scholarly journals Juvenile Nasopharyngeal Angiofibroma

2021 ◽  
Vol 14 (1) ◽  
pp. 4
Author(s):  
Ibrahim Irsan Nasution ◽  
Ajeng Dyah Ayu WP

Juvenile nasopharyngeal angiofibroma (JNA) is a rare benign tumour affecting mostly adolescent and can be malignant because it’s aggressive, destructive, spread locally and often extends to the skull. The exact cause of JNA is unknown. JNA originates from the pterygopalatine fossa at the aperture of the pterygoid canal. Clinical symptoms include nasal obtruction, epistaxis and headaches. The diagnosis is based on anamnesia, physical and radiological examination. CT scan and MRI are the main modalities in detecting and determining tumour stage.

2016 ◽  
Vol 130 (5) ◽  
pp. 462-473 ◽  
Author(s):  
A Mishra ◽  
S C Mishra ◽  
V Verma ◽  
H P Singh ◽  
S Kumar ◽  
...  

AbstractBackground:Juvenile nasopharyngeal angiofibroma often presents with lateral extensions. In countries with limited resources, selection of a cost-effective and least morbid surgical approach for complete excision is challenging.Methods:Sixty-three patients with juvenile nasopharyngeal angiofibroma, with lateral extensions, underwent transpalatal, transpalatal-circumaxillary (transpterygopalatine) or transpalatal-circumaxillary-sublabial approaches for resection. Clinico-radiological characteristics, tumour volume and intra-operative bleeding were recorded.Results:The transpalatal approach was suitable for extensions involving medial part of pterygopalatine fossa; transpalatal-circumaxillary for extensions involving complete pterygopalatine fossa, with or without partial infratemporal fossa; and transpalatal-circumaxillary-sublabial for extensions involving complete infratemporal fossa, even cheek or temporal fossa up to zygomatic arch. Haemorrhage was greatest with the transpalatal-circumaxillary-sublabial approach, followed by transpalatal approach and transpalatal-circumaxillary approach (1212, 950 and 777 ml respectively). Tumour size (volume) was greatest with the transpalatal-circumaxillary approach, followed by transpalatal-circumaxillary-sublabial approach and transpalatal approach (40, 34 and 29 mm3). There was recurrence in three cases and residual disease in two cases. Long-term morbidity included small palatal perforation (n = 1), trismus (n = 1) and atrophic rhinitis (n = 2).Conclusion:These modified techniques, performed with endoscopic assistance under hypotensive anaesthesia, without embolisation, offer a superior option over other open procedures with regard to morbidity and recurrences.


2007 ◽  
Vol 121 (5) ◽  
pp. 460-467 ◽  
Author(s):  
I Tyagi ◽  
R Syal ◽  
A Goyal

Introduction: In the surgical management of juvenile nasopharyngeal angiofibromas the possibility of recurrences and residual tumours is always there. This study was undertaken to predict the prognostic factors determining recurrence of juvenile nasopharyngeal angiofibroma and to find out the usual sites of these tumours.Material and methods: The medical records of 95 patients with histologically proven juvenile nasopharyngeal angiofibroma were reviewed retrospectively. The commonest surgical approach used was a combined transpalatal and transmaxillary approach with a lazy S incision. A conservative lateral infratemporal approach was used in three cases.Results: Complete removal of the juvenile nasopharyngeal angiofibroma was achieved in 78 (82 per cent) of the cases in a single operation. A residual tumour was found in 17 (18 per cent) cases and recurrences occurred in 13 (13.7 per cent) cases.Conclusions: Extensions into the pterygoid fossa and basisphenoid, erosion of the clivus, intracranial extensions medial to the cavernous sinus, invasion of the sphenoid diploe through a widened pterygoid canal, feeders from the internal carotid artery, a young age and a residual tumour were risk factors found associated with recurrence of juvenile nasopharyngeal angiofibroma.


2020 ◽  
Author(s):  
Pirabu Sakthivel ◽  
Rakesh Kumar ◽  
Sreedharan Thankarajan Arunraj ◽  
Ashu Seith Bhalla ◽  
Arun Prashanth ◽  
...  

2012 ◽  
Vol 115 (11) ◽  
pp. 965-970 ◽  
Author(s):  
Suetaka Nishiike ◽  
Takashi Shikina ◽  
Hidenori Maeda ◽  
Sachiko Hio ◽  
Hidenori Inohara

2004 ◽  
Vol 131 (2) ◽  
pp. P253-P253
Author(s):  
Romain Kania ◽  
Elisabeth Sauvaget ◽  
Jean-Pierre Guichard ◽  
Jean-Pierre Chapot ◽  
Philippe Herman ◽  
...  

2021 ◽  
Vol 06 (03) ◽  
pp. 188-193
Author(s):  
Prasetyo Sarwono Putro ◽  
Meutia Apriani ◽  
Muchtar Hanafi ◽  
Vania Puspitasari

Diagnosis to treatment of Juvenile Nasopharyngeal Angiofibroma (JNA) required a multidisciplinary approach. CT scan works by combining multi-slice imaging from a device that rotates around the object. The potential of missing certain parts in the scanning process can occur. Angiography was the option to cover the CT scan pitfalls. In this case, we discussed CT scan pitfalls that can be overcome by angiography through JNA case report by showing clearer picture of the JNA and its feeding artery. 14 years old child complained of nasal congestion. On physical examination, the lesion expanded the anterior side of nasal cavity. The patient underwent a synonasal CT scan without contrast. It was obtained a heterogeneous solid mass in the nasopharynx extending to the concha and right and left maxillary sinuses. However, until the preparation of angiography, the actual size of the tumor, as well as the entire vasculature, is not yet known. The angiographic features suggested that the right side (seen in the right maxillary artery) was more dominant than the left side. However, both the right and the left finding reassured that the tumor location was more dominant in the anterior nasal cavity. The posterior lesion was also seen but did not predominate in comparison to the anterior. These findings helped clinicians in planning operative action in order to evacuate the tumor.


1979 ◽  
Vol 87 (3) ◽  
pp. 304-310 ◽  
Author(s):  
Howard L. Levine ◽  
Meredith A. Weinstein ◽  
Harvey M. Tucker ◽  
Benjamin G. Wood ◽  
Paul M. Duchesneau

Juvenile nasopharyngeal angiofibroma is a highly vascular neoplasm that lends to spread in the various fissures and foramina of the nasopharynx. Polytomography and angiography have added greatly to the diagnosis and management of this tumor through accurate preoperative assessment. Computed tomography has given an additional sophisticated, precise method for evaluating the extent of juvenile nasopharyngeal angiofibroma. Computed tomography shows, in detail, the extension of the tumor into the pterygopalatine fossa with widening of the pterygopalatine fossa and anterior bowing of the posterior wall of the maxillary sinus. With this correct information about tumor location, surgical or radiation treatment can be appropriately planned, with a probable improvement of cure rates and reduction of recurrences.


2018 ◽  
Vol 8 (29) ◽  
pp. 17-24
Author(s):  
Alexis Vuzitas ◽  
Claudiu Manea

Abstract Juvenile nasopharyngeal angiofibroma is a rare benign tumour of vascular origin found in adolescent males, originating around the sphenopalatine foramen. Although the exact pathogenesis of the tumour is not yet known, natural history and growth patterns can be predicted. JNA progressively involves the nasopharynx, nasal cavity, paranasal sinuses, pterygopalatine fossa, infratemporal fossa and, in severe cases, an orbital or intracranial extension can be seen. Early diagnosis based on clinical examination and imaging is mandatory to ensure the best resectability of the tumour, as small to moderate tumours can be managed exclusively endoscopically. Preoperative angiography can reveal the vascular sources and allow embolization to prevent significant bleeding. We present a brief literature review followed by our case series of endoscopic removal of 7 juvenile nasopharyngeal angiofibromas.


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