CHRONIC URTICARIA IN CHILDREN: CLINICAL CHARACTERISTICS AND RESPONSE TO TREATMENT

2018 ◽  
Author(s):  
Luis Felipe Chiaverini Ensina
Keyword(s):  
Chronic Urticaria ◽  
Clinical Characteristics ◽  
Response To Treatment

The Clinical Characteristics and Prognosis of Chinese Patients With Primary Light-Chain Amyloidosis: A Retrospective Multicenter Analysis

2019 ◽  
Author(s):  
Donghua He ◽  
Fangshu Guan ◽  
Minli Hu ◽  
Gaofeng Zheng ◽  
Pan Hong ◽  
...  
Keyword(s):  
Prognostic Factors ◽  
Light Chain ◽  
Clinical Characteristics ◽  
Cardiac Involvement ◽  
Renal Involvement ◽  
Chinese Patients ◽  
Response To Treatment ◽  
Light Chain Amyloidosis ◽  
Hepatic Involvement ◽  
Serum And Urine

Abstract Objective To retrospectively identify the critical characteristics and prognostic factors of primary light-chain amyloidosis. Patients and Methods: Data were collected and compared from 91 patients who were diagnosed with primary light-chain amyloidosis at four hospitals between January 2010 and November 2018. We analyzed the clinical characteristics and performed an overall survival (OS) analysis. Results: Patients (median age, 60 years) were diagnosed with organ involvement of the kidney (91.2%), heart (56%), liver (14.3%), soft tissue (18.7%), or gastrointestinal tract (15.4%), and 68.1% of patients had more than two organs involved. Patients were most commonly treated with bortezomib-based regimens (56%), and only one patient had autologous stem cell transplantation (auto-ASCT). The median OS was 36.33 months and was affected by the ECOG score, renal involvement, cardiac involvement, hepatic involvement and negative immunofixation in the serum and urine after treatment. Multivariate analysis indicated that cardiac involvement and negative immunofixation in the serum and urine after treatment were independent prognostic factors for OS. Conclusion: Cardiac involvement and the hematologic response to treatment were independent prognostic factors for OS in primary light-chain amyloidosis patients. The type and number of organs involved is more important than the number of organs involved for the OS.

scholarly journals Newly diagnosed versus relapsed idiopathic thrombotic thrombocytopenic purpura: a comparison of presenting clinical characteristics and response to treatment

2009 ◽  
Vol 88 (10) ◽  
pp. 973-978 ◽  
Author(s):  
Alberto Alvarez-Larrán ◽  
Julio del Río-Garma ◽  
Misericòrdia Pujol ◽  
Javier de la Rubia ◽  
Manuel Hernández-Jodra ◽  
...  
Keyword(s):  
Thrombotic Thrombocytopenic Purpura ◽  
Clinical Characteristics ◽  
Response To Treatment ◽  
Newly Diagnosed ◽  
Thrombocytopenic Purpura

scholarly journals Gianotti‐Crosti syndrome‐like reaction to molluscum contagiosum–Clinical characteristics and response to treatment

2021 ◽  
Author(s):  
Christina Bürgler ◽  
Lisa Weibel ◽  
Agnes Schwieger‐Briel ◽  
Nicole Knöpfel ◽  
Isabelle Luchsinger ◽  
...  
Keyword(s):  
Clinical Characteristics ◽  
Molluscum Contagiosum ◽  
Response To Treatment

Depression in Neurological Disorders

2018 ◽  
Author(s):  
Andres M. Kanner
Keyword(s):  
Neurological Disorders ◽  
Clinical Characteristics ◽  
Psychiatric Comorbidity ◽  
Response To Treatment ◽  
Prevalence Rates ◽  
Comorbid Depression ◽  
Neurologic Disorder ◽  
Complex Relation ◽  
Neurologic Disorders ◽  
The Impact

Depression is a common psychiatric comorbidity in the major neurologic disorders (e.g, stroke, epilepsy, migraine, Alzheimer’s dementia, multiple sclerosis, and Parkinson’s disease), with average prevalence rates of 25% to 40%. The relation between depression and several of these neurologic disorders is bidirectional, that is not only are patients with these neurologic conditions at greater risk of developing depression, but patients with depression are at greater risk of developing these neurologic disorders. Furthermore, the presence of comorbid depression has been associated with a worse course of the neurologic disorder and a higher risk of failure to respond to the neurologic therapies. This chapter reviews the epidemiologic and clinical characteristics of depression in the major neurologic disorder and describes the impact it has on the course of the neurologic condition and response to treatment. Finally, it identifies those neurologic disorders in with a bidirectional relation has been identified and suggests potential pathogenic mechanisms that may be operant in their complex relation.

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