scholarly journals Place of Duloxetine in Concervative Treatment Women and Men with Stress Urinary Incontinence

Health of Man ◽  
2021 ◽  
pp. 77-84
Author(s):  
Viktor Gorovyi ◽  
Vladyslava Litvinets ◽  
Olena Gurzhenko

History of introduction of duloxetine in medical practice, mechanism of action and using of duloxetine in concervative treatment women and men with stress urinary incontinence are shown. Modern structure of external urethral sphincter in women and men was shown with increasing of sphincter tone under duloxetine influence. Duloxetine recommended by International Continent Society for initial treatment women with stress urinary incontinence but this drug gives only improvement of urine continence and quality of life with side effects. Duloxetine with connection with pelvic floor muscle training gives better results than using separately duloxetine and pelvic floor muscle training. Nausuea is the most frequency side symptom after using duloxetine. Results of own investigations were shown and indications for using duloxetine in women with stress urinary incontinence were summed up. The most positive results were obtained after combination of duloxetine with pelvic floor muscle training and electrostimulation of urethral sphincter. Duloxetine for treatment men with stress urinary incontinence after radical prostatectomy is only clinical tested. Estimation of efficacy of duloxetine in treatment men with stress urinary incontinence after open prostatectomy due to benign prostatic hyperplasia is needed.

2021 ◽  
Vol 10 (13) ◽  
pp. 2946
Author(s):  
Katarzyna Strojek ◽  
Magdalena Weber-Rajek ◽  
Agnieszka Strączyńska ◽  
Zuzanna Piekorz ◽  
Beata Pilarska ◽  
...  

Aim: The aim of this study was to assess the impact of pelvic floor muscle training (PMFT) in the treatment of stress urinary incontinence (SUI) in men after they received radical prostatectomy (RP). Methods: From November 2018 to September 2019, patients who underwent radical prostatectomy were assessed for eligibility. A total of 37 men were then randomly assigned to the experimental group (EG) and the control group (CG). The EG group received supervised exercise twice a week for 12 weeks, and the CG did not receive any intervention. To objectify the results obtained in both groups before and after the intervention, the authors assessed myostatin concentration. Moreover, the Expanded Prostate Cancer Index Composite (EPIC-26) was applied to assess the quality of life, and Beck’s Depression Inventory (BDI-II) was used to measure depression severity. Results: Study results demonstrated a statistically significant reduction of myostatin concentration in the EG following the treatment and no statistically significant differences in this parameter in the CG. In addition, a comparison of the EPIC-26 scores in the EG at the initial and final assessments revealed a statistically significant improvement in the quality of life in each domain. A comparison of the EPIC-26 scores in the CG at the initial and final assessments showed there is a statistically significant decline in quality of life in the “overall urinary problem” and “sexual” domain. A comparison of the BDI-II scores at the initial and final assessments showed a statistically significant decline in depressive symptoms in the EG and no statistically significant differences in the CG. Conclusions: PFMT is an effective treatment for urinary incontinence (UI) in men who received radical prostatectomy.


2021 ◽  
Vol 21 (1) ◽  
Author(s):  
Lotte Firet ◽  
Theodora Alberta Maria Teunissen ◽  
Rudolf Bertijn Kool ◽  
Lukas van Doorn ◽  
Manal Aourag ◽  
...  

Abstract Background Stress urinary incontinence (SUI) is common among women and affects their quality of life. Pelvic floor muscle training is an effective conservative therapy, but only a minority of women seek help. E-health with pelvic floor muscle training is effective and increases access to care. To implement an e-Health intervention in a sustainable way, however, we need to understand what determines adoption. The aim is to investigate the barriers and facilitators to adopting an e-Health intervention among Dutch women with stress urinary incontinence. Methods Semi-structured telephonic interviews were carried out among participants of the Dutch e-Health intervention for women with stress urinary incontinence. Women were purposively sampled. The ‘Fit between Individuals, Task and Technology’ (FITT) framework was used for both the data collection and data analysis, to gain a more in-depth insight into the adoption of the intervention. Results Twenty women were interviewed, mean age 51 years and mostly highly educated. The adoption of e-Health for women with SUI mainly depends on the interaction between users and e-Health, and users and pelvic floor muscle training exercises. Facilitators for the adoption were the preference for an accessible self-management intervention, having a strong sense of self-discipline and having the ability to schedule the exercises routinely. Women needed to possess self-efficacy to do this intervention independently. Barriers to the adoption of e-Health were personal circumstances restricting time for scheduling pelvic floor muscle training and lacking skills to perform the exercises correctly. Despite guidance by technical features several women remained uncertain about their performance of the exercises and, therefore, wanted additional contact with a professional. Conclusions For stress urinary incontinence e-Health is an appropriate option for a target audience. Use of the FITT framework clearly demonstrates the conditions for optimal adoption. For a subgroup it was a suitable alternative for medical care in person. For others it identified the need for further support by a health care professional. This support could be provided by improvements of technical features and incorporating modes for digital communication. The additional value of integration of the e-Health intervention in primary care might be a logical next step. Trial registration The study was prospectively registered in the Netherlands Trial Registry (NTR) NTR6956.


Author(s):  
María Zahara Pintos-Díaz ◽  
Paula Parás-Bravo ◽  
Cristina Alonso-Blanco ◽  
César Fernández-de-las-Peñas ◽  
María Paz-Zulueta ◽  
...  

Background: Urinary incontinence represents a complex problem which commonly affects women and influences their physical, mental and social wellbeing. The objective was to determine the effect of pelvic floor muscle training using a tampon as visual biofeedback. Methods: A non-randomized clinical trial involving 60 women >18 years of age, both with, and without, urinary incontinence. All women exercised with a program involving visual biofeedback using disposable tampons at home for three months. The compliance rate was 76.8 ± 24.1 An electromyographic assessment of the pelvic floor was performed and assessments of the impact of the exercise program. Results: 54.5% of women without incontinence and 81.6% of women incontinence reported improvements (p = 0.041). In both groups, there was increased quality life (p > 0.05). The women without incontinence experienced greater improvement in the quality of their sexual relations (Pre 6.8 ± 1.4–Post 7.2 ± 1.0). Conclusions: After the intervention, a high percentage of women showed a statistically significant improvement in their symptoms. The participants reported an increase in quality of life and the women without incontinence reported an improvement in quality of their sexual relations. Our findings suggest that visual BFB for training the PFM may be beneficial for women with or without incontinence.


2018 ◽  
Vol Volume 13 ◽  
pp. 1893-1898 ◽  
Author(s):  
Agnieszka Radzimińska ◽  
Magdalena Weber-Rajek ◽  
Agnieszka Strączyńska ◽  
Marta Podhorecka ◽  
Mariusz Kozakiewicz ◽  
...  

Author(s):  
Esther García-Sánchez ◽  
Vicente Ávila-Gandía ◽  
Javier López-Román ◽  
Alejandro Martínez-Rodríguez ◽  
Jacobo Á. Rubio-Arias

Pelvic floor muscle training is commonly used for urine loss. However, research studies have not determined which training load is the most effective for women with stress urinary incontinence (SUI). Moreover, none of the previous reviews or studies have described the total effectiveness of pelvic floor muscle training (PFMT) with an objective test such as the pad test. The objectives were to analyze the effectiveness of pelvic floor muscle training in women with SUI and to determine which training load produces the greatest adaptations for decreasing urine loss. The search was conducted in three databases (PubMed, Web of Science and Cochrane), for randomized controlled trials (RCTs) that evaluated the effects of PFMT. Studies were included if they met the following criteria: participants were women; were older than 18; had SUI; were treated with PFMT; and the assessments of the effects were measured with a pad test. Finally, 10 articles (293 women) analyzed the pad test in women with SUI who performed PFMT. The meta-analysis showed that PFMT, independent of the protocol used in the study, resulted in decreased urine loss in women suffering from SUI. However, for large effects, the program should last 6–12 weeks, with >3 sessions/week and a length of session <45 min.


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