Effect of clonidine on post-traumatic memory deficits

Brain Injury ◽  
1990 ◽  
Vol 4 (2) ◽  
pp. 209-211 ◽  
Author(s):  
Floyd L. McIntyre ◽  
Philip Gasquoine
2006 ◽  
Vol 37 (03) ◽  
Author(s):  
S Petrova ◽  
K Roll ◽  
C Betzler ◽  
S Lütjen ◽  
H Holthausen

2021 ◽  
pp. 175069802098201
Author(s):  
Golan Moskowitz

Queer and trauma theory both concern internal experiences that challenge normative social frameworks. Considering the roles of queerness within trauma and memory studies opens interpretive pathways for otherwise discredited or inaccessible meanings. It also relates survivors’ receding knowledge to those currently “queered” or endangered. With a focus on childhood and mother-child relationships, this article maps intersections of memory studies, queer theory, and trauma theory, applying subsequent insights to an “autotheoretical” analysis of the author’s own transnational, post-Holocaust family across four generations. It explores the possibility through queer studies of excavating new post-traumatic meanings and relating those meanings to present contexts.


2008 ◽  
Vol 193 (3) ◽  
pp. 254-255 ◽  
Author(s):  
Jennifer Wild ◽  
Ruben C. Gur

SummaryPost-traumatic stress disorder (PTSD) is often associated with verbal memory deficits, which could influence treatment outcome. We assessed neuropsychological functioning in individuals with PTSD and their response to cognitive– behavioural therapy (CBT). Treatment non-responders had significantly poorer performance on measures of verbal memory compared with responders and demonstrated narrative encoding deficits. Differences were not explained by IQ, performance on tasks of attention, initial PTSD severity, depression, time since trauma, or alcohol/substance misuse. Verbal memory deficits seem to diminish the effectiveness of CBT and should be considered in its implementation.


2021 ◽  
Author(s):  
Eline Voorendonk ◽  
Thomas Meyer ◽  
Sascha B. Duken ◽  
Vanessa van Ast

Intrusive and distressing memories are at the core of post-traumatic stress disorder (PTSD). Since cardiorespiratory fitness (CRF) has been linked with improved mental health, emotion regulation, and memory function, CRF may, by promoting these capabilities, protect against the development of intrusions after trauma. We investigated this idea in 115 healthy individuals, using a trauma film to induce intrusions. As potential mediators, we assessed indices of pre-trauma mental health such as heart rate variability, subjective and psychobiological peri-traumatic responses, and memory. Critically, results showed that higher CRF was related to fewer intrusions, but no mediators emerged of the CRF-intrusion relationship. These results indicate that individuals displaying higher CRF are less prone to develop traumatic memory intrusions. This suggests that promoting fitness prior to possible trauma exposure may provide a useful strategy to boost resilience against the development of debilitating re-experiencing symptoms of PTSD.


2021 ◽  
pp. 153-164
Author(s):  

In The Sea (2005) and The Gathering (2007), John Banville and Anne Enright incorporate modernist and postmodernist intertextuality into accounts of bereavement. While the shattered existence of the protagonists is seemingly devoid of religious belief, they mobilize the palimpsestic immemorial past of mythological and fairy-tale intertexts to make sense of broken realities. The narrators’ self-portraits and invocations of lost people and places, oscillating between reminiscence and mythification, underscore postmodernism’s play with canonical stories. Both authors use mythological syncretism to express their characters’ quest for meaning: while Greek, Egyptian and Norse gods invade The Sea’s modern-day “Atlantis” (132), The Gathering is peopled with subverted Christian and Irish figures. However, rather than restoring coherence, myth and fairy-tale tropes are suffused with desperate irony, and the magic spell woven by mythological counterpoints turns out to be a post-traumatic, grimacing reflection of the characters’ troubled psyches, or an obfuscating screen. By interweaving and debunking seminal myths and tales, Banville and Enright give life to personal myths that bespeak the characters’ deep-seated sense of loss and disenchantment. The reader is thus left wondering if, by filling the gaps of post-traumatic memory with mythological rewritings, these defamiliarizing narratives of bereavement convey potential solace or reinforce their protagonists’ post-traumatic loss of landmarks.


2020 ◽  
Vol 6 (2) ◽  
pp. 72
Author(s):  
Siti Kurniati Rasad ◽  
Achmad Munjid

This article investigates how the trauma of 9/11 tragedy affects the lives of the characters in DeLillo’s Falling Man and shows how the trauma of 9/11 portrayed in the novel reflects American collective trauma. This investigation is qualitative research utilizing memory and trauma as the theoretical framework. The discussion in this article reveals that individual experience the trauma of 9/11 tragedy differs from one person to another. While other characters go through their mourning successfully, the main character in the novel becomes a perennial mourner and is ceaselessly haunted by his traumatic memory due to constant avoidance from his trauma. His continuous externalization of his trauma causes him to focus on the external threats and becomes a paranoiac. On a societal level, American society is also perpetually mourning and is haunted by post-traumatic paranoia continuously. American exceptionalism, biased orientalist perspective about the orient, and alleged prolonged quasi war between Islam and the west have framed the collective experience of the trauma in binary opposite narrative of a good versus evil war. The collective trauma perpetuates and many policies are born out of their paranoia.Keywords: 9/11 tragedy; memory; mourning; post-traumatic paranoia; trauma


2020 ◽  
Author(s):  
Victor M. Tang ◽  
Kathleen Trought ◽  
Kristina M. Gicas ◽  
Mari Kozak ◽  
Sheena A. Josselyn ◽  
...  

AbstractIntroductionPost-traumatic Stress Disorder (PTSD) often does not respond to available treatments. Memories are vulnerable to disruption during reconsolidation, and electroconvulsive therapy (ECT) has amnestic effects. We sought to exploit this phenomenon as a potential treatment for PTSD with a clinical trial of patients with PTSD receiving ECT.MethodsTwenty-eight participants with severe depression with comorbid PTSD referred for ECT treatment were randomly assigned to reactivation of a traumatic or non-traumatic memory using script driven imagery prior to each ECT treatment. Primary outcomes were change in scores on the Modified PTSD Symptom Scale - Self Report (MPSS-SR) and the Clinician-Administered PTSD Scale for DSM-5 (CAPS-5). Assessments were completed by blinded raters. Secondary outcomes included a comparison of the change in heart rate while listening to the script.ResultsTwenty-five patients who completed a post-ECT assessment were included in the analysis. No significant group differences were found in the MPSS-SR or CAPS-5 scores from pre-ECT to post-ECT or 3-month follow-ups. However, both groups improved at post-ECT and 3-month follow up. Partial eta squared estimates of effect size showed large effect sizes for all outcomes (η2 > 0.13). Changes in heart rate were not significantly different between groups or over time.ConclusionsIn this RCT, ECT paired with pre-treatment traumatic memory reactivation was not more effective for treating PTSD symptoms than ECT alone. While our primary hypothesis was not supported, our data provides further support for the efficacy of ECT for improving symptoms of PTSD with comorbid depression.ClinicalTrials.govhttps://clinicaltrials.gov/ct2/show/NCT04027452Identifier: NCT04027452


2018 ◽  
Vol 70 (4) ◽  
pp. 392-407
Author(s):  
Yuri Corrigan

Abstract This essay explores Donna Tartt’s adaptation of Fyodor Dostoevsky’s novels The Adolescent, The Idiot, and The Brothers Karamazov in The Goldfinch as a guide to understanding Dostoevsky’s unorthodox and theologically inflected theory of trauma. The essay argues that both authors approach traumatic memory through the ancient folkloric archetype of the “external soul” (the inner essence displaced into external objects for safekeeping) and conceive of the healing process as the attempt to bring the externalized soul—and its unwanted memories—back into the body. This motif allows both writers to reimagine the concept of the soul in modern secular terms: in Tartt’s conception of post-traumatic “soul loss” as a critical stage in the moral and aesthetic education of the self, and in Dostoevsky’s view of wounded memory as opening up the self to the more expansive, overwhelming trauma of religious experience. Tartt’s use of Dostoevsky in The Goldfinch underscores the Russian author’s value to contemporary trauma studies as an alternative to the prevailing canon.


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