scholarly journals Evaluation of Some Biochemical parameters in Clinically Normal lactating and Ovine Mastitis

2014 ◽  
Vol 38 (2) ◽  
pp. 74-78
Author(s):  
AL-Hadithy H. AH.
Keyword(s):  
Biochemical Parameters ◽  
Serum Iron ◽  
Binding Capacity ◽  
Transferrin Saturation ◽  
Serum Copper ◽  
Reference Ranges ◽  
Iron Binding ◽  
Biochemical Tests ◽  
Clinically Normal ◽  
Iron Binding Capacity

     The aim of the present work was to determine the serum iron, total iron binding capacity (TIBC), unbound iron binding capacity (UIBC), transferrin saturation percentage (TS%) and Serum Copper in normal lactating and Ovine mastitis. The study was conducted on 50 clinically normal lactating and 50 ewes affected with staphylococcal mastitis (19 clinical and 31 subclinical), both groups aged 2-5 years in Salah Al-Din governorate. The blood samples were collected from jugular vein during the period October 2012 untill April 2013. The separated sera were directly used for measurement of investigated biochemical tests. The results showed that the ranges and means ± SE of normal lactating and Ovine mastitis were as follows; serum iron 29.81-39. 63µmol /L and 33.38 ± 0.4 µmol /L, 8.76 - 34.11 µmol /L and 20.42 ± 0.98 µmol /L respectively, TIBC 44.7-79.89 µmol /L and  62.03 ±1.65µmol /L, 43.24 - 125.72 µmol /L and 91.24 ± 2.49 µmol /L respectively, UIBC 14.71 - 40.27 µmol /L and 28.57 ± 1.31 µmol /L, 13.41- 113.25 µmol /L and 66.54 ± 3.23µmol /L respectively, TS% 47.92 -71.79 and 55.08 ± 1.01, 14.1 - 65.76 and 26.73 ± 2.71 respectively, and serum copper 13.97 - 23.61 µmol /L and 17.99 ± 0.39µmol /L, 7.1 - 16.09 µmol/L and 11.8 ± 0.32 µmol /L respectively. However, a significant (P<0.05) differences between clinically normal and ewes affected with mastitis were recorded in all the measured parameters.The present data records reference ranges and means ± SE of some biochemical parameters in normal lactating and Ovine mastitis with a significant differences between them.

scholarly journals Determination of some biochemical parameters in clinically healthy and anemic dromedary camels

2017 ◽  
Vol 40 (2) ◽  
pp. 42-47
Author(s):  
Al-Hadithy H. AH.
Keyword(s):  
Biochemical Parameters ◽  
Serum Iron ◽  
Binding Capacity ◽  
Iron Concentration ◽  
Transferrin Saturation ◽  
Reference Ranges ◽  
Iron Binding ◽  
Jugular Veins ◽  
Iron Deficient ◽  
Iron Binding Capacity

     The study was conducted on 150 healthy and 102 diagnosed iron deficient anemic camels to determine serum iron, total iron binding capacity, unbound iron binding capacity, transferrin saturation, copper and cobalt concentrations. The normal (81 males and 69 females) and anemic (48 males and 54 females) groups both aged between 1-15 years in Najaf governorate- Iraq. Blood samples were collected from the jugular veins into plain tubes during the period November 2014 until May 2015, and the separated sera were used for the measurement of studied parameters. Results showed that the ranges and means ± SE in normal and anemic camels were as follows; Serum iron concentration was 7.37-19.48 μmol/L and 12±0.22 μmol/L, 1.52-15.70 μmol/L and 8.43±0.21 μmol/L, respectively, TIBC 73.80-108.47 μmol/L and 89.19±0.7 μmol/L, 93.12-135.32 μmol/L and 111.28±1.02 μmol/L, respectively, UIBC 57.5-95.25 μmol/L and 76.5±0.74 μmol/L, 83.27-125.69 μmol/L and 102±1.06 μmol/L, respectively, TS% 7.80- 24.04 %  and 14.3 ±0.27%, 1.22-14.79% and 7.6±0.21%, respectively, serum copper 6.28-16.5 μmol/L and 11±0.2 μmol/L, 3.67-12.40 μmol/L and 7±0.19 μmol/L, respectively and serum cobalt 0.84-6.78 μmol/L and 3±0.13 μmol/L, 0.42-6.42 μmol/L and 2.67±0.16 μmol/L, respectively. However, There was a significant (P<0.05) decrease in serum iron, TS% and copper. While, there was a significant (P<0.05) increase in serum TIBC and UIBC of anemic camels in comparison with normal control. The cobalt concentrations were almost similar in both groups. The present data recorded reference ranges and mean values of specific biochemical parameters in clinically normal and anemic camels with significant differences between them.

Serum iron and total iron-binding capacity compared with serum ferritin in assessment of iron deficiency.

1981 ◽  
Vol 27 (2) ◽  
pp. 276-279 ◽  
Author(s):  
F Peter ◽  
S Wang
Keyword(s):  
Iron Deficiency ◽  
Serum Ferritin ◽  
Serum Iron ◽  
Binding Capacity ◽  
Transferrin Saturation ◽  
Total Iron ◽  
Iron Binding ◽  
Total Iron Binding Capacity ◽  
Iron Deficient ◽  
Iron Binding Capacity

Abstract Ferritin values for 250 selected sera were compared with values for iron, total iron-binding capacity (TIBC), and transferrin saturation, to assess the potential of the ferritin assay for the detection of latent iron deficiency. The specimens were grouped (50 in each group) according to their values for iron and TIBC. In Group 1 (low iron, high TIBC) the saturation and ferritin values both indicated iron deficiency in all but one. In the 100 specimens of Groups 2 (normal iron, high TIBC) and 4 (normal iron, high normal TIBC), the saturation values revealed 16 iron-deficient cases, the ferritin test 55. For Groups 3 (low iron, normal TIBC) and 5 (low iron, low TIBC), the ferritin test revealed fewer cases of iron deficiency than did the saturation values (37 cases vs 51 cases, in the 100 specimens). Evidently the ferritin test detects iron deficiency in many cases for whom the serum iron and TIBC tests are not positively indicative. The correlation of serum ferritin with iron, TIBC, and transferrin saturation in the five groups was good only in the case of specimens for which the TIBC was normal; if it was abnormal the correlation was very poor.

scholarly journals Gambaran status besi pada pasien penyakit ginjal kronik stadium 5 dengan anemia yang menjalani hemodialisis reguler

e-CliniC ◽  
2016 ◽  
Vol 4 (2) ◽  
Author(s):  
Bryan J. Silaban ◽  
Cerelia Sugeng ◽  
Bradley J. Waleleng
Keyword(s):  
End Stage Renal Disease ◽  
Serum Iron ◽  
Binding Capacity ◽  
Transferrin Saturation ◽  
Total Iron ◽  
Iron Binding ◽  
Total Iron Binding Capacity ◽  
Stage Renal Disease ◽  
End Stage ◽  
Iron Binding Capacity

Abstract: Chronic kidney disease (CKD) is a pathological condition with a variety of etiology, resulting in progressively decreased renal function which is often ended with kidney failure. Chronic kidney disease has a global prevalence of 800 per million of population and the incidence of end-stage renal disease ranges from 150 to 200 per million of population. Complications often occur at the end-stage renal disease inter alia anemia with a rate of 80-90%. This study was aimed to obtain the profile of stage-5 CKD patients with anemia and regular hemodialysis was performed on them. This was a descriptive-retrospective study using data of medical records at Prof. Dr. R. D. Kandou General Hospital from January 2015 to October 2016. There were six observed variables as follows: age, gender, serum iron (SI), total iron binding capacity (TIBC), transferrin saturation, and ferritin. The results showed that of the 48 CKD patients with anemia, there were 24 males and 24 females. The majority were aged 60-69 years (33%) and had normal SI level in 30 patients (67%); decreased TIBC in 35 patients (75%); normal transferrin saturation in 26 patients (54%); and increased ferritin level in 38 patients (81%). Conclusion: Majority of the patients were 60-69 years old and had normal level of SI, decreased TIBC, normal transferrin saturation, and increased levels of ferritin. There was no difference in case number of both sexes.Keywords: serum iron, total iron binding capacity, transferrin saturation, ferritin Abstrak: Penyakit Ginjal Kronik (PGK) adalah suatu keadaan patologis dengan etiologi yang beragam, terjadi penurunan fungsi ginjal secara progresif, dan biasanya berakhir dengan gagal ginjal. Penyakit ginjal kronik merupakan salah satu masalah kesehatan di dunia dengan prevalensi 800 per juta populasi dan insidensi end-stage renal disease (ESRD) 150-200 per juta populasi di dunia. Komplikasi sering terjadi pada PGK stadium akhir antara lain anemia dengan persentase mencapai 80-90%. Penelitian ini bertujuan untuk mendapatkan profil pasien PGK stadium 5 dengan anemia dan menjalani hemodialisis reglular. Jenis penelitian ialah deskriptif-retrospektif menggunakan data sekunder dari catatan rekam medik periode Januari 2015 – Oktober 2016 di RSUP Prof. Dr. R. D. Kandou Manado dengan enam variabel penelitian, yaitu usia, jenis kelamin, serum iron (SI), total iron binding capacity (TIBC), saturasi transferin, dan feritin. Dari 48 data rekam medik pasien yang memenuhi kriteria inklusi ditemukan bahwa mayoritas pasien berumur 60-69 tahun (33%), laki-laki maupun perempuan berjumlah sama, mayoritas pasien memiliki kadar SI normal berjumlah 30 pasien (67%), kadar TIBC menurun berjumlah 35 pasien (75%), saturasi transferin normal berjumlah 26 pasien (54%), dan kadar feritin meningkat berjumlah 38 pasien (81%). Simpulan: Mayoritas pasien PGK stadium 5 yang menjalani hemodialisis reguler berusia 60-69 tahun, laki-laki dan perempuan berjumlah sama, serta memiliki kadar SI normal, penurunan TIBC, saturasi transferin normal, dan peningkatan kadar feritin. Kata kunci: serum iron, total iron binding capacity, saturasi transferin, feritin

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