scholarly journals CLINICAL BREAST EXAMINATION;

2014 ◽  
Vol 21 (06) ◽  
pp. 1147-1152
Author(s):  
Afsheen Zafar

Objective: To determine sensitivity and specificity of standardized clinical breast examination (CBE) for benign and malignant breast lumps. Design: A prospective validation study. Place & duration of study: The study was conducted at Railway hospital, Rawalpindi from September 2008 to February 2010. Patients & Methods: A total of 110 female patients presenting with breast lumps were recruited in the study. All of them underwent a standardized clinical breast examination along with complete triple assessment. The sensitivity and specificity of CBE was calculated and compared with that of triple assessment in the same patient. Likelihood ratios for individual characteristics of breast lumps were also calculated. Results: Sensitivity of a structured CBE to pick up carcinoma breast in a patient with lump breast was 100% (95% CI, 0.8-1) while specificity was 94.6% (95% CI, 0.86-0.97). The likelihood ratio for carcinoma breast was 17.8 (95% CI, 7.6 - 41.7). Conclusions: The standardized CBE can differentiate between palpable benign and malignant lumps reliably. This is especially important in benign lumps where a policy of follow up clinical examination can be utilized, particularly when the investigative facilities may not be readily available.

2017 ◽  
Vol 4 (11) ◽  
pp. 3627
Author(s):  
Himabindu Bangaru ◽  
Alluru Sarath Chandra ◽  
Varun Vijay Gaiki

Background: With increased awareness about breast cancer, many women with breast lumps are attending clinics. Though benign breast lumps are most common, they may be associated with morbidity and have become cause for concern to patients. Triple assessment by clinical, radiological and pathological examination is a standard approach in the evaluation of breast lumps. Even in cases of benign breast diseases, multimodality tests are being preferred to give reassurance to patients. This study was aimed to study distribution of various benign breast lumps in relation to age at presentation, to identify sensitivity and specificity of clinical breast examination, Ultrasonography (USG) and Fine needle aspiration cytology (FNAC) methods in the evaluation of benign breast lumps and to compare with final histopathological diagnosis.Methods: A retrospective study was conducted in department of general surgery at Malla Reddy institute of medical sciences, Hyderabad from August 2013 to July 2017. 202 females with benign breast lumps were evaluated by clinical breast examination, ultrasonography (USG) and Fine needle aspiration cytology (FNAC) methods. All patients underwent excision biopsy of lump. Final histopathological report was taken as reference standard.Results: Fibroadenoma was most common in 2nd decade. Clinical breast examination and USG showed good sensitivity but less specificity than FNAC. FNAC showed both good sensitivity and specificity. There was very good degree of agreement between FNAC and histopathological diagnosis (Kappa=0.911).Conclusions: Good clinical examination can give accurate preoperative diagnosis of benign breast lumps. Triple assessment by clinical breast examination, USG and FNAC can be useful in the evaluation of benign breast lumps.


2020 ◽  
Vol 7 (6) ◽  
pp. 1733
Author(s):  
Murali S. V. ◽  
Madhusudhan B. V.

Background: In India, breast cancer is the second most common malignancy among women next to carcinoma of cervix. Since it present as a painless lump patient often neglect and present to hospital late. With increasing prominence and greater visibility in country specific health profiles around the world, breast cancer and its prevention detection and treatment will continue to emerge as a major priority and challenge for health system. As carcinoma of breast is a quite common clinical problem encountered in clinical practice, this study was an attempt to study clinical presentation modes of management of the disease.Methods: 50 patients who were admitted with a diagnosis of carcinoma breast were studied though history taking, clinical examination, relevant investigations depending on the stage of the disease. After completion, the results were analysed using Microsoft excel software and are compared with other studies.Results: Majority of patients belonging to age group 41-50 years (42%) with lump as major complaint at the time of presentation (78%). Disease in most patients was on upper outer quadrant (78%). Majority of patients belong to stage II (84%) of the disease clinically.Conclusions: The simple and effective methods of detecting the disease early like self-breast examination, clinical breast examination, ultrasonography, mammography, fine needle aspiration cytology should be made aware among the people for early detection and effective treatment of the disease.


2006 ◽  
Vol 32 ◽  
pp. S103
Author(s):  
A. Kaviani ◽  
M. Noparast ◽  
B. Delavar ◽  
M. Najafi ◽  
Z. Hatmi ◽  
...  

Author(s):  
Salene M W Jones ◽  
Tammy A Schuler ◽  
Tasleem J Padamsee ◽  
M Robyn Andersen

Abstract Background Previous studies have examined the impact of material financial hardship on cancer screening but without focusing on the psychological aspects of financial hardship. Purpose This study examined the effects of different types of financial anxiety on adherence to breast cancer screening in women at high risk of breast cancer. Adherence to cervical cancer screening was also examined to determine whether associations between financial anxiety and screening adherence were unique to breast cancer screening or more general. Methods Women (n = 324) aged 30–50 and at high risk for inherited breast cancer completed a survey on general financial anxiety, worry about affording healthcare, financial stigma due to cancer risk, and adherence to cancer screening. Multivariate analyses controlled for poverty, age, and race. Results More financial anxiety was associated with lower odds of mammogram adherence (odds ratio [OR] = 0.97, confidence interval [CI] = 0.94, 0.99), Pap smear adherence (OR = 0.98, CI = 0.96, 0.996), and clinical breast examination adherence (OR = 0.98, CI = 0.96, 0.995). More worry about affording healthcare was associated with lower odds of clinical breast examination adherence (OR = 0.95, CI = 0.91, 0.9992) but not mammogram or Pap smear adherence (p > .05). Financial stigma due to cancer risk was associated with lower odds of Pap smear adherence (OR = 0.87, CI = 0.77, 0.97) but no other cancer screenings (p > .07). Conclusions Financial anxiety may impede cancer screening, even for high-risk women aware of their risk status. Clinical interventions focused on social determinants of health may also need to address financial anxiety for women at high risk of breast cancer.


2021 ◽  
Vol 39 (15_suppl) ◽  
pp. 10028-10028
Author(s):  
Florence Lennie Wong ◽  
Janie M. Lee ◽  
Wendy M. Leisenring ◽  
Joseph Philip Neglia ◽  
Rebecca M. Howell ◽  
...  

10028 Background: Female survivors of childhood HL treated with ≥10 Gy of chest radiation are at high risk for breast cancer (BC). The Children’s Oncology Group (COG) guidelines recommend CBE annually starting at puberty and then semiannually from age 25, plus lifetime annual mammography (MAM) and breast Magnetic Resonance Imaging (MRI) starting 8y after chest radiation or age 25, whichever is later. While imaging-based screening recommendations are largely consistent with US guidelines for women at high BC risk, only the COG guidelines recommend CBE. The benefits of lifetime CBE starting from puberty for life in chest-irradiated HL survivors is unknown. Methods: Life-years (LYs) and lifetime BC mortality risk were estimated from a simulated cohort of 5-million HL survivors using the data from 5y female survivors of HL in the Childhood Cancer Survivor Study (CCSS) treated with ≥10 Gy of chest radiation. The simulated cohort underwent annual MAM+MRI from age 25 for life, with and without annual CBE from age 11 (presumed age of puberty) to age 24 and with and without semiannual CBE from age 25 for life with 100% adherence. BC included in-situ and invasive BC. Treatment-related BC incidence and non-BC mortality risks were estimated from the CCSS data. Risks at age <25 were extrapolated from the CCSS estimates while risks beyond age 50 were extrapolated additionally using the US population rates. CBE sensitivity (17.8%, in-situ and invasive BC) and specificity (98%) and MAM+MRI sensitivity (84.2-86.0%, in-situ; 96.7-97.1%, invasive) and specificity (75.3%) were obtained from the medical literature. Results: The CCSS cohort included 1057 female HL survivors. BC (all invasive) developed in three patients at age <25 (ages: 23, 24, 24). In the simulated cohort receiving no screening, lifetime BC risk was 40.8% and BC mortality was 17.5%. HL survivors around age 50 were at a 7.4-fold higher risk of developing BC and a 5.2-fold higher risk of non-BC mortality when compared with the general population. Compared to no annual CBE for ages 11-24y, undergoing annual CBE did not increase gains in LYs or reduce lifetime BC mortality relative to no screening (Table). Among those who survived to age ≥25, undergoing semiannual CBE from age 25 for life compared to no semiannual CBE also resulted in little gain in LYs or reduction in lifetime BC mortality relative to no screening. Conclusions: Lifetime CBE starting at puberty in conjunction with MAM+MRI appears to add little survival benefits compared with no CBE, suggesting that COG guidelines may be revised without adverse effect on long-term outcomes for chest-irradiated female survivors of childhood HL.[Table: see text]


2021 ◽  
Author(s):  
Kuocheng Wang ◽  
Anusha Muralidharan ◽  
Jeric Cuasay ◽  
Sandhya Pruthi ◽  
Thenkurussi Kesavadas

The Breast ◽  
2019 ◽  
Vol 43 ◽  
pp. 105-112
Author(s):  
Huan Jiang ◽  
Stephen D. Walter ◽  
Patrick Brown ◽  
Parminder Raina ◽  
Anna M. Chiarelli

Sign in / Sign up

Export Citation Format

Share Document