scholarly journals Dosimetric Comparison and Clinical Toxicity in Cervical Cancer Patients Treated with Intensity- Modulated and Three-Dimensional Conformal Radiotherapy: Real-World Data

2020 ◽  
Vol 5 (4) ◽  
Keyword(s):  
Cervical Cancer ◽  
Cancer Patients ◽  
Real World ◽  
Three Dimensional ◽  
Conformal Radiotherapy ◽  
Real World Data ◽  
Dosimetric Comparison ◽  
Intensity Modulated ◽  
Clinical Toxicity ◽  
Three Dimensional Conformal Radiotherapy

Dosimetric analysis of intensity-modulated radiotherapy and three-dimensional conformal radiotherapy for chest wall irradiation in breast cancer patients

2015 ◽  
Vol 15 (1) ◽  
pp. 30-37 ◽  
Author(s):  
Mehlam Kausar ◽  
Om Prakash Gurjar ◽  
Priyusha Bagdare ◽  
Krishna Lal Gupta ◽  
Virendra Bhandari ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Cancer Patients ◽  
Chest Wall ◽  
Three Dimensional ◽  
Intensity Modulated Radiotherapy ◽  
Conformal Radiotherapy ◽  
Breast Cancer Patients ◽  
Intensity Modulated ◽  
Significant Difference ◽  
Three Dimensional Conformal Radiotherapy

AbstractBackgroundFor chest wall irradiation in breast cancer patients, three-dimensional conformal radiotherapy (3DCRT) and intensity-modulated radiotherapy (IMRT) have made tremendous changes in treatment delivery.PurposeThe purpose of this study is to compare the dosimetric parameters in IMRT and 3DCRT plans.Materials and methodsIMRT and 3DCRT plans were generated for 25 randomly selected postmastectomy breast cancer patients. The prescribed dose (PD) was 50 Gray (Gy) in 25 fractions (#) at the rate of 2 Gy/# with 5#/week. Dose volume histogram was evaluated for planning target volume (PTV) coverage and dose to organs at risk (OARs). All the dosimetric parameters were compared using unpaired student’s t-test.ResultsPTV coverage was significantly better in IMRT, although the 90% of PTV was well covered by 90% of PD in all plans by both the techniques. Homogeneity index and conformity index were better in IMRT. V5 Gy and Dmean of contralateral lung, contralateral breast and heart (right side chest wall cases) were found to be lesser in 3DCRT compared with that in IMRT. However, there was no significant difference in V20 Gy of ipsilateral lung and V25 Gy of heart (left side chest wall cases) in all the plans by both the techniques.ConclusionAdequate target coverage was achieved by both the techniques, however, dose to OARs were lesser in 3DCRT plans as compared with that in IMRT plans. Thus, it can be concluded that 3DCRT is as efficient as IMRT for the chest wall irradiation.

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