scholarly journals Rasmussen's Encephalitis: A Rare Cause of Intractable Seizures

2022 ◽  
Vol 32 (1) ◽  
pp. 108-110
2012 ◽  
Vol 2012 ◽  
pp. 1-4 ◽  
Author(s):  
Richard A. Prayson

Rasmussen’s encephalitis is a well-established, albeit rare cause of medically intractable epilepsy. In a small number of Rasmussen's cases, a second pathology is identified, which independently can cause medically intractable seizures (dual pathology). This paper documents a case of a 13-year-old male who presented with medically intractable epilepsy. The patient underwent a series of surgical resections, early on resulting in a diagnosis of focal cortical dysplasia and later yielding a diagnosis of coexistent Rasmussen’s encephalitis, marked by chronic inflammation, microglial nodules, and focal cortical atrophy, combined with focal cortical dysplasia (Palmini et al. type IIA, ILAE type IIA). The literature on dual pathology in the setting of Rasmussen’s encephalitis is reviewed.


2002 ◽  
Vol 131 (1-2) ◽  
pp. 179-185 ◽  
Author(s):  
Renato Mantegazza ◽  
Pia Bernasconi ◽  
Fulvio Baggi ◽  
Roberto Spreafico ◽  
Francesca Ragona ◽  
...  

2018 ◽  
Vol 3 (2) ◽  
pp. 849-854
Author(s):  
Tania Licona ◽  
Alejandra Mazariegos-Rivera ◽  
Morgan Medina

Rasmussen's encephalitis (RE) is a rare but severe immune-mediated brain disorder leading to unilateral hemispheric atrophy, associated progressive neurological dysfunction with intellectual decline, and intractable seizures. It is a well-established cause of pharmacologically intractable epilepsy. The report is on a 17-month-old infant, treated at the Mario Catarino Rivas Hospital Honduras. Family history: grandfather epileptic secondary trauma from 20 years. Personal history: two previous emergency visits (at 16 months and 16 months 8 days) for convulsions for which she was admitted three days and was treated with valproic acid 30 mg/kg per day. The infant is admitted in the emergency, with a history of about three hours after onset of tonic convulsions, focused on left-side with drooling, oculogiros and relaxation of sphincters and fever of 38.5 ° C. Entered as convulsive syndrome in the study, however, as the days passed the number of seizures increased to 60 per day and was gradually presenting alterations in neurodevelopment. MRI reported leukoencephalopathy of undetermined origin and biopsy reported findings consistent with Rasmussen's syndrome. She was treated with immunoglobulin every two weeks for six doses after two months of hospitalization with achieved improvement. Currently, episodes of seizures have decreased significantly and almost not convulsing, she presented alterations in neurodevelopment.


2021 ◽  
Author(s):  
Van Trung Hoang ◽  
Thanh Tam Thi Nguyen ◽  
Nhu Quynh Vo ◽  
Vichit Chansomphou ◽  
Cong Thao Trinh

Neurology ◽  
2004 ◽  
Vol 63 (9) ◽  
pp. 1761-1762 ◽  
Author(s):  
R. T. Daniel ◽  
J.-G. Villemure ◽  
T. Granata ◽  
C. Antozzi

Author(s):  
Richard Wennberg ◽  
Sukriti Nag ◽  
Mary-Pat McAndrews ◽  
Andres M. Lozano ◽  
Richard Farb ◽  
...  

A 24-year-old woman was referred because of incompletely-controlled complex partial seizures. Her seizures had started at age 21, after a mild head injury with brief loss of consciousness incurred in a biking accident, and were characterized by a sensation of bright flashing lights in the right visual field, followed by numbness and tingling in the right foot, spreading up the leg and to the arm, ultimately involving the entire right side, including the face. Occasionally they spread further to involve right facial twitching with jerking of the right arm and leg, loss of awareness and, at the onset of her epilepsy, rare secondarily generalized convulsions. Seizure frequency averaged three to four per month. She was initially treated with phenytoin and clobazam and subsequently changed to carbamazepine 800 milligrams per day. She also complained that her right side was no longer as strong as her left and that it was also numb, especially the leg, but felt that this weakness had stabilized or improved slightly over the past two years.


2011 ◽  
Vol 33 (7) ◽  
pp. 597-600 ◽  
Author(s):  
Lucia Fusco ◽  
Nicola Specchio ◽  
Giancarlo Ciofetta ◽  
Daniela Longo ◽  
Marina Trivisano ◽  
...  

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