  
External Quality Assessment ◽  
Particle Analysis ◽  
External Quality ◽  
Automated Method ◽  
Percentage Difference ◽  
Target Values ◽  
Important Diagnostic Tool ◽  
Manual Methods

Introduction: Urine particle analysis is an important diagnostic tool. The aim of this study was to evaluate the quality of urine leukocyte (WBC) and erythrocyte (RBC) counting results obtained with manual and automated methods in Polish laboratories participating in the international external quality assessment (EQA) programme. Materials and methods: 1400 WBC and RBC counting results were obtained from 183 laboratories in EQA surveys organised by Labquality (Helsinki, Finland) from 2017 to 2019. The between-laboratory coefficient of variation (CV), the percentage difference between the laboratories' results and target values (Q-score (%)), as well as modified Youden plots were analysed. Results: For automated method groups, the medians of inter-laboratory CVs varied from 14% to 33% for WBC counting and from 10% to 39% for RBC counting. For manual method groups, the medians of CV varied from 53% to 71% (WBC) and from 55% to 70% (RBC), and they were significantly higher, in comparison to CVs for most automated method groups (P < 0.001). The highest percentage of results outside the target limits (36%) and the highest range of Q-score (%) (from - 93% to 706%) were observed for laboratories which participated in the surveys for the first or second time. The percentage of deviating results and the ranges of Q-score decreased with an increased frequency of laboratories’ participation in the surveys. Conclusions: The quality of manual methods of urine WBC and RBC counting is unsatisfactory. There is an urgent need to take actions to improve laboratories’ performance and to increase harmonisation of the results.

Quality Assessment of Tumor Marker Determinations: A Proposal for a Supraregional Scheme

1994 ◽  
Vol 9 (1) ◽  
pp. 48-52
Author(s):  
A. Piffanelli ◽  
M. Giganti ◽  
P. Colamussi ◽  
C. Cittanti ◽  
D. Pelizzola ◽  
...  
Keyword(s):  
Quality Assessment ◽  
Tumor Marker ◽  
Tumor Markers ◽  
External Quality Assessment ◽  
Clinical Chemistry ◽  
External Quality ◽  
Realistic Information ◽  
Eqa Schemes

The use of tumor marker tests has increased progressively in the last decade concomitant with the advent of new monoclonal antibodies and their growing use in clinical oncology for various follow-up programs. External quality assessment (EQA) schemes widely adopted in clinical chemistry, have been extended in the last decade to immunoassays of hormones and tumor markers. EQA results can provide realistic information on the quality of the assays, performed under routine conditions. The goal of this article is to report the main results and discrepancies encountered so far in External Quality Assessment programs on tumor markers.

scholarly journals Thirteen Years of an International External Quality Assessment Scheme for Genotyping: Results and Recommendations

2016 ◽  
Vol 62 (8) ◽  
pp. 1084-1095 ◽  
Author(s):  
Verena Haselmann ◽  
Wolf J Geilenkeuser ◽  
Simona Helfert ◽  
Romy Eichner ◽  
Svetlana Hetjens ◽  
...  
Keyword(s):  
Genetic Testing ◽  
Quality Assessment ◽  
Error Rate ◽  
External Quality Assessment ◽  
Molecular Genetic ◽  
Genetic Diagnostics ◽  
External Quality ◽  
Sequence Variations ◽  
Therapeutic Decisions

Abstract BACKGROUND Suboptimal laboratory procedures resulting in genotyping errors, misdiagnosis, or incorrect reporting bear greatly on a patient's health management, therapeutic decisions made on their behalf, and ultimate outcome. Participation in external quality assessment (EQA) is a key element of quality assurance in molecular genetic diagnostics. Therefore, the Reference Institute for Bioanalytics has tried for 13 years to improve the quality of genetic testing by offering an EQA for different clinically relevant sequence variations. METHODS Within each of the biannual EQA schemes offered, up to 18 samples of lyophilized human genomic DNA were provided for up to 50 different molecular genetic tests. Laboratories were asked to use their routine procedures for genotyping. At least 2 expert peer assessors reviewed the final returns. Data from 2002 to 2014 were evaluated. RESULTS In total, 82 462 reported results from 812 characterized samples were evaluated. Globally, the number of participants increased each year along with the number of sequence variations offered. The error rate decreased significantly over the years with an overall error rate of 1.44%. Additionally, a decreased error rate for samples repeated over time was noted. Interestingly, the error rate showed a high difference depending on the locus analyzed and the method used. CONCLUSIONS Based on the evaluation of this long-term EQA scheme, various recommendations can be given to improve the quality of molecular genetic testing, such as the use of 2 different methods for genotyping. Furthermore, some methods are inappropriate for analysis of certain sequence variations.

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