Seroimmunological affiliation of African swine fever virus isolated in the Russian Federation

2011 ◽  
Vol 37 (5) ◽  
pp. 427-429 ◽  
Author(s):  
V. M. Balyshev ◽  
Yu. F. Kalantaenko ◽  
M. V. Bolgova ◽  
E. Yu. Prodnikova
2020 ◽  
Vol 70 (1) ◽  
pp. 58-70
Author(s):  
Mikhail Vlasov ◽  
Almaz Imatdinov ◽  
Ilya Titov ◽  
Nikola Vasković ◽  
Valentina Lyska ◽  
...  

AbstractThe article presents the results of a comparative study of the biological, molecular and genetic characteristics of African swine fever virus (ASFV) isolates, obtained from domestic pigs and wild boars in the Russian Federation and South Ossetia from 2016 to 2018. The studied isolates caused the death of pigs manifesting, as a rule, signs of an acute or subacute form of the disease when using various methods of infection including intramuscular, direct contact, intranasal and oral routes. The virus was hemadsorbing, belonging to serotype 8 and genotype II, and accumulated in the blood with a titer of 6.5 to 7.5 lg HAU50/cm3. The ASFV isolates circulating in the central region of Russia were found to have an insertion of 10 base pairs in the intergenic region I73R/I329L. However, the ASFV isolated in the Irkutsk region and South Ossetia, as well as Georgia 2007/1 (FR682468.1), lacked this insertion.


2016 ◽  
Vol 91 (6) ◽  
Author(s):  
Ana Luisa Reis ◽  
Chris Netherton ◽  
Linda K. Dixon

ABSTRACT African swine fever is an acute hemorrhagic disease of pigs. Extensive recent spread in the Russian Federation and Eastern Europe has increased the risk to global pig production. The virus is a large DNA virus and is the only member of the Asfarviridae family. In pigs, the virus replicates predominantly in macrophages. We review how the virus overcomes the barriers to replication in the macrophage and the virus mechanism to inhibit key host defense pathways.


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