scholarly journals Scoping Review: Pengaruh Terapi TURP terhadap Benign Prostatic Hyperplasia pada Lansia

2021 ◽  
Vol 3 (1) ◽  
pp. 59-64
Author(s):  
Dito Dewantoro Satriawan ◽  
Diana Wijayanti ◽  
Meta Maulida Damayanti
Keyword(s):  
Benign Prostatic Hyperplasia ◽  
Scoping Review ◽  
Transurethral Resection ◽  
Prostate Gland ◽  
The Elderly ◽  
Prostatic Hyperplasia ◽  
Flow Chart ◽  
Research Articles ◽  
Original Research ◽  
Transurethral Resection Of Prostate

Benign prostatic hyperplasia (BPH) merupakan istilah histopatologis, yaitu hiperplasia sel stroma dan sel epitel kelenjar prostat,dan bersifat jinak. Prevalensi BPH terjadi sekitar 70% pada pria di atas usia 60 tahun. Tujuan terapi pada pasien BPH adalah memperbaiki kualitas hidup pasien. Salah satu pilihan terapi untuk BPH yaitu transurethral resection of prostate (TURP) yang merupakan metode paling banyak digunakan untuk mengatasi pembesaran prostat. Tujuan penelitian ini adalah melihat gambaran pengaruh terapi TURP terhadap BPH pada lansia. Penelitian ini merupakan Scoping Review, yang diambil dari database PubMed, Springer Link, dan Science Direct dengan metode original research articles (observasional). Penelitian ini dinilai secara PICOS untuk ditentukan sebagai kriteria eligible pada prisma flow chart yang sesuai yaitu population (pasien BPH, lansia), intervention (terapi TURP), comparison (terapi lain), outcome (kesembuhan pasien BPH) terdapat 10.025 artikel, dan hasil uji berdasar atas PICOS sebanyak 10 artikel. Hasil analisis dan review dari 10 artikel ini, yaitu terapi TURP memiliki banyak fungsi serta manfaat untuk perbaikan kondisi pasien. Indikator tersebut dapat dinilai dari penurunan risiko perdarahan, waktu operasi, waktu irigasi kandung kemih, durasi kateterisasi, durasi rawat inap, perbaikan pada IPSS, QoL, Qmax, PVR, Na+ serum, K+ serum, kadar hematokrit, volume cairan irigasi, kadar hemoglobin, kreatinin serum, volume prostat dasar, IIEF-5, CTCAE, SHIM, MSHQ-EjD, dan ISI. Pasien BPH juga dapat mengalami risiko komplikasi intraoperatif ataupun pascaoperatif. Kesimpulan penelitian ini menunjukkan bahwa pengaruh terapi TURP terhadap BPH pada lansia mempunyai hasil yang cukup baik, efisien, dan efektif. Scoping Review: the Effect of TURP Therapy on Benign Prostatic Hyperplasia in the ElderlyBenign prostatic hyperplasia (BPH) is a histopathological term, which is hyperplasia of stromal cells and epithelial cells of the prostate gland, and is benign. The prevalence of BPH occurs in about 70% in men over the age of 60. The goal of therapy in BPH patients is to improve the patient's quality of life. One of the treatment options for BPH is the transurethral resection of prostate (TURP) which is the most widely used method to treat an enlarged prostate. The purpose of this study was to describe the effect of TURP therapy on BPH in the elderly. This research is a Scoping Review, which is taken from the PubMed, Springer Link, and Science Direct databases using the original research articles (observational) method. This study was assessed by PICOS to be determined as eligible criteria on the appropriate prism flow chart, namely population (BPH patients, the elderly), intervention (TURP therapy), comparison (other therapies), 10,025 articles of outcome (recovery of BPH patients), and test results. based on PICOS as many as 10 articles. The results of the analysis and review of these 10 articles are: TURP therapy has many functions and benefits for improving the patient's condition. These indicators can be assessed from the decreased risk of bleeding, time of operation, time of bladder irrigation, duration of catheterization, duration of hospitalization, improvement in IPSS, QoL, Qmax, PVR, serum Na +, serum K +, levels of hematocrit, volume of irrigation fluid, hemoglobin levels, serum creatinine, baseline prostate volume, IIEF-5, CTCAE, SHIM, MSHQ-EjD, and ISI. Patients with BPH may also be at risk of intraoperative or postoperative complications. The conclusion of this study shows that the effect of TURP therapy on BPH in the elderly has good, efficient and effective results.

scholarly journals 250 Gambaran Benigna Prostat Hiperplasia di RSUP Prof. Dr. R. D. Kandou Manado Periode Januari 2014 – Juli 2017

e-CliniC ◽  
2017 ◽  
Vol 5 (2) ◽  
Author(s):  
Filzha Adelia ◽  
Alwin Monoarfa ◽  
Angelica Wagiu
Keyword(s):  
Benign Prostatic Hyperplasia ◽  
Transurethral Resection ◽  
Prostate Gland ◽  
Descriptive Study ◽  
Prostatic Hyperplasia ◽  
Transurethral Resection Of Prostate ◽  
Age Group ◽  
Flow Disturbance ◽  
Main Complaint ◽  
Common Action

Abstract: Benign prostatic hyperplasia (BPH) is defined as stromal cell proliferation of prostate gland which causes enlargement of the gland. It manifests as urine flow disturbance, difficult to urinate, and desire to urinate, however, the urine emission is low. In 2013, Indonesia has 9.2 million cases of BPH among men aged over 60 years. This study was aimed to obtain the profile of BPH cases at Prof. Dr. R. D. Kandou Hospital Manado in the period of January 2014 to June 2017. This was a retrospective descriptive study at Medical Record Installation of Prof. Dr. R. D. Kandou Hospital. The results showed that during that period of time, the highest percentage of cases was in 2016 (38.46%) and the most common age group was 61-70 years old (46.15%). The main complaint among the patients was difficult to urinate and the most frequently performed action was transurethral resection of prostate (TURP) (51.28%). Conclusion: In this study, BPH cases were most common at the age group 61-70 years old. Moreover, TURP was the most common action performed.Keywords: benign prostatic hyperplasia Abstrak: Benigna prostat hiperplasia (BPH) didefinisikan sebagai proliferasi dari sel stromal pada prostat, yang menyebabkan pembesaran kelenjar tersebut. Manifestasi BPH dapat berupa terganggunya aliran urin, sulit buang air kecil (BAK), dan keinginan buang air kecil namun pancaran urin lemah. Pada tahun 2013 di Indonesia terdapat 9,2juta kasus BPH, umumnya diderita laki-laki berusia di atas 60 tahun. Penelitian ini bertujuan untuk mendapatkan gambaran kasus BPH di RSUP Prof. Dr. R. D. Kandou Manado periode Januari 2014 – Juli 2017. Jenis penelitian ialah deskriptif retrospektif , yang dilakukan di Instalasi Rekam Medik RSUP Prof. Dr. R. D. Kandou Manado. Hasil penelitian menunjukkan bahwa jumlah kasus BPH tertinggi pada tahun 2016 (38,46%) dan pada kelompok usia 61-70 tahun (46,15%). Keluhan utama semua pasien ialah sulit BAK. Tindakan yang paling sering digunakan yaitu transurethral resection of prostate (TURP) (51,28%). Simpulan: Kasus BPH terutama ditemukan berusia 61-70 tahun. Tindakan yang paling sering dilakukan yaitu reseksi prostat transuretra (TURP).Kata kunci: benigna prostat hiperplasia

scholarly journals Outcomes of Transurethral Resection of the Prostate in Benign Prostatic Hyperplasia Comparing Prostate Size of more than 80 Grams to Prostate Size less than 80 Grams

2015 ◽  
Vol 12 (3) ◽  
pp. 163-167 ◽  
Author(s):  
HN Joshi ◽  
IJ De Jong ◽  
RM Karmacharya ◽  
B Shrestha ◽  
R Shrestha
Keyword(s):  
Benign Prostatic Hyperplasia ◽  
Transurethral Resection ◽  
Prostate Gland ◽  
Prostatic Hyperplasia ◽  
Transurethral Resection Of Prostate ◽  
Prostate Size ◽  
The Mean ◽  
Group 2 ◽  
Large Prostate ◽  
Group 1

Background Benign prostatic hyperplasia is a condition occurring in elderly men in which the prostate gland is enlarged, hence the condition also known as benign enlargement of prostate. Benign hyperplasia can lead to both obstructive and irritative symptoms. Transurethral resection of prostate (TURP) still remains the gold standard modality of surgical treatment of obstructive lower urinary tract symptoms due to Benign hyperplasia.Objectives The objective of this study was to evaluate the outcomes of TURP in large prostate (>80 grams) in comparison to small prostate (<80 grams) in terms of efficacy, safety and complications.Methods A total of 65 cases included in this prospective study, which were operated by a single surgeon with conventional monopolar TURP using standard technique. Intra -operative and post-operative complications, pre and post- operative quality of life (QoL) and international prostate symptom score (IPSS), operative time, time to removal of catheter and hospital stay were evaluated between small and large prostate gland volumes.Results Out of 65 cases, 30 were with large prostate size i.e. 80 grams or more (group 1), and 35 cases were with small prostate size than 80 grams size (group 2). Mean age was 71.8 SD ± 6.9 years in group 1 and 68.2 SD ± 12.7 years in group 2. The mean preoperative volume of prostate was 88.8 grams (range 80-115 grams) in group 1 and 40.3 (range 20-65 grams) in group 2. The mean preoperative post void residual volume of urine (PVRU) was 244 ml SD ± 190.8 ml in group 1 and 117 ml ± 70.3 ml in group 2. Mean resection time in group 1 was 110 (range 90-130) minutes and in group 2 it was 90 minutes (range 55-115) minutes. There were quite satisfactory improvements in IPSS and QoL. No significant complications were observed except TUR syndrome in 2 cases from group 2, which were managed well in postoperative period.Conclusion With meticulous resection and intra-operative haemostasis using continuous out flow resectoscope, conventional monopolar TURP is equally safe and effective in large size prostate as compare in small size.Kathmandu University Medical Journal Vol.12(3) 2014; 163-167

scholarly journals Pathogenetic therapy of benign prostatic hyperplasia and prostatic intraepithelial neoplasia

2020 ◽  
Vol 13 (4) ◽  
pp. 66-74
Author(s):  
S.S. Krasnyak ◽  
◽  
Keyword(s):  
Benign Prostatic Hyperplasia ◽  
Prostate Gland ◽  
Intraepithelial Neoplasia ◽  
The Elderly ◽  
Prostatic Intraepithelial Neoplasia ◽  
Prostatic Hyperplasia ◽  
Common Disease ◽  
Phosphodiesterase 5 Inhibitors ◽  
Surgical Methods ◽  
Phosphodiesterase 5

Introduction. Benign prostatic hyperplasia (BPH) is a neoplasm and clinically occurred by progressive enlargement of the prostate. However, prostate neoplasm can also be malignant, which is come out from high-grade prostatic intraepithelial neoplasia (PIN). It is a proven precancerous condition. Purpose. Тo evaluate the data published on September and October 2020 on the prevalence, pathogenesis of BPH and PIN and methods of their treatment. Materials and methods. The search results in scientific databases PubMed, MEDLINE, Embase were analyzed for the queries «BPH», «PIN», «epidemiology of BPH», «pathogenesis», «treatment of PIN». Results. BPH is a very common disease in the elderly population. The pathogenesis of BPH includes age, genetics or hormones disorders, growth factors, inflammation, and lifestyle factors. PIN is the only common precursor of prostatic cancer. The main treatment methods are 5α-reductase inhibitors, phosphodiesterase-5 inhibitors, and surgical methods. In addition, plant active molecules are also widely used in the treatment of BPH and PIN. Conclusions. While 5α-reductase and phosphodiesterase-5 inhibitors treatment, as well as surgical methods have a lot of adverse events and complications, a unique herbal complex Gardaprost was developed, which suppresses hyperplasia of prostate. Curcumin, genistein and epigalocatechin-3- gallate, which are part of the preparation, form a safe agent aimed at combating the growth of the prostate gland in BPH, and also has a significant effect in the prevention of exacerbations of chronic prostatitis and malignancy in patients with PIN.

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