Response to “Role of surgical versus endovascular embolectomy for the treatment of acute large vessel occlusion”

2014 ◽  
Vol 28 (3) ◽  
pp. 431-432 ◽  
Author(s):  
Tomohiro Inoue ◽  
Akira Tamura ◽  
Isamu Saito ◽  
Kazuo Tsutsumi ◽  
Nobuhito Saito
2020 ◽  
Vol 29 (10) ◽  
pp. 105172
Author(s):  
Omar Hussein ◽  
Ahmed Abd Elazim ◽  
Khalid Sawalha ◽  
Smeer Salam ◽  
Kasser Saba ◽  
...  

Author(s):  
Nan N. Jiang ◽  
Wei Wu ◽  
Crystal Fong ◽  
Demetrios J. Sahlas ◽  
Ramiro Larrazabal

2021 ◽  
pp. 1-8
Author(s):  
Riccardo Di Iorio ◽  
Fabio Pilato ◽  
Iacopo Valente ◽  
Andrea Laurienzo ◽  
Simona Gaudino ◽  
...  

<b><i>Introduction:</i></b> We sought to verify the predicting role of a favorable profile on computed tomography perfusion (CTP) in the outcome of patients with acute ischemic stroke (AIS) due to large vessel occlusion (LVO) undergoing effective mechanical thrombectomy (MT). <b><i>Methods:</i></b> We retrospectively enrolled 25 patients with AIS due to LVO and with a CTP study showing the presence of ischemic penumbra who underwent effective MT, regardless of the time of onset. The controls were 25 AIS patients with overlapping demographics and clinical and computed tomography angiography features at admission who had undergone successful MT within 6 h from onset and without a previous CTP study. The outcome measure was the modified Rankin Scale (mRS) score at 90 days. <b><i>Results:</i></b> Sixty-four percent of the study patients had an mRS score of 0–1 at 90 days versus 12% of the control patients (<i>p</i> &#x3c; 0.001). Patients of the study group had a more favorable distribution of disability scores (median mRS [IQR] score of 0 [0–2] vs. 2 [2–3]). Multivariate analysis showed that the selection of patients based on a favorable CTP study was strongly associated (<i>p</i> &#x3c; 0.001) with a better neurological outcome. <b><i>Conclusions:</i></b> In our small-sized and retrospective study, the presence of ischemic penumbra was associated with a better clinical outcome in patients with AIS due to LVO after MT. In the future, a larger and controlled study with similar criteria of enrollment is needed to further validate the role of CTP in patient selection for MT, regardless of the time from the onset of symptoms.


2020 ◽  
pp. 1-6
Author(s):  
Panagiotis Papanagiotou ◽  
Guillermo Parrilla ◽  
L. Creed Pettigrew

This commentary will focus on the role of thrombectomy for the treatment of embolic stroke during the 2019 novel coronavirus disease (COVID-19). We will begin with review of recently promulgated guidelines for use of thrombectomy in COVID-19-associated stroke. We will then survey the reported experience of thrombectomy applied to treatment of large-vessel occlusion (LVO) stroke in COVID-19. We will conclude by discussing unusual challenges confronted by neuro-interventionalists seeking to perform thrombectomy in COVID-19 patients with acute LVO stroke.


2018 ◽  
pp. 94-100
Author(s):  
Aaron Farney

Acute ischemic strokes have significant morbidity and mortality, particularly when they involve a large vessel occlusion. This case reviews the prehospital presentation of a patient with a large vessel occlusion stroke, the critical role prehospital personnel have in recognizing a stroke, determining the most appropriate facility, and identifying the most appropriate transport modality. Approaches to managing the unconscious patient’s airway are discussed, with particular attention to the effects intubation may have on intracranial pressure. As large vessel occlusion ischemic strokes have a therapeutic option not previously available, the role of prehospital identification and destination determination is even more critical ,and this case reviews those considerations.


2019 ◽  
pp. 1357633X1986719 ◽  
Author(s):  
Haidar Moustafa ◽  
Kristian Barlinn ◽  
Alexandra Prakapenia ◽  
Simon Winzer ◽  
Johannes Gerber ◽  
...  

Introduction Recent exploratory analysis suggested comparable outcomes among stroke patients undergoing endovascular therapy (EVT) for anterior circulation large vessel occlusion, whether selected via the telestroke network or admitted directly to an EVT-capable centre. We further studied the role of telemedicine in selection of ischaemic stroke patients potentially eligible for EVT. Methods We prospectively included consecutive ischaemic stroke patients with anterior circulation large vessel occlusion who underwent EVT at our neurovascular centre (January 2016 to March 2018). We compared safety and efficacy including symptomatic intracerebral haemorrhage (sICH), successful reperfusion (mTICI 2b/3), 90-day favourable outcome (mRS ≤ 2) and 90-day survival between patients transferred from telestroke hospitals and patients directly admitted. Results Of 280 potentially EVT-eligible patients, 72/129 (56%) telestroke and 91/151 (60%) direct admissions eventually underwent EVT (age 76 (66–82) years, median (interquartile range), 46% men, NIHSS score 17 (13–20)). Telestroke patients had larger pre-EVT infarct cores (ASPECTS: 7 (6–8) vs. 8 (7–9); p < 0.0001) and shorter door-to-groin puncture times (71 (56–84) vs. 101 (79–133) min; p < 0.0001) than directly admitted patients. sICH (2.8% vs. 1.1%; p = 0.58), successful reperfusion (81% vs. 77%; p = 0.56), 90-day favourable outcome (25% vs. 29%; p = 0.65) and 90-day survival (73% vs. 67%; p = 0.39) rates were comparable among telestroke and direct admissions. Discussion Our data underpins the important role of telemedicine in identifying acute ischaemic stroke patients lacking immediate access to EVT-capable stroke centres. Stroke patients selected via telemedicine and those directly admitted had comparable chances of favourable outcomes after EVT for large vessel occlusion.


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