scholarly journals PREVALENCE OF CARDIAC DISEASES

2015 ◽  
Vol 22 (11) ◽  
pp. 1443-1448
Author(s):  
Lubna Latif ◽  
Usman Javed Iqbal

Objectives: The objective of this study was to find the prevalence of cardiacdisease among pregnant females and its impact on feto-maternal outcome. Study Design:Descriptive case series. Setting: Cardiology department Gulab Devi Chest Hospital LahoreDuration: April 2013 to April 2014. Patients & Methods: All pregnant females with cardiacdisease at any gestation with booked or un-booked statutes were included in this study. Patientswere admitted for thorough evaluation and investigations. Labor was monitored intensively. Dataregarding maternal outcomes were noted down on pre-formed questionnaire. Intra partum andpostpartum details were also noted down along with fetal outcome. The results were analyzedusing SPSS version 16.0.. Results: The total number of females presented with cardiac diseasewas 2650, out of which only 35 women were reported as pregnant. The duration of pregnancyat the time of presentation was as follows: 05 (14.2%) females presented in first trimester, 20(57.1%) in second trimester, 08 (22.8%) in third trimester and 02 (5.7%) patients presented inpostpartum period. There were 08 (22.8%) patients who had preterm labor. In terms of fetaloutcome 04 babies had birth weight of less than 1.5 kg, 12 had 1.5-2.0 kg, 15 were in rangeof 2-2.5 kg and 04 were more than 2.5 kg. 27 (77.1%) were term and 08 (22.8%) were pretermbabies. Cleft lip and atrial septal defect were the only two identified congenital anomalies.Conclusion: The overall prevalence of cardiac diseases during pregnancy was found to be1.3% in this study. Most common affected age group was of 20-25 years. Most common cardiacdisease found in our patient was mitral stenosis. 02 pregnancies ended in intrauterine fetaldeath. 08 babies were born preterm. Cleft lip and atrial septal defect were the only two identifiedcongenital anomalies in newborn delivered by our pregnant patients. Every effort should madeto create awareness regarding pre-pregnancy counseling, so that associated fetal and maternalmorbidity can be reduced.


Teratology ◽  
1975 ◽  
Vol 11 (3) ◽  
pp. 321-324 ◽  
Author(s):  
F. Clarke Fraser ◽  
Joel Rosen


2018 ◽  
Vol 15 (2) ◽  
pp. 53-57
Author(s):  
Larisa Renata Roșan ◽  
Vlad Alin Pantea ◽  
Otilia Anca Ţica ◽  
Ovidiu Ţica ◽  
Mădălina Ioana Moisi ◽  
...  

AbstractThe congenital cardiac diseases predominately affect the children, as well as the young adults, and they are the consequence of an abnormal embryological development.Atrial septal defect (DSA) is a congenital heart malformation, which can close in the first year of life, being shown by the presence of a communication between the left atrium and right atrium with the left-to-right shunt, and it subsequently produces some complications.We report the case of a 31 years-old-female without previous medical history, who was diagnosed with atrial septal defect.



EP Europace ◽  
2017 ◽  
Vol 19 (suppl_3) ◽  
pp. iii186-iii187
Author(s):  
F. Bourier ◽  
T. Reents ◽  
M. Telishevska ◽  
M. Kottmaier ◽  
V. Semmler ◽  
...  


2017 ◽  
Vol 31 ◽  
pp. S62-S63
Author(s):  
Kumar Subbaiyan ◽  
K Balamurugan ◽  
AR Raghuram ◽  
RM Krishnan ◽  
M Rajan ◽  
...  


2021 ◽  
Vol 73 ◽  
pp. S20-S21
Author(s):  
Radhapriya Yalamanchi ◽  
Refai Showkathali ◽  
Muthukumaran C. Sivaprakasam ◽  
Raja Vijendra Reddy Janke ◽  
Krishnaswamy Chandrasekharan


1998 ◽  
Vol 35 (1) ◽  
pp. 58-64
Author(s):  
Shingo Kadowaki ◽  
Michiko Sakamoto ◽  
Hiroshi Kamiishi ◽  
Takashi Tanimura

Objective It is widely known that some newborn CL/Fr mice with cleft lip and palate (CLP) also have cyanotic symptoms, which have been thought to depend on an atrial septal defect (ASD). In a previous study, we found that cyanotic mice tended to have more severe types of CLP. We hypothesize that the mechanical airway obstruction due to a poorly developed palatal shelf and unmoved tongue in CLP(+) mice might be related to the occurrence of cyanosis. The purpose of this study was to examine the relationships between ASD and cyanosis in CLP(+) newborns. Method The newborn hearts from CLP(-), noncyanotic CLP(+), cyanotic CLP(+), CL/Fr mice and ICR mice were examined histologically, and the incidence and size of ASD was determined on neonatal day (ND) 0. In CLP(-) newborns, similar procedures were performed from ND 1 to ND 4. Furthermore, in CLP(+) newborns, development of the palatal shelf was examined. Results While all the ICR mice had a well-developed atrial septum, and the incidence of ASD was 0%, about 80% of CL/Fr mice had ASD, irrespective of the presence or absence of CLP and cyanosis. On ND 0, the septum primum was significantly shorter in cyanotic CLP(+) mice than in CLP(-) mice. It also tended to be shorter in CLP(+) mice than in CLP(-) mice. Between the cyanotics and noncyanotics, there were no significant differences in the incidences of ASD and the rate of septal development. In CLP(-) mice, the septum primum developed well later and no ASD was observed on ND 4. Cyanotic newborns had significantly less developed palatal shelves than did noncyanotics. Conclusions Cyanosis may not be related to ASD and the rate of septal development, but may be related to the occurrence of CLP in this strain. Furthermore, we confirmed that some relationship exists between the development of the palatal shelf and cyanosis. The present study supports our hypothesis concerning the cause of cyanosis in CL/Fr mice.



BioMedica ◽  
2020 ◽  
Vol 36 (2S) ◽  
pp. 228-234
Author(s):  
Shamila Ijaz Munir ◽  
Amna Ahsan ◽  
Sofia Iqbal ◽  
Summera Aslam ◽  
Tayyaba Tahira ◽  
...  

<p><strong>Background and Objective:</strong> The pandemic caused by Coronavirus disease-2019 (COVID-19) is notably becoming similar to severe acute respiratory syndrome (SARS) and Middle East respiratory syndrome viruses (MERS) for causing poor feto-maternal outcome. There is not much data available about COVID-19 during pregnancy in Pakistan therefore the objective of this study is to determine maternal and fetal outcome in pregnant women affected with COVID-19 and to find out frequency of vertical transmission. <strong>Methods: </strong>This descriptive case series was conducted from 1st April 2020 to 10th May 2020 at Department of Obstetrics and Gynecology, COVID ward, Sir Ganga Ram Hospital, Lahore. A total of 20 women were included in the study that were found positive for viral RNA by Real-Time Reverse TranscriptionPolymerase Chain Reaction (rRT-PCR) of nasopharyngeal specimens. Demographics, duration of gestation, fetomaternal outcome and vertical transmission were noted in the respected proformas. The data was analyzed using Statistical Package for Social Sciences version 20. <strong>Results:</strong> The mean age of these gravid females was 29.3 &plusmn; 4.17 years. The mean gravidity was 2.60 &plusmn; 1.14 and mean gestational age was 29 &plusmn; 9.53 weeks. Among 20 patients, 4(20%) were primigravida, 5(25%) females were gravida 2 and remaining 11(55%) cases were gravida 3 and 4. The most common presenting complaints were fever followed by dry cough, myalgia and shortness of breath. Nine patients were delivered by lower segment cesarean section in which fetal distress was observed in 5(55.6%) newborns and 1(10%) newborn was preterm. Among all newborns, 02 developed respiratory distress syndrome and were admitted in pediatric intensive care unit. All pharyngeal swabs of newborns were negative at 12 and 24 hours of life. <strong>Conclusion:</strong> COVID-19 in pregnant females is not different than in general population. The fetomaternal outcome is usually good and there is no evidence of vertical transmission in any newborn.</p>



2021 ◽  
Vol 78 (19) ◽  
pp. B143
Author(s):  
Radha Yalamanchi ◽  
Refai Showkathali ◽  
Raja Reddy ◽  
C.S. Muthukumaran ◽  
K. Chandra


2021 ◽  
pp. 12-13
Author(s):  
Kumari Sneha ◽  
Gunjan Singh ◽  
Kalyan Kumar Saha ◽  
Vanita R Mhaske ◽  
Bikram Gupta

Aim & Objective: To highlight the importance of anesthetic management in a small neonate with cleft lip, cleft palate, single kidney, atrial septal defect, posted for trachea-oesophageal stula repair. Case description:Afemale baby born at 35 weeks of gestation to a 23-year-old primigravida mother by caesarean section in view of foetal distress with breech presentation .Baby had difculty in breathing and froathing from mouth. Cleft lip and cleft palate was present. Anasogastric tube was not going beyond 11 cm per oral route. Chest x ray showed coiling of tube in upper esophagus.F/S/O Type C Tracheo esophageal stula. . Plain Xray abdomen showed presence of bowel gas. Ultrasonography of the abdomen showed right renal agenesis. The left kidney was normal. Echocardiography showed presence of atrial septal defect with left to right shunt, tiny patent ductusarteriosus, mild pulmonary arterial hypertension, mild tricuspid regurgitation. Based on the presence of tracheoesophagealstula, atrialseptal defect, unilateral renal agenesis and absence of features, suggestive of alternative diagnosis infant, meet criteria of vacteral association. Discussion: VACTERL is a cluster of congenital malformations based on the non-random association of various congenital malformations in a single patient. Here “V” denotes vertebral defects or vascular anomalies (single umbilical artery), “A” anal atresia, “C” cardiac abnormalities, “TE” tracheoesophageal stula, “R"renal (kidney) abnormalities and “L” for limb anomalies) Diagnosis of VACTERL association is done only when at least three of the above mentioned congenital malformations are identied in a patient. Although 80% of these cases have vertebral defects, our case is unique as patient does not have one of the commonest occuring association i.e., vertebral anomalies. The other highlight of this case is although reports say that VACTERL babies with ipsilateral renal disorder have the same side limb defects, our case has a renal anomaly with no limb anomaly. Conclusion: Anaesthetic challenges were difcult airway, endotracheal tube placement, low respiratory reserve, small maximum allowable blood loss, long duration of surgery, risk of hypothermia, aspiratedlungs, risk of right to left shunt, difculty in securing intravenous line and intra arterialline. this case needs continuous monitoring of ECG, invasive blood.



2005 ◽  
Vol 23 (18) ◽  
pp. 4192-4197 ◽  
Author(s):  
Alistair E. Ring ◽  
Ian E. Smith ◽  
Alison Jones ◽  
Catherine Shannon ◽  
Eleni Galani ◽  
...  

Purpose The rare association between breast cancer and pregnancy means that few oncologists gain an expertise in this area. In particular, there are few published data concerning the use of chemotherapy for breast cancer during pregnancy. In this retrospective case series, we describe the experiences of five hospitals in London, United Kingdom, and how they manage this condition. Patients and Methods Retrospective searches were performed at five London hospitals in order to identify women who received chemotherapy for breast cancer while pregnant. Results Twenty-eight women were identified who had received chemotherapy for breast cancer during pregnancy. Twenty-four women received adjuvant or neoadjuvant chemotherapy for early breast cancer, and four women received palliative chemotherapy for metastatic disease. A total of 116 cycles of chemotherapy were administered during pregnancy. Sixteen women were treated with anthracycline-based chemotherapy and 12 received cyclophosphamide, methotrexate, and fluorouracil. All but one of the women were treated after the first trimester. One spontaneous abortion occurred in the woman treated during her first trimester; otherwise, there were no serious adverse consequences for the mothers or neonates. Conclusion These data provide evidence that in terms of peripartum complications and immediate fetal outcome, chemotherapy can be safely administered to women during the second and third trimesters of pregnancy.



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