Evaluation of Proton Pump Inhibitor (PPI) Effect for Two Formulation of Paliperidone by Utilizing a Multi-pH Dissolution Model and Physiologically Based Pharmacokinetic (PBPK) Absorption Modeling and Simulation Approach

Biopharmaceutics Applications of Physiologically Based Pharmacokinetic Absorption Modeling and Simulation in Regulatory Submissions to the U.S. Food and Drug Administration for New Drugs

The AAPS Journal ◽

10.1208/s12248-021-00564-2 ◽

2021 ◽

Vol 23 (2) ◽

Author(s):

Fang Wu ◽

Heta Shah ◽

Min Li ◽

Peng Duan ◽

Ping Zhao ◽

...

Keyword(s):

Modeling And Simulation ◽

Drug Administration ◽

Food And Drug Administration ◽

New Drugs ◽

Physiologically Based Pharmacokinetic ◽

Physiologically Based ◽

Regulatory Submissions ◽

Absorption Modeling ◽

The U.S

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Meta-Analysis of Nanoparticle Delivery to Tumors Using a Physiologically Based Pharmacokinetic Modeling and Simulation Approach

ACS Nano ◽

10.1021/acsnano.9b08142 ◽

2020 ◽

Vol 14 (3) ◽

pp. 3075-3095 ◽

Cited By ~ 16

Author(s):

Yi-Hsien Cheng ◽

Chunla He ◽

Jim E. Riviere ◽

Nancy A. Monteiro-Riviere ◽

Zhoumeng Lin

Keyword(s):

Modeling And Simulation ◽

Meta Analysis ◽

Pharmacokinetic Modeling ◽

Simulation Approach ◽

Physiologically Based Pharmacokinetic Modeling ◽

Nanoparticle Delivery ◽

Physiologically Based Pharmacokinetic ◽

Physiologically Based ◽

Pharmacokinetic Modeling And Simulation

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Utility of Physiologically Based Pharmacokinetic Absorption Modeling to Predict the Impact of Salt-to-Base Conversion on Prasugrel HCl Product Bioequivalence in the Presence of Proton Pump Inhibitors

The AAPS Journal ◽

10.1208/s12248-017-0116-2 ◽

2017 ◽

Vol 19 (5) ◽

pp. 1479-1486 ◽

Cited By ~ 7

Author(s):

Jianghong Fan ◽

Xinyuan Zhang ◽

Liang Zhao

Keyword(s):

Proton Pump Inhibitors ◽

Proton Pump ◽

Physiologically Based Pharmacokinetic ◽

Physiologically Based ◽

Absorption Modeling ◽

The Impact

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Physiologically Based Pharmacokinetic Modeling Approach to Identify the Drug–Drug Interaction Mechanism of Nifedipine and a Proton Pump Inhibitor, Omeprazole

European Journal of Drug Metabolism and Pharmacokinetics ◽

10.1007/s13318-020-00649-x ◽

2020 ◽

Author(s):

Maxime Le Merdy ◽

Ming-Liang Tan ◽

Dajun Sun ◽

Zhanglin Ni ◽

Sue-Chih Lee ◽

...

Keyword(s):

Drug Interaction ◽

Proton Pump Inhibitor ◽

Proton Pump ◽

Interaction Mechanism ◽

Pharmacokinetic Modeling ◽

Physiologically Based Pharmacokinetic Modeling ◽

Modeling Approach ◽

Physiologically Based Pharmacokinetic ◽

Physiologically Based ◽

Drug Drug Interaction

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Physiologically-based pharmacokinetic modeling and simulation of drug-drug interactions between azole antifungals, macrolide antibiotics or proton pump inhibitors and tacrolimus for provision of quantitative information to clinical practice

Proceedings for Annual Meeting of The Japanese Pharmacological Society ◽

10.1254/jpssuppl.wcp2018.0_po1-11-32 ◽

2018 ◽

Vol WCP2018 (0) ◽

pp. PO1-11-32

Author(s):

Yukio Otsuka ◽

Akira Koibuchi ◽

Atsunori Kaibara ◽

Yukako Tsukamoto ◽

Kumi Koide ◽

...

Keyword(s):

Clinical Practice ◽

Drug Interactions ◽

Modeling And Simulation ◽

Proton Pump ◽

Quantitative Information ◽

Macrolide Antibiotics ◽

Physiologically Based Pharmacokinetic Modeling ◽

Azole Antifungals ◽

Physiologically Based Pharmacokinetic ◽

Physiologically Based

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Virtual Clinical Trial Toward Polytherapy Safety Assessment: Combination of Physiologically Based Pharmacokinetic/Pharmacodynamic-Based Modeling and Simulation Approach With Drug-Drug Interactions Involving Terfenadine as an Example

Journal of Pharmaceutical Sciences ◽

10.1016/j.xphs.2016.08.002 ◽

2016 ◽

Vol 105 (11) ◽

pp. 3415-3424 ◽

Cited By ~ 13

Author(s):

Barbara Wiśniowska ◽

Sebastian Polak

Keyword(s):

Clinical Trial ◽

Drug Interactions ◽

Modeling And Simulation ◽

Safety Assessment ◽

Simulation Approach ◽

Physiologically Based Pharmacokinetic ◽

Physiologically Based

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Physiologically Based Pharmacokinetic (PBPK) Modeling and Simulation Approaches: A Systematic Review of Published Models, Applications, and Model Verification

Drug Metabolism and Disposition ◽

10.1124/dmd.115.065920 ◽

2015 ◽

Vol 43 (11) ◽

pp. 1823-1837 ◽

Cited By ~ 170

Author(s):

Jennifer E. Sager ◽

Jingjing Yu ◽

Isabelle Ragueneau-Majlessi ◽

Nina Isoherranen

Keyword(s):

Systematic Review ◽

Modeling And Simulation ◽

Model Verification ◽

Pbpk Modeling ◽

Physiologically Based Pharmacokinetic ◽

Physiologically Based

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Evaluation of Exposure Change of Nonrenally Eliminated Drugs in Patients With Chronic Kidney Disease Using Physiologically Based Pharmacokinetic Modeling and Simulation

The Journal of Clinical Pharmacology ◽

10.1177/0091270011415528 ◽

2012 ◽

Vol 52 (S1) ◽

Cited By ~ 69

Author(s):

Ping Zhao ◽

Manuela de L. T. Vieira ◽

Joseph A. Grillo ◽

Pengfei Song ◽

Ta‐Chen Wu ◽

...

Keyword(s):

Chronic Kidney Disease ◽

Kidney Disease ◽

Modeling And Simulation ◽

Pharmacokinetic Modeling ◽

Physiologically Based Pharmacokinetic Modeling ◽

Physiologically Based Pharmacokinetic ◽

Physiologically Based ◽

Pharmacokinetic Modeling And Simulation

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Impact of acute fat mobilisation on the pharmacokinetics of the highly fat distributed compound TAK-357, investigated by physiologically based pharmacokinetic (PBPK) modeling and simulation

Biopharmaceutics & Drug Disposition ◽

10.1002/bdd.2075 ◽

2017 ◽

Vol 38 (6) ◽

pp. 373-380 ◽

Cited By ~ 1

Author(s):

Akihiko Goto ◽

Yoshihiko Tagawa ◽

Yuu Moriya ◽

Sho Sato ◽

Yoshiyuki Furukawa ◽

...

Keyword(s):

Modeling And Simulation ◽

Pbpk Modeling ◽

Physiologically Based Pharmacokinetic ◽

Physiologically Based

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A Bayesian population physiologically based pharmacokinetic absorption modeling approach to support generic drug development: application to bupropion hydrochloride oral dosage forms

Journal of Pharmacokinetics and Pharmacodynamics ◽

10.1007/s10928-021-09778-5 ◽

2021 ◽

Author(s):

Nan-Hung Hsieh ◽

Frédéric Y. Bois ◽

Eleftheria Tsakalozou ◽

Zhanglin Ni ◽

Miyoung Yoon ◽

...

Keyword(s):

Drug Development ◽

Generic Drug ◽

Dosage Forms ◽

Oral Dosage ◽

Modeling Approach ◽

Physiologically Based Pharmacokinetic ◽

Physiologically Based ◽

Absorption Modeling ◽

Oral Dosage Forms ◽

Development Application

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