CLINICAL FEATURES ASSOCIATED WITH SYMPTOMATIC UNCOMPLICATED DIVERTICULAR DISEASE AND DIVERTICULITIS PATIENTS: RESULTS FROM THE ITALIAN REGISTER OF DIVERTICULAR DISEASE (REMAD)

Author(s):  
Marilia Carabotti
2012 ◽  
Vol 27 (9) ◽  
pp. 1151-1159 ◽  
Author(s):  
Bruno Annibale ◽  
Edith Lahner ◽  
Giovanni Maconi ◽  
Paolo Usai ◽  
Santino Marchi ◽  
...  

2006 ◽  
Vol 51 (3) ◽  
pp. 461-465 ◽  
Author(s):  
Antonio Tursi ◽  
Giovanni Brandimarte ◽  
Gian Marco Giorgetti ◽  
Walter Elisei

2021 ◽  
Vol 53 ◽  
pp. S120
Author(s):  
A. Gioia ◽  
G. Schirò ◽  
C. Corrado ◽  
N. Rollo ◽  
C. Severi

2010 ◽  
Vol 92 (6) ◽  
pp. 463-465 ◽  
Author(s):  
James McDaid ◽  
Claire Reichl ◽  
Ihsan Hamzah ◽  
Samantha Fitter ◽  
Laura Harbach ◽  
...  

INTRODUCTION We observed that a number of patients presenting to our clinic with diverticular fistulation were taking nicorandil for angna. Recognised side effects of nicorandil include gastrointestinal and genital ulceration. The aim of our study was to determine whether nicorandil is an aetiological agent in diverticular fistulation. PATIENTS AND METHODS We conducted a case-control study of patients with diverticular disease related enteric fistulae. Two patient groups were identified: a study group of patients with diverticular fistulae, and a control group with uncomplicated diverticular disease. The proportion of patients who had ever used nicorandil was compared between the two groups. RESULTS A total of 153 case notes were analysed, 69 patients with fistulae and 84 control patients with uncomplicated diverticular disease. Female to male ratio in both groups was 2:1. The mean age was 71 years in the fistula group and 69 years in the control diverticular disease group (P = ns). Of those with colonic fistulae, 16% were taking nicorandil compared with 2% of the control group (odds ratio 7.8; 95% confidence interval 1.5–39.1; P = 0.008). There was no significant difference in rates of ischaemic heart disease between fistula and control groups. CONCLUSIONS Nicorandil is associated with fistula formation in diverticular disease.


2018 ◽  
Vol 3 ◽  
pp. 55-55
Author(s):  
Kirien Kjossev ◽  
Roberto Cirocchi ◽  
Georgi Popivanov ◽  
Ventsislav Mutafchiyski

2019 ◽  
Vol 2019 ◽  
pp. 1-7 ◽  
Author(s):  
Antonio Tursi ◽  
Walter Elisei

Diverticulosis of the colon is the most common condition in Western societies and it is the most common anatomic alteration of the human colon. Recurrent abdominal pain is experienced by about 20% of patients with diverticulosis, but the pathophysiologic mechanisms of its occurrence are not completely understood. In the last years, several fine papers have showed clearly the role of low-grade inflammation both in the occurrence of symptoms in people having diverticulosis, both in symptom persistence following acute diverticulitis, even if the evidence available is not so strong. We do not know yet what the trigger of this low-grade inflammation occurrence is. However, some preliminary evidence found colonic dysbiosis linked to low-grade inflammation and therefore to symptom occurrence in those patients. The aim of this paper is to summarize current evidences about the role of inflammation in symptom occurrence in symptomatic uncomplicated diverticular disease and in symptom persistence after an episode of acute diverticulitis.


Sign in / Sign up

Export Citation Format

Share Document