Endovascular treatment of cerebral venous thrombosis.

2021 ◽  
Vol 26 (5) ◽  
pp. 24-29
Author(s):  
A. A. Kulesh ◽  
A. O. Karakulov
Keyword(s):  
Blood Flow ◽  
Venous Thrombosis ◽  
Endovascular Treatment ◽  
Cerebral Venous Thrombosis ◽  
Clinical Case ◽  
Lymphoblastic Leukemia ◽  
Prolonged Administration ◽  
Local Thrombolysis ◽  
Cerebral Sinus ◽  
Transverse Sinuses

The article describes a clinical case of cerebral venous thrombosis involving the deep venous system in a 42-year-old patient suffering from acute lymphoblastic leukemia. As the patient’s condition progressively deteriorated despite anticoagulant therapy, endovascular treatment was attempted. Transvenous thrombectomy and local thrombolysis were performed, which made it possible to achieve only partial recanalization. Further prolonged administration of alteplase into the cerebral sinus through a microcatheter facilitated complete recanalization of the direct and transverse sinuses. The restoration of blood flow was accompanied by regression of neurological deficit. This case is discussed in the context of modern approaches to endovascular treatment of cerebral venous thrombosis.

Abstract WP2: Trends of Endovascular Treatment in Cerebral Venous Thrombosis: Estimations From Nationwide Inpatient Sample

Stroke ◽  
2018 ◽  
Vol 49 (Suppl_1) ◽  
Author(s):  
Fazeel M Siddiqui ◽  
Matthew Weber ◽  
Sudeepta Dandapat ◽  
Nazan Aksan ◽  
Steve Scaife ◽  
...  
Keyword(s):  
Venous Thrombosis ◽  
Endovascular Treatment ◽  
Cerebral Venous Thrombosis ◽  
Nationwide Inpatient Sample

scholarly journals Epidemiology, Endovascular Treatment, and Prognosis of Cerebral Venous Thrombosis: US Center Study of 152 Patients

2017 ◽  
Vol 6 (6) ◽  
Author(s):  
Kristin Salottolo ◽  
Jeffrey Wagner ◽  
Donald F. Frei ◽  
David Loy ◽  
Richard J. Bellon ◽  
...  
Keyword(s):  
Venous Thrombosis ◽  
Endovascular Treatment ◽  
Cerebral Venous Thrombosis ◽  
Center Study

Thalamic Hemorrhagic Stroke in the Term Newborn: A Specific Neonatal Syndrome With Non-uniform Outcome

2017 ◽  
Vol 32 (8) ◽  
pp. 746-753 ◽  
Author(s):  
Laura Merlini ◽  
Sylviane Hanquinet ◽  
Joel Fluss
Keyword(s):  
Venous Thrombosis ◽  
Cerebral Venous Thrombosis ◽  
Hemorrhagic Stroke ◽  
Late Onset ◽  
Predicting Factors ◽  
Anterior Thalamus ◽  
Cerebral Sinus Venous Thrombosis ◽  
Cerebral Sinus ◽  
Deep Cerebral Venous Thrombosis

Background: Neonatal thalamic hemorrhagic stroke is related to cerebral sinus venous thrombosis and associated with neurological sequelae. Predicting factors are however lacking. Methods: Clinical and radiological findings at onset and on follow-up of 5 neonates with thalamic hemorrhage stroke are described. Results: All neonates presented with abrupt lethargy, ophistotonos, irritability and/or seizures. The thalamic hemorrhagic stroke was most often unilateral (4/5), involving the posterior/entire thalamus in 3 cases and the anterior thalamus in 2. Cerebral venous thrombosis was identified in a single patient. At follow-up, children with unilateral anterior thalamic hemorrhagic stroke demonstrated thalamic atrophy without neurological symptoms, whereas children whose thalamus lesion was extensive exhibit a porencephalic cavity and presented with late-onset epilepsy. Discussion: Although deep cerebral venous thrombosis is probably the cause of neonatal thalamic hemorrhagic stroke, its radiological evidence is challenging. Outcome seems dependent of the size and location of thalamic hemorrhagic stroke. Epilepsy is a frequent morbidity after thalamic hemorrhagic stroke.

scholarly journals Treatment of Progressive Cerebral Sinuses Thrombosis with Local Thrombolysis

2012 ◽  
Vol 18 (1) ◽  
pp. 89-96 ◽  
Author(s):  
R. Mohammadian ◽  
B. Sohrabi ◽  
R. Mansourizadeh ◽  
F. Mohammadian ◽  
A. Nazempour ◽  
...  
Keyword(s):  
Venous Thrombosis ◽  
Cerebral Venous Thrombosis ◽  
Clinical Symptoms ◽  
Oral Contraceptive Pill ◽  
Anticoagulation Therapy ◽  
Recombinant Tissue Plasminogen Activator ◽  
Visual Field Defects ◽  
Blurred Vision ◽  
Local Thrombolysis

Cerebral venous thrombosis (CVT) is a potentially serious disease, with nonspecific clinical symptoms and an unpredictable outcome. Despite adequate anticoagulation, a patient's clinical condition can rapidly deteriorate. The aim of this study was to evaluate the efficacy of local thrombolysis in these patients. Consecutive patients with progressive cerebral venous thrombosis between October 2008 and January 2011 were enrolled prospectively. Progressive CVT was defined as the persistence of neurologic findings (headache, blurred vision, and visual field defects) despite at least four days (or 48 hours in patients with involvement of more than one sinus) on full anticoagulation therapy with heparin and development of focal neurologic deficits or cortical hemorrhage. We excluded patients with large hematomas and predisposing malignancies like leukemia. All patients underwent local thrombolysis with 30 mg recombinant tissue plasminogen activator (rtPA). Overall, 26 patients were enrolled with a mean age of 35.5 years (range 18 to 56 years). Six patients (23%) were male and twenty patients (77%) were female. The most common presenting feature was headache and the most common neurologic finding was papilledema, which was present in all patients. Eighty-five percent of women had a history of oral contraceptive pill consumption. Successful recanalization was achieved in all patients except one (96.2%). Neurological examinations and follow-up assessments were based on a modified Rankin scale (mRS). Favorable outcome and recovery was defined as a mRS score of 0–1. Follow-up assessments at the third week showed that 25 out of 26 recovered, with 18 having a mRS score of 0 and 7 with a mRS score of 1. There were no procedure-related neurological complications. Our results show that local thrombolysis is a safe and effective treatment modality for patients suffering from progressive CVT.

Sign in / Sign up

Export Citation Format

Share Document