Influence of Substrate Nature and Immobilization of Implanted Dentin Matrix Components During Induction of Reparative Dentinogenesis

Aluminum, gold, silver, nickel, silicon, glass, silicon dioxide, silicon nitride and so on, employed as bulk materials or thin films, represent the most commonly used materials for MEMS applications within the automotive, biomedicine, spatial industries and so forth. This work is a study regarding the influence of substrate nature on the mechanical properties of silver thin films elaborated for MEMS devices. The silver thin films were obtained by thermal evaporation method under vacuum protection on three different substrates. Glass, plastic (polycarbonate) and steel (C45) respectively are the materials used for the substrates. Further, atomic force microscopy investigations were performed on the elaborated samples in order to characterize them at a nanoscale and establish substrates influence. The Young’s modulus, nanohardness and roughness of the researched samples are the characteristics that were determined. A significant influence of substrate nature on the properties mentioned above for the studied silver thin films was marked out.

Download Full-text

Influence of substrate nature on the d.c.-glow discharge induced nucleation of diamond

Diamond and Related Materials ◽

10.1016/s0925-9635(98)00303-3 ◽

1999 ◽

Vol 8 (2-5) ◽

pp. 132-138 ◽

Cited By ~ 12

Author(s):

I. Gouzman ◽

R. Shima-Edelstein ◽

G. Comtet ◽

L. Hellner ◽

G. Dujardin ◽

...

Keyword(s):

Glow Discharge ◽

Influence Of Substrate ◽

Substrate Nature

Download Full-text

Influence of Substrate Nature and Annealing on Electro-Optical Properties of ZnO Thin Films

10.1063/1.2733132 ◽

2007 ◽

Author(s):

Felicia Iacomi ◽

C. Baban ◽

Nicoleta Iftimie ◽

Petronela Prepelita ◽

D. Luca

Keyword(s):

Thin Films ◽

Optical Properties ◽

Zno Thin Films ◽

Influence Of Substrate ◽

Substrate Nature

Download Full-text

Thin Tantalum Film Electrodeposition from an Ionic Liquid - Influence of Substrate Nature, Electrolyte Temperature and Electrochemical Parameters on Deposits’ Quality

Journal of The Electrochemical Society ◽

10.1149/1945-7111/ac1697 ◽

2021 ◽

Author(s):

Maguy Nahra ◽

Lenka Svecova ◽

Nicolas Sergent ◽

Eric Chainet

Keyword(s):

Ionic Liquid ◽

Electrolyte Temperature ◽

Electrochemical Parameters ◽

Influence Of Substrate ◽

Substrate Nature

Download Full-text

Dentinogenic effects of extracted dentin matrix components digested with matrix metalloproteinases

Scientific Reports ◽

10.1038/s41598-018-29112-3 ◽

2018 ◽

Vol 8 (1) ◽

Cited By ~ 13

Author(s):

Motoki Okamoto ◽

Yusuke Takahashi ◽

Shungo Komichi ◽

Paul R. Cooper ◽

Mikako Hayashi

Keyword(s):

Wound Healing ◽

Matrix Metalloproteinases ◽

Biological Effects ◽

Organic Matrix ◽

Bioactive Molecules ◽

Cell Functions ◽

Dentin Matrix ◽

Matrix Components

Abstract Dentin is primarily composed of hydroxyapatite crystals within a rich organic matrix. The organic matrix comprises collagenous structural components, within which a variety of bioactive molecules are sequestered. During caries progression, dentin is degraded by acids and enzymes derived from various sources, which can release bioactive molecules with potential reparative activity towards the dentin-pulp complex. While these molecules’ repair activities in other tissues are already known, their biological effects are unclear in relation to degradation events during disease in the dentin-pulp complex. This study was undertaken to investigate the effects of dentin matrix components (DMCs) that are partially digested by matrix metalloproteinases (MMPs) in vitro and in vivo during wound healing of the dentin-pulp complex. DMCs were initially isolated from healthy dentin and treated with recombinant MMPs. Subsequently, their effects on the behaviour of primary pulp cells were investigated in vitro and in vivo. Digested DMCs modulated a range of pulp cell functions in vitro. In addition, DMCs partially digested with MMP-20 stimulated tertiary dentin formation in vivo, which exhibited a more regular tubular structure than that induced by treatment with other MMPs. Our results indicate that MMP-20 may be especially effective in stimulating wound healing of the dentin-pulp complex.

Download Full-text