scholarly journals Lifesaving Treatment of Aortic Valve Staphylococcus aureus Endocarditis: Daptomycin and Early Surgical Therapy

2020 ◽  
Author(s):  
Can Yilmaz Yozgat ◽  
Selcuk Uzuner ◽  
Yasin Ay ◽  
Hafize Otcu Temur ◽  
Burcu Bursal Duramaz ◽  
...  
Keyword(s):  
Staphylococcus Aureus ◽  
Aortic Valve ◽  
Surgical Therapy ◽  
Initial Therapy ◽  
Native Valve ◽  
Aureus Infection ◽  
Native Valve Endocarditis ◽  
Septic Embolization ◽  
Recommended Treatment ◽  
Severe Infections

AbstractInfective endocarditis (IE) is an uncommon infection in children. The recommended treatment for native valve endocarditis secondary to methicillin-susceptible Staphylococcus aureus infection is antistaphylococcal penicillins such as nafcillin or oxacillin. If the initial therapy fails in IE, it can lead to catastrophic results. Nowadays, daptomycin is the best alternative antimicrobial agent to treat children with severe infections, when standard antimicrobial therapy does not yield a result. Herein, we describe a case of a 16-year-old boy who had aortic valve S. aureus endocarditis with septic embolization and stroke. The patient was successfully treated only with daptomycin as well as surgical therapy in the early phase of the infection.

scholarly journals Guinea pig model for Staphylococcus aureus native valve endocarditis.

1997 ◽  
Vol 41 (8) ◽  
pp. 1815-1817 ◽  
Author(s):  
M Maurin ◽  
H Lepidi ◽  
B La Scola ◽  
M Feuerstein ◽  
M Andre ◽  
...  
Keyword(s):  
Staphylococcus Aureus ◽  
Infective Endocarditis ◽  
Aortic Valve ◽  
Carotid Artery ◽  
Guinea Pig ◽  
Guinea Pigs ◽  
Native Valve ◽  
Native Valve Endocarditis ◽  
Guinea Pig Model ◽  
The Right

We present a new experimental model of Staphylococcus aureus infective endocarditis in guinea pigs. Permanent aortic valve damage was produced by electrocoagulation after catheterization of the right carotid artery, which allowed avoidance of the intracardiac catheter to produce cardiac vegetations. Our model closely mimics pathological mechanisms of native valve endocarditis.

scholarly journals Native Valve Endocarditis due toEnterococcus hiraePresenting as a Neurological Deficit

2013 ◽  
Vol 2013 ◽  
pp. 1-3 ◽  
Author(s):  
Renato Anghinah ◽  
Rafael Gustavo Sato Watanabe ◽  
Mateus Mistieri Simabukuro ◽  
Carla Guariglia ◽  
Lécio Figueira Pinto ◽  
...  
Keyword(s):  
Aortic Valve ◽  
Neurological Deficit ◽  
Enterococcus Hirae ◽  
Native Valve ◽  
Clinical Specimens ◽  
The Third ◽  
Native Valve Endocarditis ◽  
Native Aortic Valve

Enterococcus hiraeis a rare isolate in clinical specimens. We describe a case of native aortic valve endocarditis in a 56-year-old man. This is the third reported case of endocarditis due to this organism, the first without recurrence of endocarditis and the first presenting as a neurological deficit.

scholarly journals Daptomycin Failure for Treatment of Pulmonary Septic Emboli in Native Tricuspid and Mitral Valve Methicillin-ResistantStaphylococcus aureusEndocarditis

2013 ◽  
Vol 2013 ◽  
pp. 1-4
Author(s):  
Hadeel Zainah ◽  
Marcus Zervos ◽  
Wassim Stephane ◽  
Sara Chamas Alhelo ◽  
Ghattas Alkhoury ◽  
...  
Keyword(s):  
Staphylococcus Aureus ◽  
Mitral Valve ◽  
Treatment Failure ◽  
Native Valve ◽  
Methicillin Resistant ◽  
Septic Emboli ◽  
Native Valve Endocarditis ◽  
Pulmonary Infiltrates ◽  
Sole Agent

Daptomycin has been used with success for the treatment of right-sided methicillin-resistantStaphylococcus aureus(MRSA) endocarditis. However, its efficacy has not been completely assessed for the treatment of MRSA endocarditis when it is associated with pulmonary septic emboli. Hereby, we present a case of MRSA mitral and tricuspid native valve endocarditis with pulmonary septic emboli, which was treated with daptomycin as a sole agent, resulting in worsening pulmonary infiltrates and treatment failure.

Finegoldia magna: a rare cause of necrotising fasciitis

2020 ◽  
Vol 13 (5) ◽  
pp. e235115
Author(s):  
Ardit Begaj ◽  
Ross C McLean ◽  
Pudhupalayam Bhaskar
Keyword(s):  
Soft Tissues ◽  
Necrotising Fasciitis ◽  
Normal Flora ◽  
Native Valve ◽  
Skin Changes ◽  
Native Valve Endocarditis ◽  
Threatening Condition ◽  
Life Threatening ◽  
Severe Infections ◽  
Uncommon Case

Necrotising fasciitis is a life-threatening condition characterised by inflammation, affecting the soft tissues, which spreads within a fascial plane. Skin changes can be delayed and can often go unnoticed. The condition arises from a bacterial infection, commonly being of polymicrobial aetiology. We describe an uncommon case of necrotising fasciitis caused by Finegoldia magna, an anaerobic coccus, in a 40-year-old patient with diabetes. F. magna is a Gram-positive anaerobic coccus, which was previously known as Peptostreptococcus magnus. The bacteria is found in the normal flora of the urogenital tract. The bacteria is associated with severe infections such as native valve endocarditis, paravalvular abscess around a bioprosthetic valve, purulent pericarditis complicated by mediastanitis, meningitis after pneumonia and necrotising pneumonia complicated by pyopneumothorax. There have been no cases in the literature describing necrotising fasciitis of the abdominal wall caused by F. magna.

scholarly journals Giant mycotic right coronary aneurism: A rare complication of Staphylococcus aureus native valve endocarditis

2018 ◽  
Vol 73 ◽  
pp. 91-92
Author(s):  
Alizée Maarek ◽  
Tristan Ferry ◽  
Carine Mouly-Bertin ◽  
Fadi Farhat ◽  
Julien Saison ◽  
...  
Keyword(s):  
Staphylococcus Aureus ◽  
Rare Complication ◽  
Native Valve ◽  
Native Valve Endocarditis ◽  
Coronary Aneurism

scholarly journals Native Valve Endocarditis due toRalstonia pickettii: A Case Report and Literature Review

2015 ◽  
Vol 2015 ◽  
pp. 1-9
Author(s):  
Joseph Orme ◽  
Tomas Rivera-Bonilla ◽  
Akil Loli ◽  
Negin N. Blattman
Keyword(s):  
Case Report ◽  
Infective Endocarditis ◽  
Aortic Valve ◽  
Literature Review ◽  
Heart Block ◽  
Complete Heart Block ◽  
Healthy Individuals ◽  
Native Valve ◽  
Native Valve Endocarditis ◽  
First Case

Ralstonia pickettiiis a rare pathogen and even more rare in healthy individuals. Here we report a case ofR. pickettiibacteremia leading to aortic valve abscess and complete heart block. To our knowledge this is the first case report ofRalstoniaspecies causing infective endocarditis with perivalvular abscess.

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