Fitting of Radial Dose Function for 192ir Brachytherapy Sources

This study used MCNPX code to investigate the brachytherapy192Ir dose distributions in water, bone, and lung tissue and performed radiophotoluminescent glass dosimeter measurements to verify the obtained MCNPX results. The results showed that the dose-rate constant, radial dose function, and anisotropy function in water were highly consistent with data in the literature. However, the lung dose near the source would be overestimated by up to 12%, if the lung tissue is assumed to be water, and, hence, if a tumor is located in the lung, the tumor dose will be overestimated, if the material density is not taken into consideration. In contrast, the lung dose far from the source would be underestimated by up to 30%. Radial dose functions were found to depend not only on the phantom size but also on the material density. The phantom size affects the radial dose function in bone more than those in the other tissues. On the other hand, the anisotropy function in lung tissue was not dependent on the radial distance. Our simulation results could represent valid clinical reference data and be used to improve the accuracy of the doses delivered during brachytherapy applied to patients with lung cancer.

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The radial dose function of low-energy brachytherapy seeds in different solid phantoms: comparison between calculations with the EGSnrc and MCNP4C Monte Carlo codes and measurements

Physics in Medicine and Biology ◽

10.1088/0031-9155/49/8/014 ◽

2004 ◽

Vol 49 (8) ◽

pp. 1569-1582 ◽

Cited By ~ 54

Author(s):

B Reniers ◽

F Verhaegen ◽

S Vynckier

Keyword(s):

Monte Carlo ◽

Low Energy ◽

Radial Dose Function ◽

Radial Dose

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An EGSnrc investigation of the air-kerma strength, dose rate constant, and radial dose function of 125I brachytherapy sources

Radiological Physics and Technology ◽

10.1007/s12194-009-0066-1 ◽

2009 ◽

Vol 2 (2) ◽

pp. 198-204 ◽

Cited By ~ 2

Author(s):

Sridhar Sahoo ◽

T. Palani Selvam

Keyword(s):

Dose Rate ◽

Rate Constant ◽

Air Kerma ◽

125I Brachytherapy ◽

Radial Dose Function ◽

Radial Dose

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Improved radial dose function estimation using current version MCNP Monte-Carlo simulation: Model 6711 and ISC3500 125I brachytherapy sources

Applied Radiation and Isotopes ◽

10.1016/j.apradiso.2004.05.070 ◽

2004 ◽

Vol 61 (6) ◽

pp. 1443-1450 ◽

Cited By ~ 19

Author(s):

Dennis M. Duggan

Keyword(s):

Monte Carlo Simulation ◽

Monte Carlo ◽

Simulation Model ◽

Function Estimation ◽

Current Version ◽

125I Brachytherapy ◽

Radial Dose Function ◽

Radial Dose ◽

Monte Carlo Simulation Model

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Determination of TG-43 dosimetric parameters for photon emitting brachytherapy sources

Journal of Biomedical Physics and Engineering ◽

10.31661/jbpe.v0i0.570 ◽

2017 ◽

Cited By ~ 1

Author(s):

A Mozaffari ◽

M Ghorbani

Keyword(s):

Monte Carlo ◽

Dose Rate ◽

Rate Constant ◽

Monte Carlo Code ◽

Treatment Planning Systems ◽

Radial Dose Function ◽

Anisotropy Function ◽

Radial Dose ◽

Good Agreement

Objective: Brachytherapy sources are widely used for the treatment of cancer. The report of Task Group No. 43 (TG-43) of American Association of Physicists in Medicine is known as the most common method for the determination of dosimetric parameters for brachytherapy sources. The aim of this study is to obtain TG-43 dosimetric parameters for 60Co, 137Cs, 192Ir and 103Pd brachytherapy sources by Monte Carlo simulation. Methods: In this study, 60Co (model Co0.A86), 137Cs (model 6520-67), 192Ir (model BEBIG) and 103Pd (model OptiSeed) brachytherapy sources were simulated using MCNPX Monte Carlo code. To simulate the sources, the exact geometric characterization of each source was defined in Monte Carlo input programs. Dosimetric parameters including air kerma strength, dose rate constant, radial dose function and anisotropy function were calculated for each source. Each input program was run with sufficient number of particle histories. The maximum type A statistical uncertainty in the simulation of the 60Co, 137Cs, 192Ir and 103Pd sources, were equal to 4%, 4%, 3.19% and 6.50%, respectively. Results: The results for dosimetry parameters of dose rate constant, radial dose function and anisotropy function for the 60Co, 137Cs, 192Ir and 103Pd sources in this study demonstrated good agreement with other studies. Conclusion: Based on the good agreement between the results of this study and other studies, the TG-43 results for Co0.A86 60Co, 67-65200 137Cs, BEBIG 192Ir and OptiSeed 103Pd sources are validated and can be used as input data in treatment planning systems (TPSs) and to validate the TPS calculations.

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