01 / A COMPARATIVE EFFICACY OF EPIDURAL TRIAMCINOLONE AND BETAMETHASONE FOR LUMBOSACRAL RADICULAR PAIN IN CANCER PATIENTS: A PROSPECTIVE RANDOMIZED STUDY.

2018 ◽  
Author(s):  
Seema Mishra
Keyword(s):  
Cancer Patients ◽  
Randomized Study ◽  
Radicular Pain ◽  
Prospective Randomized Study ◽  
Comparative Efficacy

Antiemetics in children receiving cancer chemotherapy: a double-blind prospective randomized study comparing metoclopramide with chlorpromazine.

1986 ◽  
Vol 4 (7) ◽  
pp. 1110-1113 ◽  
Author(s):  
J Graham-Pole ◽  
J Weare ◽  
S Engel ◽  
R Gardner ◽  
P Mehta ◽  
...  
Keyword(s):  
Cancer Patients ◽  
Cancer Chemotherapy ◽  
Randomized Study ◽  
Nausea And Vomiting ◽  
Prospective Randomized Study ◽  
Intensive Chemotherapy ◽  
Double Blind ◽  
Better Than

This is the first prospective randomized study comparing commonly used antiemetics in children receiving cancer chemotherapy. We compared metoclopramide (MCP) with chlorpromazine (CLP), both administered in conventional doses, in 50 cancer patients aged 6 to 18 years who were receiving emetic chemotherapy. CLP proved significantly better than MCP in reducing both the frequency of vomiting (P less than .05) and the duration of nausea and vomiting (P less than .025). Extrapyramidal reactions (EPRs) were more common in MCP-treated patients. We conclude that, in the standard doses used, CLP is a better overall antiemetic than MCP for children receiving intensive chemotherapy. However, further prospective pediatric studies of antiemetic combinations are needed.

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