scholarly journals Comparison of Efficacy and Safety of Hydroxychloroquine and Teneligliptin in Type 2 Diabetes Patients who are Inadequately Controlled with Glimepiride, Metformin and Insulin therapy: A Randomized Controlled Trial with Parallel Group Design

2017 ◽  
Vol 2 (1) ◽  
pp. 033-040 ◽  
Author(s):  
Ahsan Sajjad
2015 ◽  
Vol 2015 ◽  
pp. 1-7
Author(s):  
Shi-Hui Cheng ◽  
Amin Ismail ◽  
Joseph Anthony ◽  
Ooi Chuan Ng ◽  
Azizah Abdul Hamid ◽  
...  

Objectives. Optimizing glycemic control is crucial to prevent type 2 diabetes related complications.Cosmos caudatusis reported to have promising effect in improving plasma blood glucose in an animal model. However, its impact on human remains ambiguous. This study was carried out to evaluate the effectiveness ofC. caudatuson glycemic status in patients with type 2 diabetes.Materials and Methods. In this randomized controlled trial with two-arm parallel-group design, a total of 101 subjects with type 2 diabetes were randomly allocated to diabetic-ulam or diabetic controls for eight weeks. Subjects in diabetic-ulam group consumed 15 g ofC. caudatusdaily for eight weeks while diabetic controls abstained from takingC. caudatus.Both groups received the standard lifestyle advice.Results. After 8 weeks of supplementation,C. caudatussignificantly reduced serum insulin (−1.16 versus +3.91), reduced HOMA-IR (−1.09 versus +1.34), and increased QUICKI (+0.05 versus −0.03) in diabetic-ulam group compared with the diabetic controls. HbA1C level was improved although it is not statistically significant (−0.76% versus −0.37%).C. caudatuswas safe to consume.Conclusions.C. caudatussupplementation significantly improves insulin resistance and insulin sensitivity in patients with type 2 diabetes.


2020 ◽  
Vol Volume 13 ◽  
pp. 423-431 ◽  
Author(s):  
Nuntakorn Thongtang ◽  
Jirasak Piyapromdee ◽  
Natthakan Tangkittikasem ◽  
Kittichai Samaithongcharoen ◽  
Nithiwat Srikanchanawat ◽  
...  

Diabetes Care ◽  
2014 ◽  
Vol 37 (8) ◽  
pp. 2168-2176 ◽  
Author(s):  
Guillermo Umpierrez ◽  
Santiago Tofé Povedano ◽  
Federico Pérez Manghi ◽  
Linda Shurzinske ◽  
Valeria Pechtner

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