Ferrous Gluconate Tablets

Keyword(s):  
2006 ◽  
Vol 136 (10) ◽  
pp. 2633-2637 ◽  
Author(s):  
Salvador Villalpando ◽  
Teresa Shamah ◽  
Juan A. Rivera ◽  
Yaveth Lara ◽  
Eric Monterrubio

2020 ◽  
Vol 2020 ◽  
pp. 1-8
Author(s):  
Noer Abyor Handayani ◽  
Elsa Anisa Krisanti ◽  
Sutrasno Kartohardjono ◽  
Kamarza Mulia

A proper understanding of the properties of iron could increase the effectiveness of programmes for alleviating iron deficiency. Recently, encapsulation has been considered an appropriate method for protecting iron from injurious reactions. However, several events may occur during encapsulation processes, including changes in the iron’s oxidation state. Oxidation of ferrous iron is not desirable since the intestines can only absorb iron in the ferrous form. In this study, a cyclic voltammetry method was applied to investigate the likelihood of ferrous gluconate oxidation for the preparation of chitosan-tripolyphosphate microparticles. Then, the electrochemical properties of ferrous gluconate were confirmed experimentally. The oxidation rate of ferrous gluconate is also discussed in this paper. All the experimental solutions were formulated in detail to produce conditions similar to those of microparticle production. Cyclic voltammetry analysis was conducted using a configuration of three electrodes connected to an electrochemical analyser. Graphite, platinum wire, and Ag/AgCl were employed as the auxiliary, working, and reference electrodes, respectively. The cyclic voltammetry results show that the observed potential for each anodic peak shifted negatively in the presence of chitosan and sodium tripolyphosphate. Moreover, the rate of ferrous oxidation tended to increase during 75 min of experiments due to the presence of chitosan and sodium tripolyphosphate. These behaviours indicate the transformation of ferrous iron to ferric iron during iron microparticle preparation. Furthermore, these findings suggest that spray drying is a preferable method to minimise the oxidation reaction.


2019 ◽  
Vol 11 (3) ◽  
pp. 172-177
Author(s):  
Natassa Pippa ◽  
Nikolaos Naziris ◽  
Nikolaos Fikioris ◽  
Costas Demetzos
Keyword(s):  

JAMA ◽  
1963 ◽  
Vol 186 (13) ◽  
Author(s):  
F. Henderson ◽  
T. J. Vietti ◽  
Elmer B. Brown

2006 ◽  
Vol &NA; (1090) ◽  
pp. 12
Author(s):  
&NA;
Keyword(s):  

e-GIGI ◽  
2021 ◽  
Vol 9 (2) ◽  
pp. 181
Author(s):  
Sarah Mersil

Abstract: Studies in Indonesia stated that the main cause of nutritional anemia in adolescents is due to lack of iron intake, which is called iron deficiency anemia. One of its oral manifestations is stomatitis. Thrombocytosis is also found in iron deficiency anemia. We reported a case of a 22-year-old female patient with complaints of stomatitis and further examination showed the occurrence of iron deficiency anemia and thrombocytosis. The patient was instructed to maintain good diet containing meat, vitamin C-rich vegetables and fruits, have good sleep pattern, take care of her oral health, and not to force herself to overwork. Triamcinolone acetonide in ora base 0.1% was applied on the lesion by using cotton bud after meal and before bedtime until the lesion disappeared or became painless. The patient was referred to an internist for further examination. After two weeks, the lesion had disappeared, and there was no new lesion. However, the patient had not checked to the internist, therefore, ferrous gluconate 250 mg twice daily was given to her for 30 days. In conclusion, the patient was diagnosed as stomatitis aphthosa as an oral manifestation of iron deficiency anemia associated with secondary thrombocytosis.Keywords: stomatitis, iron deficiency anemia, thrombocytosis Abstrak: Penelitian di Indonesia menyatakan bahwa penyebab utama terjadinya anemia gizi pada remaja ialah kurangnya asupan zat besi, yang disebut anemia defisiensi zat besi. Salah satu manifestasi oralnya ialah stomatitis. Kondisi trombositosis juga ditemukan pada anemia defisiensi zat besi. Kami melaporkan kasus seorang perempuan berusia 22 tahun dengan keluhan stomatitis dan hasil pemeriksaan penunjang menunjukkan anemia defisiensi zat besi dan trombositosis. Pasien diinstruksikan untuk menjaga pola makan yang baik dengan mengonsumsi daging serta buah dan sayuran mengandung vitamin C, tidur serta istirahat yang cukup, tidak memaksakan diri secara berlebihan, serta menjaga kebersihan mulut. Diberikan obat oles yaitu triamcinolone acetonide in orabase 0,1% untuk dioles pada lesi menggunakan cotton bud sehabis makan dan sebelum tidur sampai lesi sembuh atau tidak sakit lagi. Pasien dirujuk ke spesialis penyakit dalam untuk tindak lanjut dari kondisi sistemiknya. Kontrol setelah dua minggu sariawan sudah hilang, tidak muncul sariawan baru. Pasien belum ke dokter spesialis penyakit dalam untuk memeriksa kondisi anemia yang dideritanya. Oleh karena itu diberikan ferrous gluconate 250 mg dua kali sehari selama 30 hari. Simpulan kasus ini ialah suatu stomatitis sebagai salah satu manifestasi oral pada anemia defisiensi besi yang disertai trombositosis sekunder.Kata kunci: stomatitis, anemia defisiensi zat besi, trombositosis


Author(s):  
Nergis Kaya

In completed research, ferrous gluconate -a food additive- used to preserve black color to prevent discoloration during storage in ripe black olives, and Allium cepa L. species. A. cepa L. roots were treated with different doses of ferrous gluconate. The effective concentration EC50 (0.068 g/l) was determined. A. cepa root tips were treated with EC50/2 (0.034 g/l), EC50 (0.068 g/l), 2XEC50 (0.136 g/l) dose for 24, 48, 72 hours, and afterward, the root tips were prepared for observation under the light microscope according to the method of preparing mitotic preparation. Chromosomal abnormality index (CAI) and genotoxic effect of ferrous gluconate in A. cepa root tip cells were determined. Repeated measurement ANOVA and TUKEY multiple comparison tests were used to investigate the effect of time and dose together on genotoxicity. C-mitosis, polyploidy, polar shifting in anaphase, polar shifting in telophase, equatorial plate shifting, laggard chromosome was observed by microscope. The highest CAI (70.16±4.85) was observed at 72h for 2XEC50 dose. Chromosomal aberration is also observed in control group. While the most common chromosomal aberration is determined as C-mitosis; The least observed chromosomal aberration is determined as polyploidy. Research results revealed that ferrous gluconate has a genotoxic effect on the root tip of A. cepa.


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