Background and Aims:Although LMA insertion is less invasive than endotracheal intubation,it also requires adequate
mouth opening and blunting of minimal airway reflexes. Propofol is considered an appropriate IV agent for LMA
insertion owing to its prompt induction and suppression of airway reflexes but induction doses required are often
associated with hypotension,pain and apnea.Sevoflurane on the other hand,has minimal respiratory irritability,better
hemodynamic stability and less apnea, but is associated with delayed jaw relaxation. Our hypothesis is that the
combination of sevoflurane and propofol may be of better outcome whereby the insertion conditions of the LMA may be
optimized adequately,at the same time the potential side-effects of individual drugs are effectively curtailed.
Methods: 90 patients aged 20-60yrs of ASA I and II, 30 in each group were induced with Propofol (2mg/kg) in Group P,
8% Sevoflurane in N O: O (67%:33%) TVB technique in Group S and Group SP with additional propofol (1mg/kg) in 2 2
Group SP after loss of eyelash reflex. Induction characteristics, hemodynamic parameters and complications were
observed.
Results: 87% of the patients of Group SP had successful LMA insertion at first attempt, compared to 53% and 40% in
Group P and Group S respectively, which was statistically significant. Less apnea was seen in Group SP(20%) as
compared to Group P(60%),which was statistically significant.
Conclusion: Our study showed that the combination group stood out to be the best with highest successful LMA
insertion at first attempt and less incidence of apnea.
Comparative Study of the Effect of Warming at Various Temperatures on Biochemical, Hematologic, and Hemodynamic Parameters During Spinal Fusion Surgery Under Intravenous Anesthesia
