scholarly journals Nosocomial Native Valve Endocarditis due to Methicillin-Susceptible Staphylococcus aureus in a Patient with Psoriatic Arthritis

Author(s):  
HARUNA MIDORI KUMAMOTO ◽  
KENICHIRO YAITA
Author(s):  
Can Yilmaz Yozgat ◽  
Selcuk Uzuner ◽  
Yasin Ay ◽  
Hafize Otcu Temur ◽  
Burcu Bursal Duramaz ◽  
...  

AbstractInfective endocarditis (IE) is an uncommon infection in children. The recommended treatment for native valve endocarditis secondary to methicillin-susceptible Staphylococcus aureus infection is antistaphylococcal penicillins such as nafcillin or oxacillin. If the initial therapy fails in IE, it can lead to catastrophic results. Nowadays, daptomycin is the best alternative antimicrobial agent to treat children with severe infections, when standard antimicrobial therapy does not yield a result. Herein, we describe a case of a 16-year-old boy who had aortic valve S. aureus endocarditis with septic embolization and stroke. The patient was successfully treated only with daptomycin as well as surgical therapy in the early phase of the infection.


2013 ◽  
Vol 2013 ◽  
pp. 1-4
Author(s):  
Hadeel Zainah ◽  
Marcus Zervos ◽  
Wassim Stephane ◽  
Sara Chamas Alhelo ◽  
Ghattas Alkhoury ◽  
...  

Daptomycin has been used with success for the treatment of right-sided methicillin-resistantStaphylococcus aureus(MRSA) endocarditis. However, its efficacy has not been completely assessed for the treatment of MRSA endocarditis when it is associated with pulmonary septic emboli. Hereby, we present a case of MRSA mitral and tricuspid native valve endocarditis with pulmonary septic emboli, which was treated with daptomycin as a sole agent, resulting in worsening pulmonary infiltrates and treatment failure.


2018 ◽  
Vol 73 ◽  
pp. 91-92
Author(s):  
Alizée Maarek ◽  
Tristan Ferry ◽  
Carine Mouly-Bertin ◽  
Fadi Farhat ◽  
Julien Saison ◽  
...  

2012 ◽  
Vol 56 (8) ◽  
pp. 4511-4515 ◽  
Author(s):  
José M. Miró ◽  
José M. Entenza ◽  
Ana del Río ◽  
Maria Velasco ◽  
Ximena Castañeda ◽  
...  

ABSTRACTWe describe 3 patients with left-sided staphylococcal endocarditis (1 with methicillin-susceptibleStaphylococcus aureus[MSSA] prosthetic aortic valve endocarditis and 2 with methicillin-resistantS. aureus[MRSA] native-valve endocarditis) who were successfully treated with high-dose intravenous daptomycin (10 mg/kg/day) plus fosfomycin (2 g every 6 h) for 6 weeks. This combination was testedin vitroagainst 7 MSSA, 5 MRSA, and 2 intermediately glycopeptide-resistantS. aureusisolates and proved to be synergistic against 11 (79%) strains and bactericidal against 8 (57%) strains. This combination deserves further clinical study.


1997 ◽  
Vol 41 (8) ◽  
pp. 1815-1817 ◽  
Author(s):  
M Maurin ◽  
H Lepidi ◽  
B La Scola ◽  
M Feuerstein ◽  
M Andre ◽  
...  

We present a new experimental model of Staphylococcus aureus infective endocarditis in guinea pigs. Permanent aortic valve damage was produced by electrocoagulation after catheterization of the right carotid artery, which allowed avoidance of the intracardiac catheter to produce cardiac vegetations. Our model closely mimics pathological mechanisms of native valve endocarditis.


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