LAPAROSCOPIC RADICAL TRACHELECTOMY WITH PELVIC LYMPHADENECTOMY – CASE SERIES OF 17 PATIENTS FROM A BRAZILIAN CANCER CENTER

2016 ◽  
Author(s):  
Georgia Cintra
Keyword(s):  
Case Series ◽  
Pelvic Lymphadenectomy ◽  
Cancer Center ◽  
Radical Trachelectomy

scholarly journals Extraperitoneal radical trachelectomy with pelvic lymphadenectomy

2019 ◽  
Vol 29 (4) ◽  
pp. 842-842
Author(s):  
Kotaro Shimura ◽  
Seiji Mabuchi
Keyword(s):  
Cervical Cancer ◽  
Surgical Approach ◽  
Uterine Cervix ◽  
Early Stage ◽  
Foley Catheter ◽  
Pelvic Lymphadenectomy ◽  
Radical Trachelectomy ◽  
Uterosacral Ligaments ◽  
Early Stage Cervical Cancer ◽  
Umbilical Ligament

Radical trachelectomy combined with pelvic lymphadenectomy has been used to treat patients with early-stage cervical cancer who wish to preserve their fertility. Vaginal, abdominal, laparoscopic, and robotic approaches have been employed during this procedure, but all cause peritoneal damage, which could result in periadnexal adhesion. As periadnexal adhesion can lead to female infertility due to restricted sweeping of the fimbria over the ovary, it is important to minimize peritoneal damage during the fertility-preserving surgery. Aiming to minimize peritoneal damage, we recently developed a new surgical approach. The techniques used are similar to those used for type III radical hysterectomy; however, all procedures are performed via the extraperitoneal approach.In this video article, we describe a step-by-step technique of this new fertility-preserving surgical procedure. Surgical procedures are as follows: (1) extraperitoneal pelvic lymphadenectomy, (2) excision of the vesicohypogastric fascia and median umbilical ligament, (3) bladder dissection from the peritoneum and identification of uterine cervix, (4) transection of the cardinal ligaments and vesicouterine ligaments, (5) transection of the vagina, (6) excision of the rectovaginal and uterosacral ligaments, (7) transection of the uterine cervix, (8) cervical cerclage and placement of a Foley catheter, (9) anastomosis of the uterine cervix, (10) suture of the median umbilical ligament and vesicohypogastric fascia. During these procedures, the uterine arteries, inferior hypogastric nerve, and pelvic splanchnic nerve were preserved. The advantages of this new surgical approach are first, peritoneal injuries can be completely avoided as the procedure is performed extraperitoneally, and second, it can be carried out using conventional low-cost instruments. In view of these features, we consider that this technique could be an ideal treatment option for selected women with early-stage cervical cancer. The oncological and reproductive outcomes of this new surgical approach need to be evaluated in future clinical studies.

Abdominal radical trachelectomy for invasive cervical cancer: A case series and literature review

2008 ◽  
Vol 111 (3) ◽  
pp. 555-560 ◽  
Author(s):  
Rene Pareja F. ◽  
Pedro T. Ramirez ◽  
Mauricio Borrero F. ◽  
Gonzalo Angel C.
Keyword(s):  
Cervical Cancer ◽  
Literature Review ◽  
Invasive Cervical Cancer ◽  
Case Series ◽  
Radical Trachelectomy

scholarly journals Plasmacytoid Urothelial Carcinoma of the Bladder: Case Report and Review of the Literature

2019 ◽  
Vol 28 (04) ◽  
pp. 333-337
Author(s):  
Ángela Molina Barrera ◽  
Andrea Vásquez Franco ◽  
Andrés Felipe Aristizábal ◽  
David Correa Galeano ◽  
Manuel Cabrales Hessen
Keyword(s):  
Case Report ◽  
Urothelial Carcinoma ◽  
Case Series ◽  
Pelvic Lymphadenectomy ◽  
Ultrasound Finding ◽  
Invasive Potential ◽  
Aggressive Approach ◽  
Urothelial Carcinomas ◽  
Histological Variant ◽  
Carcinoma Of The Bladder

Introduction Plasmacytoid urothelial carcinoma (PUC) of the bladder is a rare histological variant, accounting for 1 to 3% of the invasive urothelial carcinomas, and it is typically aggressive. So far, it has not been well characterized, and the literature is based on reports and case series. Case Report A 70-year-old male patient presenting with 4 months of constitutional and urinary symptoms, with an ultrasound finding of bilateral hydronephrosis and diffuse thickening of the bladder walls. In the cystoscopy, trigone of infiltrated appearance, a biopsy wass performed, whose immunohistochemistry revealed a PUC. The abdominopelvic image showed an infiltrative lesion that compromised the muscle of the bladder and extended to the perivesical fat, without adequate plane of cleavage with the prostate and a single hypogastric adenopathy suspected of malignancy. It was classified as cT3b vs cT4aN1M0 (chest computed tomography [CT] negative for malignancy), and the patient was submitted to a radical cystoprostatectomy, extended pelvic lymphadenectomy and non-continent urinary diversion with ileal conduit. The pathology revealed a diffuse PUC with prostatic stromal involvement and 22 of 39 lymph nodes positive for malignancy. Finally, the patient presented a series of postoperative complications and died. Conclusion Plasmacytoid urothelial carcinoma of the bladder is a rare entity, characterized by high aggressiveness, an advanced stage at the time of diagnosis, and a poor prognosis. Currently, an aggressive approach is recommended due to its high invasive potential.

scholarly journals EPID-05. A CASE SERIES OF METASTATIC GLIOBLASTOMA AT MEMORIAL SLOAN KETTERING CANCER CENTER

2018 ◽  
Vol 20 (suppl_6) ◽  
pp. vi80-vi81
Author(s):  
Evan Noch ◽  
Sameer Sait ◽  
Alexandra Miller
Keyword(s):  
Case Series ◽  
Cancer Center

Clinical findings and outcomes from MRI staging of breast cancers in women.

2012 ◽  
Vol 30 (15_suppl) ◽  
pp. 1124-1124
Author(s):  
Akshara Raghavendra ◽  
Charite Nicolette Ricker ◽  
Lingyun Ji ◽  
Terry Church ◽  
Sujie Tang ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Risk Factors ◽  
Underserved Populations ◽  
Preoperative Staging ◽  
Case Series ◽  
Comprehensive Cancer Center ◽  
Cancer Center ◽  
Minority Population ◽  
Breast Cancers ◽  
Mri Staging

1124 Background: For patients diagnosed with breast cancer, case series have shown that staging MRI can detect occult breast cancers in 1-10% of cases. Prevalence and risk factors in underserved populations remain unclear. Methods: We performed a retrospective analysis of all patients, newly diagnosed, with breast cancer who had a preoperative staging MRI seen at Norris Comprehensive Cancer Center and LAC +USC, that cares for an underserved and minority population, from 2006 to 2011. Demographic, clinicopathologic and imaging data were obtained through a review of electronic records. Non index lesions were defined as those not known to be malignant, not presenting with clinical, mammographic or ultrasound findings, in a different quadrant and given an MRI BIRADS score of 4 or 5. Results: A total of 718 patients were analyzed and 148 patients (21%) had a total of 187 non index lesions; 63% were ipsilateral, 26% contralateral and 11% bilateral. As initial evaluation of non-index ipsilateral lesions, 71 (38%) had biopsy, 24 (13%) had excision and 34 (18%) had mastectomy. For contralateral non-index lesions, 41 (22%) had contralateral biopsy, 6 (3%) had excision and 11(6%) had mastectomy. Among all non index lesions, 111 (59%) were benign, 14 (7%) DCIS and 62 (33%) invasive cancer. Occult ipsilateral cancer was detected in 50 (6.9%) of patients and contralateral in 10 (1.4%) and bilateral in 6 (0.8%). Conclusions: The occult cancer detection rate with staging MRI was in this 9.2% of this diverse population. No clear risk factors were identified, with detailed factors, including BRCA status to be updated and reanalyzed. [Table: see text]

Treatment of patients with metastatic renal cell carcinoma (RCC) and end-stage renal disease (ESRD) with targeted therapy (TT): A case series.

2012 ◽  
Vol 30 (5_suppl) ◽  
pp. 453-453 ◽  
Author(s):  
Amber Flaherty ◽  
Marc Ryan Matrana ◽  
Bradley J. Atkinson ◽  
Nizar M. Tannir
Keyword(s):  
Adverse Events ◽  
Clear Cell ◽  
Case Series ◽  
Median Number ◽  
Cancer Center ◽  
Limited Data ◽  
Inclusion Criteria ◽  
Md Anderson ◽  
Stage Renal Disease ◽  
End Stage

453 Background: Studies have shown that RCC is more prevalent in patients with ESRD, and RCC outcomes in patients with ESRD differ from those of the general RCC population. There is limited data regarding the use of TT in patients with metastatic RCC (mRCC) who are maintained on dialysis for ESRD. Methods: We retrospectively reviewed records of patients with mRCC who were seen at UT MD Anderson Cancer Center and received TT (sunitinib, sorafenib, pazopanib, temsirolimus, everolimus, erlotinib, or bevacizumab) over the last eight years (2003-2011) and who also had ESRD and underwent hemodialysis (HD) or peritoneal dialysis (PD). Overall survival (OS) was determined from initiation of TT to death. Results: Eleven patients (6 males; 8 with clear cell, 3 with papillary) were identified who met the above inclusion criteria. Median age was 57.4 years. Comorbidities included hypertension in 10, diabetes in 4, and hyperlipidemia in 6. Median number of TT was 4 (range, 1-6). Median time on treatment (TOT) was 769 days (range, 73-1792), Seven patients have died. Seven patients were on both HD and TT for over 1 year. Median OS was 1075 days (95% CI, 722-1428). TT related adverse events (AEs) included hypertension (HTN), hand-foot skin reaction (HFS), fatigue, diarrhea, rash and pneumonitis [Table]. There were no treatment related deaths. Conclusions: In this small retrospective series of patients with mRCC and ESRD who were treated with TT, adverse events were acceptable, and relatively prolonged disease courses were noted. [Table: see text]

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