Clinical profile of acute appendicitis at tertiary care hospital

2019 ◽  
Vol 11 (1) ◽  
pp. 72-74
Author(s):  
Sanjay Anarase ◽  
◽  
Yogita Sanjay Anarase ◽  

2017 ◽  
Vol 4 (3) ◽  
pp. 929 ◽  
Author(s):  
K. Suresh Babu ◽  
S. Savitha

Background: Acute appendicitis is a common problem in children and early adult life. Appendicectomy is immediate or emergency procedure to reduce morbidity and mortality. The present study was conducted to find out clinical profile of acute appendicitis and complications of appendicectomy.Methods: This observational study was conducted among 100 patients diagnosed as acute appendicitis in tertiary care hospital during the year from 2001 to 2002. The clinical profile like age, sex, symptoms of the patients and post-operative complications were recorded. All patients underwent appendicectomy and followed post operatively.Results: Out of hundred patients, 55% were male and 45% were female. Nearly 71% of the patients belonged to the age group of 15-30 years.100% had pain abdomen, 81% had fever and 75% had vomiting. The post-operative complication was 3%.Conclusions: Acute appendicitis is very common in younger age groups shows that whenever young patients present with acute abdominal pain may be considered acute appendicitis. The complication of appendicectomy is very minimum and gives good prognosis.



Author(s):  
Vinod Kumar ◽  
Bhupen Songra ◽  
Richa Jain ◽  
Deeksha Mehta

Background: the present study was under taken to determine the role of CA-125 in the diagnosis of acute appendicitis (AA), to prevent its complications and also in preventing negative appendicectomies in tertiary care hospital. Methods: The study was conducted at a tertiary care and research center between 01/03/2018 to 30/06/2019. Patients admitted to the surgery department with diagnosis of AA were considered for the study. After informed consent, a, standardized history was obtained as a case Performa. Serum samples from all the cases with clinical diagnosis of AA were obtained and stored. Only the cases with histopathologically approved AA were included in the study. Cases operated for clinical diagnosis of AA, but not histopathologically proven AA was not included in the study. CA125 levels in cases with definitive diagnosis of AA were measured. Results: In present study, ROC curve analysis revealed the sensitivity of 87.27 % and specificity of 90.91 % when the CA 125 cut-off value of > 16.8 was taken to diagnose acute appendicitis. AUC was 0.911 with a standard error of 0.0292. Conclusion: In this study we have observed that CA125 showed a positive correlation with acute appendicitis, that was statistically not significant (P>0.05). We didn’t evaluate the correlation with the disease severity. We consider that CA125 can be used as a marker in acute appendicitis cases although further research is still needed. Keywords: CA125, Acute Appendicitis, Surgery.



2020 ◽  
Vol 13 (2) ◽  
pp. 69-72
Author(s):  
Manchala Pratap Reddy ◽  
◽  
Pogula Nagarjuna Reddy ◽  
G.Vijaya Kumar ◽  
◽  
...  


2019 ◽  
Vol 10 (1) ◽  
pp. 21-25
Author(s):  
U S Kanade ◽  
◽  
, Neeraja Nitsure ◽  


2019 ◽  
Vol 11 (1) ◽  
pp. 45-47
Author(s):  
Sanjay Anarase ◽  
◽  
Yogita Sanjay Anarase ◽  


2017 ◽  
Vol 2 (4) ◽  
pp. S40
Author(s):  
D. Sree Bhushan Raju ◽  
B. Vijay Kiran ◽  
N. Vamsi krishna ◽  
B.N.R. Ramesh ◽  
G. Anvesh ◽  
...  


2021 ◽  
Vol 8 (15) ◽  
pp. 968-971
Author(s):  
Sadiq Yunus Mulla ◽  
Sachin Sitaram Pandit ◽  
Sachin Kisan Shivnitwar

BACKGROUND Haemophilia’s are X-linked hereditary blood clotting disorders due to deficiency of factor VIII (haemophilia A) or factor IX (haemophilia B) & also has identical clinical manifestations, screening tests abnormalities and sex-linked genetic transmission. Haemophilia’s result from defects in the factor VIII / IX gene that lead to decreased amount of factor VIII / IX protein, the presence of a functionally abnormal protein, or combination of both. Haemophilia A is a classic example of an X-linked recessive trait. The severity of their bleeding depends on their factor VIII activity level; and, rarely, a woman can have very low factor VIII activity, and present with symptoms of moderate or even severe haemophilia. We wanted to study the clinical profile of patients of haemophilia admitted in a tertiary care hospital. METHODS This is a cross-sectional study enrolling 60 known cases of haemophilia A & B admitted in wards & ICU / attending OPD of a tertiary care hospital. History was obtained in detail & thorough clinical examination was carried out. Precipitating factors for bleeding (spontaneous / minor trauma / major trauma / surgical operation / dental procedure / others), family h / o bleeding were studied in detail. RESULTS Of the total 60 cases of haemophilia, majority (49) of cases were of haemophilia A and 11 cases were of haemophilia B. In the study, majority (28.33 %) of cases belonged to 12 - 20 years age group and the most common presentation was haemarthrosis (61.67 %). 6 patients had factor VIII inhibitor antibodies and all of them were of haemophilia A. CONCLUSIONS Haemarthrosis is the most common clinical presentation of haemophilia and most common cause for haemarthrosis is spontaneous bleeding. Most common joint involved in bleeding was knee joint (target joint). Presence of factor VIII inhibitor antibodies specially in haemophilia A patients is not uncommon. KEYWORDS Haemophilia, Factor VIII, Factor IX



2021 ◽  
Vol 108 (Supplement_7) ◽  
Author(s):  
Nadia Gulnaz ◽  
Sadia Tasleem ◽  
Farooq Abdullah

Abstract Traditionally acute appendicitis has been a clinical diagnosis based on patients' history and physical examination, but the accuracy of clinical diagnosis ranges from 70-95%. Pre-operative diagnosis of acute appendicitis still remains an enigmatic challenge, because no single test alone can reduce the rate of negative appendectomy. Hence some authors have recommended a combination of two or more investigations to increase accuracy and therefore the use of imaging is gaining support. The objective of the study was to determine the clinical accuracy of ultrasound, combined with inflammatory markers such as CRP, WBC, and neutrophilia keeping histopathology as the gold standard. Methods The study was conducted in a Tertiary care hospital in Peshawar from September 2014 to March 2015 on 250 patients who were clinically diagnosed with acute appendicitis. All these patients underwent u/sound scanning in addition to blood tests. Findings In this study, WBC had the highest sensitivity (77.68%) followed by neutrophil% (69.96%), CRP(67.10%), and U/Sound (62.96%) respectively. While U/Sound had the highest specificity (70.59%) followed by CRP and TLC (64.71% each) and neutrophil% (58.82%) respectively. When all the four tests were combined the sensitivity, specificity, (99.17% and 98.45%) increased significantly. When all four tests were negative, appendicitis could be safely ruled out. Conclusion Acute appendicitis is very unlikely and surgery can be safely deferred in these patients when all tests are negative thereby reducing the negative appendicectomy rates. 



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