scholarly journals Clinical-anamnestic features and quality of life in women with endometrial pathology on the background of uterine myoma.

2017 ◽  
Vol 22 (1) ◽  
pp. 81-88
Author(s):  
V. L. Dronova ◽  
S. M. Kornienko
Keyword(s):  
Quality Of Life ◽  
Uterine Myoma ◽  
Endometrial Pathology

scholarly journals Treatment of Uterine Myoma with 2.5 or 5 mg Mifepristone Daily during 3 Months with 9 Months Posttreatment Followup: Randomized Clinical Trial

2013 ◽  
Vol 2013 ◽  
pp. 1-8 ◽  
Author(s):  
Josep Lluis Carbonell ◽  
Rita Acosta ◽  
Yasmirian Pérez ◽  
Roberto Garcés ◽  
Carlos Sánchez ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Clinical Trial ◽  
Side Effects ◽  
Randomized Clinical Trial ◽  
Uterine Fibroids ◽  
Uterine Myoma ◽  
Similar Improvement ◽  
End Of Treatment ◽  
Fibroid Volume

Objectives. To evaluate the efficacy, safety, and quality of life by using 2.5 and mifepristone 5 mg daily doses to treat uterine fibroids over 3 months with a 9-month followup period. Design. Randomized clinical trial. Place. “Eusebio Hernández” Hospital, Havana, Cuba. Subjects. 220 women with symptomatic uterine fibroids. Treatment. One-half (2.5 mg) or one-whole 5 mg mifepristone tablet. Variables to Evaluate Efficacy. Changes in fibroid and uterine volumes, in symptomatic prevalence and intensity, and in quality of life. Results. After 3-month treatment, fibroid volume decreased by 27.9% (CI 95% 20–35) and 45.5% (CI 95% 37–62), in the 2.5 and 5 mg groups, respectively, P=0.003. There was no difference in the prevalence of symptoms at the end of treatment, unlike after 6- and 9-month followup when there was a difference. Amenorrhea was significantly higher in the 5 mg group, P=0.001. There were no significant differences in mifepristone side effects between the groups. Both groups displayed a similar improvement in quality of life. Conclusions. The 2.5 mg dosage resulted in a lesser reduction in fibroid size but a similar improvement in quality of life when compared to the 5 mg dose. This trial is registered with ClinicalTrials.gov NCT01786226.

scholarly journals THE EFFECT OF TREATMENT WITH MIFEPRISTONE ON THE QUALITY OF LIFE OF PATIENTS WITH UTERINE MYOMA

2017 ◽  
pp. 136-141 ◽  
Author(s):  
S. A. Levakov ◽  
N. A. Sheshukova
Keyword(s):  
Quality Of Life ◽  
Uterine Fibroids ◽  
Uterine Myoma ◽  
Large Majority ◽  
Drug Induced ◽  
Sonographic Examination ◽  
End Of Treatment ◽  
Study Results ◽  
Reduction Of Pain

Purpose of the study: evaluation of the quality of life of patients with symptomatic uterine myoma up to 12 weeks of gestation against a background of mifepristone 50 mg daily continuously for 3 months.Material and methods. The prospective study involved 141 patients with uterine myoma who received treatment with mifepristone (Gynestril®) 50 mg continuously for 3 months. In order to evaluate changes in the volume of uterine bleeding, each patient kept a diary where she registered the number of sanitary napkins used. Sonographic examination was used to evaluate the size of the uterus and fibroids. The Visual Analogue Scale (10-point VAS scale) was used to assess the pain intensity. Quality of life of patients and their satisfaction with the therapy was also evaluated by a 10-point VAS scale. The complaints, physical examination data and results of sonographic studies were recorded before and immediately after the end of treatment (1st and 2nd visits).Study results. Drug therapy with Gynestril® (mifepristone 50 mg) for patients with uterine myoma for 3 months helped to obtain a statistically significant (p < 0.001) improvement across all the evaluated parameters: in a large majority of patients, control of menstrual blood loss was achieved (decreased duration and volume of bleeding), while 85 patients (60.3%) achieved reversible drug-induced amenorrhea, and 43 patients (30.5%) - oligomenorrhea; a large majority of patients achieved reduction of pain severity according to VAS, while in 118 (83.7%) patients the parameter was estimated as “slight pain/no pain” after the end of treatment. According to the ultrasound results, a statistically significant decrease was achieved in the number of displayable fibroids (from 2.1 to 1.9 at an average), the volume of the dominant myoma node (on average by 65% from 37.34 to 13.27 cm3) and of the uterus (an average of 35% from 182.71 to 118.09 cm3). In addition, a vast majority of patients - 99.9% - evaluated the quality of life and satisfaction with treatment as high.Conclusions. Therefore, the results of the study demonstrate that Gynestril® is highly effective, safe and promising in the pharmaceutical treatment of uterine fibroids. 

Quality of life in women of late reproductive age with infertility and endometrial pathology

2017 ◽  
pp. 118-121
Author(s):  
S.M. Korniyenko ◽  
Keyword(s):  
Quality Of Life ◽  
Depressive Disorders ◽  
Well Being ◽  
Reproductive Period ◽  
Reproductive Age ◽  
Life Assessment ◽  
Infertile Women ◽  
Endometrial Pathology ◽  
Fertile Women

Research has shown that infertile women are less satisfied with their lives than fertile women, as their mental, communicative, sexual and emotional well-being is undergoing a number of changes, especially in the late reproductive period when the proportion increases anxiety and depressive disorders. The objective: сompare the quality of life parameters in infertile and fertile women of late reproductive age with endometrial pathology. Patients and methods. The study included 237 women 35–44 years with different clinical forms of endometrial pathology. A questionnaire health SF-36 is used for studying the quality of life. Results. The study of quality of life showed that patients with infertility compared with fertile women significantly higher assessed and psychological (p<0.008) and the physical component of their health (p<0.02), showed the greatest difference in emotional functioning (p<0.002). It was revealed that the longer the sterility, the worse the patients rated their physical functioning (с=-0.32, p<0.001) and mental health (с=-0.25, p<0.02), and the higher their overall health satisfaction (с=0.28, p<0.004).A subjective satisfaction with the physical and mental state is assessed. It was found that the age lowers the quality of life assessment more than a period of infertility. According to data obtained in the study of quality of life does not depend from infertility factors, but is largely determined by the presence of children. Conclusions. It is concluded that the quality of life of secondary infertile women closest to the profile of fertile women; patient late reproductive age with infertility and endometrial pathology more satisfied with their lives than fertile women with endometrial pathology similar age. Key words: endometrial pathology, late reproductive period, infertility, quality of life.

Women at extreme risk for obesity-related carcinogenesis: Baseline endometrial pathology and impact of bariatric surgery on weight, metabolic profiles and quality of life

2015 ◽  
Vol 138 (2) ◽  
pp. 238-245 ◽  
Author(s):  
Susan C. Modesitt ◽  
Peter T. Hallowell ◽  
Jill K. Slack-Davis ◽  
Ryan D. Michalek ◽  
Kristen A. Atkins ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Bariatric Surgery ◽  
Metabolic Profiles ◽  
Extreme Risk ◽  
Endometrial Pathology

Self-Compassion and Quality of Life in Adults Who Stutter

2020 ◽  
Vol 29 (4) ◽  
pp. 2097-2108
Author(s):  
Robyn L. Croft ◽  
Courtney T. Byrd
Keyword(s):  
Quality Of Life ◽  
Social Connectedness ◽  
The Self ◽  
Future Research ◽  
Self Compassion ◽  
Adults Who Stutter ◽  
And Gender ◽  
Relationship Of ◽  
The Impact

Purpose The purpose of this study was to identify levels of self-compassion in adults who do and do not stutter and to determine whether self-compassion predicts the impact of stuttering on quality of life in adults who stutter. Method Participants included 140 adults who do and do not stutter matched for age and gender. All participants completed the Self-Compassion Scale. Adults who stutter also completed the Overall Assessment of the Speaker's Experience of Stuttering. Data were analyzed for self-compassion differences between and within adults who do and do not stutter and to predict self-compassion on quality of life in adults who stutter. Results Adults who do and do not stutter exhibited no significant differences in total self-compassion, regardless of participant gender. A simple linear regression of the total self-compassion score and total Overall Assessment of the Speaker's Experience of Stuttering score showed a significant, negative linear relationship of self-compassion predicting the impact of stuttering on quality of life. Conclusions Data suggest that higher levels of self-kindness, mindfulness, and social connectedness (i.e., self-compassion) are related to reduced negative reactions to stuttering, an increased participation in daily communication situations, and an improved overall quality of life. Future research should replicate current findings and identify moderators of the self-compassion–quality of life relationship.

Misophonia: An Evidence-Based Case Report

2020 ◽  
Vol 29 (4) ◽  
pp. 685-690
Author(s):  
C. S. Vanaja ◽  
Miriam Soni Abigail
Keyword(s):  
Quality Of Life ◽  
Case Report ◽  
Case History ◽  
Pure Tone ◽  
Physiological Responses ◽  
Evidence Based ◽  
Management Option ◽  
Pure Tone Audiogram

Purpose Misophonia is a sound tolerance disorder condition in certain sounds that trigger intense emotional or physiological responses. While some persons may experience misophonia, a few patients suffer from misophonia. However, there is a dearth of literature on audiological assessment and management of persons with misophonia. The purpose of this report is to discuss the assessment of misophonia and highlight the management option that helped a patient with misophonia. Method A case study of a 26-year-old woman with the complaint of decreased tolerance to specific sounds affecting quality of life is reported. Audiological assessment differentiated misophonia from hyperacusis. Management included retraining counseling as well as desensitization and habituation therapy based on the principles described by P. J. Jastreboff and Jastreboff (2014). A misophonia questionnaire was administered at regular intervals to monitor the effectiveness of therapy. Results A detailed case history and audiological evaluations including pure-tone audiogram and Johnson Hyperacusis Index revealed the presence of misophonia. The patient benefitted from intervention, and the scores of the misophonia questionnaire indicated a decrease in the severity of the problem. Conclusions It is important to differentially diagnose misophonia and hyperacusis in persons with sound tolerance disorders. Retraining counseling as well as desensitization and habituation therapy can help patients who suffer from misophonia.

Quality of Life of Youth With Hearing Loss

ASHA Leader ◽  
2010 ◽  
Vol 15 (15) ◽  
pp. 5-6
Author(s):  
Anne Skalicky ◽  
Brenda Schick ◽  
Donald Patrick
Keyword(s):  
Quality Of Life ◽  
Hearing Loss
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