A study to compare the effects of single dose intravenous dexmedetomidine and clonidine on bupivacaine spinal anaesthesia

2019 ◽  
Vol 9 (1) ◽  
pp. 52-55
Author(s):  
P Ramadevi ◽  
◽  
T Nirmaladevi ◽  
Keyword(s):  
Single Dose ◽  
Spinal Anaesthesia

scholarly journals A.245 Single-dose versus continuous spinal anaesthesia in the elderly

1996 ◽  
Vol 76 ◽  
pp. 77-78
Author(s):  
K. Chaoui ◽  
J.P. Pertek ◽  
A. Coissard ◽  
M. Artis ◽  
E. Junke ◽  
...  
Keyword(s):  
Single Dose ◽  
Spinal Anaesthesia ◽  
The Elderly ◽  
Continuous Spinal Anaesthesia

Single-dose spinal anaesthesia versus incremental dosing for lower limb vascular surgery

1999 ◽  
Vol 43 (4) ◽  
pp. 405-410 ◽  
Author(s):  
L. Lundorff ◽  
J. O. Dich-Nielsen ◽  
H. Laugesen ◽  
M. M. Jensen
Keyword(s):  
Single Dose ◽  
Vascular Surgery ◽  
Spinal Anaesthesia ◽  
Lower Limb

Effects of a single-dose preemptive pregabalin on acute and chronic pain after inguinal hernia repair with mesh under spinal anaesthesia

2016 ◽  
Vol 33 (8) ◽  
pp. 605-607 ◽  
Author(s):  
Elif Oral Ahiskalioglu ◽  
Ali Ahiskalioglu ◽  
Pelin Aydin ◽  
Zakir Arslan ◽  
Mehmet Aksoy ◽  
...  
Keyword(s):  
Chronic Pain ◽  
Single Dose ◽  
Inguinal Hernia ◽  
Hernia Repair ◽  
Inguinal Hernia Repair ◽  
Spinal Anaesthesia

scholarly journals Effect of single-dose intravenous dexamethasone on postoperative pain and postoperative nausea and vomiting in patients undergoing lower segment cesarean section under spinal anesthesia

2022 ◽  
Vol 13 (1) ◽  
pp. 31-37
Author(s):  
Nazima Memon ◽  
Juhi Bagga
Keyword(s):  
Single Dose ◽  
Spinal Anesthesia ◽  
Spinal Anaesthesia ◽  
Postoperative Nausea ◽  
Postoperative Nausea And Vomiting ◽  
Nausea And Vomiting ◽  
Lower Segment ◽  
Hemodynamic Stability ◽  
Post Operative Pain ◽  
Group D

Background: Lower segment caesarean sections (LSCS) are commonly done under spinal anaesthesia. Although spinal anaesthetic techniques are relatively safe and associated with quick and uneventful recovery, post-operative pain is a major concern after effect of spinal anaesthesia weans off. Other than pain postoperative nausea and vomiting (PONV) is one of the important side effects of spinal anaesthesia. Steroids by virtue of their anti-inflammatory effect is expected to reduce pain consequent upon inflammation and many studies have shown their efficacy in reducing pain as well as PONV in post-operative patients. Aims and Objectives: Primary objective of the study was to evaluate efficacy of single-dose dexamethasone in reducing post-operative pain. The secondary objectives were to analyse effect of single-dose dexamethasone on hemodynamic stability as well as incidence of nausea and vomiting in patients undergoing LSCS under spinal anesthesia. Materials and Methods: This was a double-blind comparative study in which 60 patients undergoing LSCS under spinal anaesthesia were included on the basis of a predefined inclusion and exclusion criteria. Written informed consent was obtained from all patients. The patients were divided into two groups: Group D: 30 patients who received IV dexamethasone 8 mg (2 ml) intravenously just before giving spinal anesthesia. Group N: 30 patients who received Normal saline (2 ml) immediately before spinal anesthesia. In both groups, hemodynamic parameters, respiratory rate, severity of post-operative pain, and incidence of PONV was compared. P value less than 0.05 was taken as statistically significant. Results: Patients in Group D had significantly less severe post-operative pain (as assessed by the Visual analog scale) and incidence of PONV (P<0.05). Significantly less post-operative rescue analgesia was required in patients who received single dose of intravenous dexamethasone (P<0.05). In terms of hemodynamic stability, both groups were found to be comparable with no statistically significant difference. Conclusion: Single-dose dexamethasone is effective in reducing post-operative pain as well as incidence of PONV in patients undergoing LSCS under spinal anesthesia.

scholarly journals HYPOTENSION AFTER SPINAL ANAESTHESIA;

2013 ◽  
Vol 20 (05) ◽  
pp. 825-831
Author(s):  
AIJAZ ALI ◽  
SHMYLA HAMID ◽  
RAJA MUSHTAQ HUSSAIN, ◽  
M. Rashid Iqbal, ◽  
Raza Ali Abidi
Keyword(s):  
Blood Pressure ◽  
Single Dose ◽  
Mean Arterial Pressure ◽  
Arterial Pressure ◽  
Spinal Anesthesia ◽  
Spinal Anaesthesia ◽  
Elective Cesarean Section ◽  
Military Hospital ◽  
Group A ◽  
Group B

Objective: Aim of the study is to compare the efficacy of Ephedrine and Phenylephrine for treatment of hypotension afterspinal anaesthesia for elective caesarean section. Study design: Randomized Clinical Trial. Setting: Operation theatre Department ofAnaesthesiology, Combined Military Hospital Quetta. Duration of study: Six month from 16th Sep 2011 to 15th March 2012. Materialand Method: Seventy women undergoing LSCS for singleton pregnancy under spinal anesthesia were randomly assigned in group A andB (35 in each group). All patients preloaded with Lactated Ringer’s solution 15ml/kg body weight 10 minutes before administration ofspinal anaesthesia. Mean Arterial Pressure (MAP) was recorded before administration of spinal anaesthesia considered as Base-lineMAP and then at 1 Minute, 3 minutes & at 5 minutes after administration of spinal anaesthesia. When hypotension developed (MAP falls>20% from base line), intravenous single dose of ephedrine administered in group A patients, while in group B, Phenylephrine was given.Blood pressure was recorded after 1 minute following drug administration and up to 3 minutes at 1 minute interval. Patient handed over forprocedure after 10 minutes of spinal block. The SPSS version 13 was applied to the data. Mean and standard deviation were computed fornumerical variables like age, weight, height, systolic blood pressure, Diastolic blood pressure, and Mean Arterial pressure; whereasfrequency and percentages were employed to assess the categorical variable like efficacy. Chi-square test was used to compare theefficacy of intravenous bolus of ephedrine and phenylephrine. Statistical significance was taken at p<0.05. Results: There wassignificant difference in the efficacy of both the drugs, in the treatment of maternal hypotension. 74.29% were successfully treated ingroup “A” with a single dose of Ephedrine, as compared to group B where 51.43% were successfully treated with a single dose ofPhenylephrine. (p-value = 0.048). Conclusions: Intravenous ephedrine has more efficacy than phenylephrine in the treatment ofmaternal hypotension after spinal anesthesia for elective cesarean section.

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