scholarly journals Immunohistochemical Expression of Stanniocalcin 2 in Colorectal Cancer: A Retrospective Egyptian Study

2022 ◽  
Vol 17 (1) ◽  
pp. 15-22
Author(s):  
Hala El-hanbuli ◽  
Rehab Galal ◽  
Mohammed Darweesh ◽  
Mohamed Elmahdi
Keyword(s):  
Colorectal Cancer ◽  
Immunohistochemical Expression ◽  
Stanniocalcin 2

scholarly journals Phosphorylated transducer and activator of transcription-3 (pSTAT3) immunohistochemical expression in paired primary and metastatic colorectal cancer

2021 ◽  
Vol 14 (2) ◽  
pp. 100996
Author(s):  
Esmeralda C. Marginean ◽  
Joanna Gotfrit ◽  
Horia Marginean ◽  
Daniel W. Yokom ◽  
Justin J. Bateman ◽  
...  
Keyword(s):  
Colorectal Cancer ◽  
Metastatic Colorectal Cancer ◽  
Immunohistochemical Expression ◽  
Transcription 3

Immunohistochemical expression (IHC) and microsatellite instability (MSI) analysis in families with clustering of colorectal cancer

2003 ◽  
Vol 124 (4) ◽  
pp. A55
Author(s):  
Andrea E. De Jong ◽  
Marjo Van Puijenbroek ◽  
Carli M.J. Tops ◽  
Juul Wijnen ◽  
Patrick F. Franken ◽  
...  
Keyword(s):  
Colorectal Cancer ◽  
Microsatellite Instability ◽  
Immunohistochemical Expression ◽  
Msi Analysis

Evaluation of immunohistochemical expression of survivin and its correlation with −31G/C gene polymorphism in colorectal cancer

2018 ◽  
Vol 52 (2) ◽  
pp. 82-89 ◽  
Author(s):  
Zahra Heidari ◽  
Hamidreza Mahmoudzadeh Sagheb ◽  
Asiyeh Hakimi ◽  
Bita Moudi
Keyword(s):  
Colorectal Cancer ◽  
Gene Polymorphism ◽  
Immunohistochemical Expression

Immunohistochemical expression of CDX2, β-catenin, and TP53 in inflammatory bowel disease-associated colorectal cancer

2011 ◽  
Vol 17 (1) ◽  
pp. 232-240 ◽  
Author(s):  
Camille Laurent ◽  
Magali Svrcek ◽  
Jean-François Flejou ◽  
Marie-Pierre Chenard ◽  
Bernard Duclos ◽  
...  
Keyword(s):  
Colorectal Cancer ◽  
Inflammatory Bowel Disease ◽  
Bowel Disease ◽  
Immunohistochemical Expression ◽  
Inflammatory Bowel

3041 POSTER Alpha(1, 6)fucosyltransferase immunohistochemical expression and the survival of patients with colorectal cancer

2007 ◽  
Vol 5 (4) ◽  
pp. 247-248
Author(s):  
L. Muinelo Romay ◽  
S. Villar Portela ◽  
E. Cuevas Álvarez ◽  
E. Gil Martín ◽  
A. Fernández Briera
Keyword(s):  
Colorectal Cancer ◽  
Immunohistochemical Expression

scholarly journals Expression of matrix metalloproteinases 2, 7 and 9 in patients with colorectal cancer

2014 ◽  
Vol 71 (1) ◽  
pp. 52-59 ◽  
Author(s):  
Elena Kostova ◽  
Maja Slaninka-Miceska ◽  
Nikola Labacevski ◽  
Krume Jakovski ◽  
Jasmina Trojachanec ◽  
...  
Keyword(s):  
Colorectal Cancer ◽  
Matrix Metalloproteinases ◽  
Tumor Invasion ◽  
Tumor Tissue ◽  
Serum Levels ◽  
Basement Membranes ◽  
Matrix Proteins ◽  
Immunohistochemical Expression ◽  
Preoperative Serum ◽  
Cell Expression

Background/Aim. Matrix metalloproteinases (MMPs) are perceived to play a key role in tumor invasion and metastasis by their capacity to degrade basement membranes and extracellular matrix proteins. The aim of this study was to investigate the expressions of MMP-2, MMP-7 and MMP-9 in tumor tissue and their relation to clinicopathologic features in patients with colorectal cancer. Methods. Specimens of resected colorectal cancer and surrounding normal tissue of 82 patients were immunohistochemically stained for MMP-2, MMP-7 and MMP-9. The results of immunohistochemical expression of MMPs were correlated with some clinical and pathologic parameters. Results. Immunohistochemical expression of MMP-2 was more frequent in the patients with higher preoperative serum levels of carcinoembryonic antigen (CEA) (p = 0.047), MMP-2 (p = 0.018), MMP-9 (p = 0.036) and in those with lymph node metastasis (p = 0.018) and the advanced stage of the disease (p = 0.046). Expression of MMP-7 was more frequent in the patients with elevated preoperative serum levels of: CEA (p = 0.012), MMP-7 (p = 0.036), MMP-9 (p = 0.023) and with deeply invasive neoplasms (p = 0.027). MMP-9 cell expression was in a positive correlation with elevated preoperative serum levels of: CEA (p = 0.013), MMP-2 (p = 0.012), MMP-9 (p = 0.018) and depth of CRC invasion, i.e. Tparameter (p = 0.027). Conclusion. Immunohistochemical expression of MMPs is a useful indicator of the disease development and progression in patients with colorectal cancer.

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