scholarly journals Topical Antimicrobial Microparticle-Based Polymeric Materials for Burn Wound Infection

2021 ◽  
Vol 5 (10) ◽  
pp. 1694-1702
Keyword(s):  
Wound Infection ◽  
Polymeric Materials ◽  
Burn Wound ◽  
Topical Antimicrobial

scholarly journals The Microbial Profile and Antibiotic Susceptibility in Burn Wound Infection: A Hospital Based Study

2020 ◽  
pp. 76-86
Author(s):  
P. Denen Akaa ◽  
C. N. Ahachi ◽  
E. Ojo ◽  
G. T. Jombo ◽  
S. Osuji ◽  
...  
Keyword(s):  
Wound Infection ◽  
Antibiotic Susceptibility ◽  
Continuous Process ◽  
Total Body Surface Area ◽  
Antibiotics Resistance ◽  
Burn Wound ◽  
Wound Swab ◽  
Microbial Profile ◽  
Sensitivity Pattern ◽  
Culture And Sensitivity

Aim: To determine spectrum of bacteria infecting burn wound and its antibiotic susceptibility at Benue State University Teaching Hospital (BSUTH). Study Design: A one year prospective study of the microbial profile in burn wound infection at BSUTH, Makurdi. Methodology: All patients admitted from August 2018 to July 2019 with burn wound who had wound swab microscopy culture and sensitivity (MCS) after thorough cleaning of the wound were included in the study. Data collected included the Age, Sex, Occupation, Total Body Surface Area (TBSA) of burn, injuring agent, type of burn, bacteria cultured from the wound, antibiotic susceptibility, number of days of admission and outcome of treatment. Results: Out of the 63 patients admitted, flame was the predominant injuring agent seen in 54 (85.7%) patients. The age group 21 – 30 years was the most affected, 27 constituting 42.9%. Burn wound infection occurred in 25(39.7%) patients from whom 33 bacterial isolates were recovered. Gram negative organisms Pseudomonas species and Proteus species were the commonest bacteria isolated constituting 21.21% each. Other isolates were Staphylococcus aurous 36.36%, Escherichia coli 15.15%, Klebsiella species and Staphylococcus saprophyticus (each 3.03%,). There was multiple bacteria colonization of wounds and antibiotics resistance. There was no gender difference in the burn wound infection, P =0.7819. Conclusion: The sensitivity pattern showed many of the bacteria to be resistant to commonly administered antibiotics but sensitivity patterns got are important for empirical antibiotics prescription when patients come with glaring sepsis and are waiting for wound swab microscopy culture and sensitivity. Studying the microbial profile with antibiotic resistance pattern in burn’s wound infection should be a continuous process in all burn units/departments. This will help to formulate and modify at regular intervals, a hospital/departmental antibiotic policy according to the present microbial pattern in the respective burns unit.    

Aspergillus tamarii: an uncommon burn wound infection

2018 ◽  
Vol 71 (4) ◽  
pp. 379-380 ◽  
Author(s):  
Philippe Aries ◽  
Clement Hoffmann ◽  
Jean-Vivien Schaal ◽  
Thomas Leclerc ◽  
Nicolas Donat ◽  
...  
Keyword(s):  
Wound Infection ◽  
Burn Wound ◽  
Aspergillus Tamarii

Fungal Burn Wound Infection

2016 ◽  
Vol 6 (1) ◽  
Author(s):  
Haider Abdul Lateef Mousa
Keyword(s):  
Wound Infection ◽  
Burn Wound

732 Evaluating the Cost-effectiveness, Efficacy, Safety, and Tolerance of Silver Sulfadiazine Dressings Once Daily versus Twice Daily in the Treatment of Burn Wounds

2020 ◽  
Vol 41 (Supplement_1) ◽  
pp. S197-S198
Author(s):  
Tomer Lagziel ◽  
Louis Born ◽  
Luis H Quiroga ◽  
Eliana F Duraes ◽  
Benjamin R Slavin ◽  
...  
Keyword(s):  
Length Of Stay ◽  
Wound Infection ◽  
Standard Of Care ◽  
Silver Sulfadiazine ◽  
Burn Wound ◽  
Once Daily ◽  
Preliminary Results ◽  
Pain Scores ◽  
Average Pain ◽  
Dressing Change

Abstract Introduction Topical antibacterial agents are an essential component of burn wound management. The aim is to prevent wound infection effectively and promote healing. A poorly treated wound can result in scarring or even sepsis and multi-organ dysfunction in severe cases. Topical Silver Sulfadiazine cream (SSD 1%) has been the gold standard for burn care since 1960s. Due to the immediate burst release of the drug into the exposed areas, application is relatively frequent, usually twice daily. However, it remains unknown whether twice-daily SSD dressings are superior to once-daily. Methods Our institution maintained a twice-daily dressing change standard of care until 01/01/2019. Patients admitted after that date had their dressing changed once daily. Our goal is to review outcomes for 75 patients before the change-of-practice and 75 patients after the change. Our main outcomes recorded are wound infection, average pain scores, average daily narcotic requirements and length-of-stay. Results Preliminary results of 20 pre-change-of-practice and 20 post-change-of-practice patients showed no difference in the outcomes between the two groups. The infection rates were the same for both groups (15%), average pain scores (Graph 1) for the post-change group were slightly higher (pre=5.5, post=5.8; p=0.7), average length-of-stay (Graph 2) was longer in the pre-change group (pre=9.2, post=5.7; p=0.04), and no other surgical complications were reported for patients in either group. Conclusions Preliminary results show that a once-daily dressing change of SSD, has no negative impact on burn wound outcomes. In addition, it is associated with a decreased length-of-stay. A decreased length-of-stay means reduced medical expenses for the patient and the hospital. Changing the standard-of-care to once-daily could prove beneficial. Further patient review will shed more light on the significance of these results, however so far there is no inferiority in wound healing. Applicability of Research to Practice The frequency of dressing changes directly affects staff workload who are required to spend a lot of time carefully changing dressings. In addition, patient discomfort associated with frequent dressing changes including interference with sleep hygiene and increased pain medications could also be avoided. Finally, fewer dressing changes are associated with less medical supplies and hospital utilization without putting the patient at any further risk of infection.

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