Psychologic Factors in Peptic Ulcer Disease and Irritable Bowel Syndrome: A Review of the Literature on the Role of Psychologic Factors in (Two) Gastrointestinal Diseases

1989 ◽  
Vol 24 (sup171) ◽  
pp. 126-132
Author(s):  
J. J. Nicolai
1999 ◽  
Vol 54 (4) ◽  
pp. 131-134 ◽  
Author(s):  
Adriana Vaz Safatle-Ribeiro ◽  
Ulysses Ribeiro Júnior ◽  
Angelita Habr-Gama ◽  
Joaquim J. Gama-Rodrigues

Double pylorus is an unusual condition in which a double communication between the gastric antrum and the duodenal bulb occurs. It may be congenital, or it may be acquired complication of peptic ulcer disease. We present a case of double pylorus in a gentleman with epigastric pain and previous history of peptic ulcer disease. The relationship between Helicobacter pylori and this disease was assessed. A review of the literature, the role of associated diseases and the role of H. pylori are discussed.


2021 ◽  
Vol 12 (1) ◽  
Author(s):  
Yeda Wu ◽  
Graham K. Murray ◽  
Enda M. Byrne ◽  
Julia Sidorenko ◽  
Peter M. Visscher ◽  
...  

AbstractGenetic factors are recognized to contribute to peptic ulcer disease (PUD) and other gastrointestinal diseases, such as gastro-oesophageal reflux disease (GORD), irritable bowel syndrome (IBS) and inflammatory bowel disease (IBD). Here, genome-wide association study (GWAS) analyses based on 456,327 UK Biobank (UKB) individuals identify 8 independent and significant loci for PUD at, or near, genes MUC1, MUC6, FUT2, PSCA, ABO, CDX2, GAST and CCKBR. There are previously established roles in susceptibility to Helicobacter pylori infection, response to counteract infection-related damage, gastric acid secretion or gastrointestinal motility for these genes. Only two associations have been previously reported for duodenal ulcer, here replicated trans-ancestrally. The results highlight the role of host genetic susceptibility to infection. Post-GWAS analyses for PUD, GORD, IBS and IBD add insights into relationships between these gastrointestinal diseases and their relationships with depression, a commonly comorbid disorder.


2001 ◽  
Vol 120 (5) ◽  
pp. A136-A137
Author(s):  
K TSAMAKIDES ◽  
E PANOTOPOULOU ◽  
D DIMITROULOPOULOS ◽  
M CHRISTOPOULO ◽  
D XINOPOULOS ◽  
...  

2020 ◽  
Vol 112 (5) ◽  
pp. S25
Author(s):  
Olubode A. Olufajo ◽  
Delaram J. Taghipour ◽  
Gezzer Ortega ◽  
Cheryl K. Zogg ◽  
Edward E. Cornwell ◽  
...  

2020 ◽  
Vol 112 (5) ◽  
pp. S38
Author(s):  
Olubode A. Olufajo ◽  
Delaram J. Taghipour ◽  
Gezzer Ortega ◽  
Cheryl K. Zogg ◽  
Edward E. Cornwell ◽  
...  

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