Systematic review and meta-analysis of the prognostic significance of CpG Island Methylator Phenotype in gastric cancer

2017 ◽  
Author(s):  
Arfon Powell
Keyword(s):  
Gastric Cancer ◽  
Systematic Review ◽  
Cpg Island ◽  
Meta Analysis ◽  
Prognostic Significance ◽  
Cpg Island Methylator Phenotype ◽  
Methylator Phenotype

scholarly journals Clinical, Pathological, and Molecular Characteristics of CpG Island Methylator Phenotype in Colorectal Cancer: A Systematic Review and Meta-analysis

2018 ◽  
Vol 11 (5) ◽  
pp. 1188-1201 ◽  
Author(s):  
Shailesh M. Advani ◽  
Pragati Advani ◽  
Stacia M. DeSantis ◽  
Derek Brown ◽  
Helena M. VonVille ◽  
...  
Keyword(s):  
Colorectal Cancer ◽  
Systematic Review ◽  
Cpg Island ◽  
Meta Analysis ◽  
Molecular Characteristics ◽  
Cpg Island Methylator Phenotype ◽  
Methylator Phenotype

scholarly journals Meta-analysis of the prognostic value of CpG island methylator phenotype in gastric cancer

2018 ◽  
Vol 105 (2) ◽  
pp. e61-e68 ◽  
Author(s):  
A. G. M. T. Powell ◽  
S. Soul ◽  
A. Christian ◽  
W. G. Lewis
Keyword(s):  
Gastric Cancer ◽  
Prognostic Value ◽  
Cpg Island ◽  
Meta Analysis ◽  
Cpg Island Methylator Phenotype ◽  
Methylator Phenotype

Association between the CpG island methylator phenotype and its prognostic significance in primary pulmonary adenocarcinoma

Tumor Biology ◽  
2016 ◽  
Vol 37 (8) ◽  
pp. 10675-10684 ◽  
Author(s):  
Young Wha Koh ◽  
Sung-Min Chun ◽  
Young-Soo Park ◽  
Joon Seon Song ◽  
Geon Kook Lee ◽  
...  
Keyword(s):  
Cpg Island ◽  
Prognostic Significance ◽  
Pulmonary Adenocarcinoma ◽  
Cpg Island Methylator Phenotype ◽  
Methylator Phenotype

scholarly journals Meta-analysis of the prognostic value of CpG island methylator phenotype in rectal cancer

2018 ◽  
Vol 33 (8) ◽  
pp. 995-1000 ◽  
Author(s):  
R. F. Kokelaar ◽  
H. Jones ◽  
J. Beynon ◽  
M. E. Evans ◽  
D. A. Harris
Keyword(s):  
Rectal Cancer ◽  
Prognostic Value ◽  
Cpg Island ◽  
Meta Analysis ◽  
Cpg Island Methylator Phenotype ◽  
Methylator Phenotype

Lower LINE-1 methylation is associated with promoter hypermethylation and distinct molecular features in gastric cancer

Epigenomics ◽  
2019 ◽  
Vol 11 (15) ◽  
pp. 1651-1659
Author(s):  
Sayumi Tahara ◽  
Tomomitsu Tahara ◽  
Noriyuki Horiguchi ◽  
Masaaki Okubo ◽  
Tsuyoshi Terada ◽  
...  
Keyword(s):  
Gastric Cancer ◽  
Gastric Mucosa ◽  
Cpg Island ◽  
Methylation Status ◽  
Promoter Hypermethylation ◽  
Cpg Island Methylator Phenotype ◽  
Line1 Methylation ◽  
Methylator Phenotype ◽  
H Pylori ◽  
Mlh1 Methylation

Aim: To investigate the associations between LINE1 methylation, an indicator for genome-wide hypomethylation, molecular and clinicopathological characteristics of gastric cancer (GC) patients. Patients & methods: LINE1 methylation statuses were examined in paired cancerous, non-neoplastic mucosa from 217 GC and gastric mucosa from separate group of 224 noncancer patients. CpG island methylator phenotype, TP53 and KRAS mutation, MLH1 methylation status and promoter hypermethylation of GC related and H. pylori-related genes were examined. Results: Lower LINE1 methylation was observed in primary GC compared with non-neoplastic gastric mucosa and associated with CpG island methylator phenotype, TP53 mutation, MLH1 methylation and promoter hypermethylation of GC related and H. pylori-related genes. Conclusion: Lower LINE1 methylation correlates specific molecular subtypes and promoter hypermethylation in GC.

scholarly journals Prognostic value of CpG island methylator phenotype in gastric cancer

2018 ◽  
Vol 109 (8) ◽  
pp. 2623-2625 ◽  
Author(s):  
Huashi Xiao ◽  
Jiaxin Fu ◽  
Masanobu Abe ◽  
Jiafu Ji ◽  
Liang Zong
Keyword(s):  
Gastric Cancer ◽  
Prognostic Value ◽  
Cpg Island ◽  
Cpg Island Methylator Phenotype ◽  
Methylator Phenotype
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