Introduction: Colorectal cancer is one of the most common cancers in Ontario and poses a high burden among many Indigenous populations. There are two aims for this short communication: (1) highlight colorectal risk factor findings from a population-based case-control study, (2) highlight trends and challenges of colorectal cancer research among Indigenous populations in Ontario.Methods: Prevalence of cigarette smoking, obesity, diet and family history of colorectal cancer were estimated using the Indigenous identifier in the Ontario Familial Colon Cancer Registry (OFCCR) from 1999-2007 and then compared using age-adjusted odds ratio (with 95% confidence intervals) between cases and controls.Results: There were 66 Indigenous cases and 23 Indigenous controls. Cigarette smoking and obesity were higher in cases, but not statistically significant.Discussion and Conclusions: Findings were consistent with previous literature among Indigenous populations. Colorectal cancer risk factor and screening uptake information is limited among Indigenous populations; however, self-reported screening data suggest low colorectal screening uptake. Small sample size and poor Indigenous identification questions make it challenging to comprehensively understand cancer risk factors and burden in these populations.
The Description of Polymorphism of CYP1A1*2A rs4646903 (TgC) Gene as Colorectal Cancer Risk Factor In Medical Study Programs and Doctor Profession 2012-2014 UIN Syarif Hidayatullah Jakarta