The Chemiluminescence Assay of Lipid Peroxidation Products in Human Blood Plasma Lipoproteins

1994 ◽  
Vol 20 (5) ◽  
pp. 279-288 ◽  
Author(s):  
Elena Driomina ◽  
Igor Polnikov ◽  
Victor Sharov ◽  
Ofelia Azizova ◽  
Yury Vladimirov
Keyword(s):  
Lipid Peroxidation ◽  
Blood Plasma ◽  
Human Blood ◽  
Plasma Lipoproteins ◽  
Human Blood Plasma ◽  
Lipid Peroxidation Products ◽  
Chemiluminescence Assay ◽  
Blood Plasma Lipoproteins

Mechanisms of lipid peroxidation in human blood plasma: a kinetic approach

1997 ◽  
Vol 88 (2) ◽  
pp. 83-96 ◽  
Author(s):  
Barbara Karten ◽  
Ulrike Beisiegel ◽  
Günther Gercken ◽  
Anatol Kontush
Keyword(s):  
Lipid Peroxidation ◽  
Blood Plasma ◽  
Human Blood ◽  
Kinetic Approach ◽  
Human Blood Plasma

Evaluation of an isoluminol chemiluminescence assay for the detection of hydroperoxides in human blood plasma

1988 ◽  
Vol 175 (1) ◽  
pp. 120-130 ◽  
Author(s):  
Balz Frei ◽  
Yorihiro Yamamoto ◽  
Daniel Niclas ◽  
Bruce N. Ames
Keyword(s):  
Blood Plasma ◽  
Human Blood ◽  
Human Blood Plasma ◽  
Chemiluminescence Assay

scholarly journals Gas phase oxidants of cigarette smoke induce lipid peroxidation and changes in lipoprotein properties in human blood plasma. Protective effects of ascorbic acid

1991 ◽  
Vol 277 (1) ◽  
pp. 133-138 ◽  
Author(s):  
B Frei ◽  
T M Forte ◽  
B N Ames ◽  
C E Cross
Keyword(s):  
Lipid Peroxidation ◽  
Ascorbic Acid ◽  
Blood Plasma ◽  
Gas Phase ◽  
Cigarette Smoke ◽  
Human Blood ◽  
Biological Fluids ◽  
Human Blood Plasma ◽  
Lipid Hydroperoxides ◽  
Protein Thiols

Cigarette smoke (CS) is known to contain a large number of oxidants. In order to assess the oxidative effects of CS on biological fluids, we exposed human blood plasma to filtered (gas phase) and unfiltered (whole) CS, and determined the rate of utilization of endogenous antioxidants in relation to the appearance of lipid hydroperoxides. Lipid peroxidation was measured with a specific and sensitive assay that can detect lipid hydroperoxides at plasma levels as low as 10 nM. We found that exposure of plasma to the gas phase of CS, but not to whole CS, induces lipid peroxidation once endogenous ascorbic acid has been oxidized completely. In addition, CS exposure caused oxidation of plasma protein thiols and albumin-bound bilirubin, whereas uric acid and alpha-tocopherol were not consumed at significant rates. In plasma exposed to the gas phase of CS, low-density lipoprotein exhibited slightly increased electrophoretic mobility, but there was no apparent degradation of apolipoprotein B. Our results support the concept of an increased vitamin C utilization in smokers, and suggest that lipid peroxidation induced by oxidants present in the gas phase of CS leads to potentially atherogenic changes in lipoproteins.

Dual Layer Mixed Matrix Hollow Fiber Membranes for Outside-In Filtration of Human Blood Plasma

2020 ◽  
Author(s):  
O.E.M. ter Beek ◽  
M.K. van Gelder ◽  
C. Lokhorst ◽  
D.H.M. Hazenbrink ◽  
B.H. Lentferink ◽  
...  
Keyword(s):  
Blood Plasma ◽  
Human Blood ◽  
Hollow Fiber ◽  
Human Blood Plasma ◽  
Hollow Fiber Membranes ◽  
Mixed Matrix ◽  
Fiber Membranes
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