Copper–oxygen Dynamics in Tyrosinase
Keyword(s):
X Ray
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To unveil the activation of dioxygen on the copper centre (Cu<sub>2</sub>O<sub>2</sub>core) of tyrosinase, we performed X-ray crystallograpy with active-form tyrosinase at near atomic resolution. This study provided a novel insight into the catalytic mechanism of the tyrosinase, including the rearrangement of copper-oxygen species as well as the intramolecular migration of copper ion induced by substrate-binding.<br>
2008 ◽
Vol 283
(32)
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pp. 22316-22324
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2012 ◽
Vol 116
(32)
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pp. 9580-9594
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2014 ◽
Vol 70
(a1)
◽
pp. C475-C475
2008 ◽
Vol 64
(a1)
◽
pp. C365-C366
2005 ◽
Vol 102
(34)
◽
pp. 12041-12046
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Keyword(s):