A herbal medicine, saikokaryukotsuboreito, improves serum testosterone levels and affects sexual behavior in old male mice

2014 ◽  
Vol 18 (2) ◽  
pp. 106-111 ◽  
Author(s):  
Zhi Jun Zang ◽  
Su Yun Ji ◽  
Wang Dong ◽  
Ya Nan Zhang ◽  
Er Hong Zhang ◽  
...  
Keyword(s):  
Sexual Behavior ◽  
Herbal Medicine ◽  
Serum Testosterone ◽  
Male Mice ◽  
Testosterone Levels

Overweight male juvenile rats exhibit decreases in sexual behavior and serum testosterone levels and an increase in TNF-α levels in adulthood.

2016 ◽  
Vol 9 (2) ◽  
pp. 188-197 ◽  
Author(s):  
Daclé J. Macrini ◽  
Leoni V. Bonamin ◽  
Elizabeth Teodorov ◽  
Thiago B. Kirsten ◽  
Cideli P. Coelho ◽  
...  
Keyword(s):  
Sexual Behavior ◽  
Serum Testosterone ◽  
Juvenile Rats ◽  
Testosterone Levels ◽  
Tnf Α

scholarly journals SIGNS OF DIASTOLIC DYSFUNCTION ARE GRADED BY SERUM TESTOSTERONE LEVELS IN AGING C57BL/6 MALE MICE

2021 ◽  
pp. 111523
Author(s):  
Shubham Banga ◽  
Stefan Heinze-Milne ◽  
Judith Godin ◽  
Susan E. Howlett
Keyword(s):  
Diastolic Dysfunction ◽  
Serum Testosterone ◽  
Male Mice ◽  
Testosterone Levels

Effect of Traditional Herbal Medicine, Shakuyaku-Kanzo-To on Total and Free Serum Testosterone Levels

1989 ◽  
Vol 17 (01n02) ◽  
pp. 35-44 ◽  
Author(s):  
Toru Takeuchi ◽  
Osamu Nishii ◽  
Takashi Okamura ◽  
Tsutomu Yaginuma
Keyword(s):  
Herbal Medicine ◽  
Direct Action ◽  
Serum Testosterone ◽  
Total Serum ◽  
Aromatase Activity ◽  
Dependent Manner ◽  
Traditional Herbal Medicine ◽  
Testosterone Levels ◽  
Dose Dependent ◽  
Free Serum

The effect of the traditional herbal medicine, Shakuyaku-Kanzo-To (SK), which contains Shakuyaku (S) and Kanzo (K) in equal amounts, on serum testosterone levels was investigated in androgen-sterilized rats. They were given orally SK [0, 22.5, 45, 90 and 180 mg/kg body weight (b.w.)] and S or K (0, 11.25, 22.5, 40 and 90 mg/kg b.w.) in 2 ml of water daily for 2 weeks. Dose-dependent decreases in free serum testosterone (T) levels were found in the administration of SK. Total serum T levels in the administration of SK and S decreased in a dose-dependent manner. K decreased totla serum T levels slightly in 11.5 and 22.5 mg/kg doses but showed the dose-dependent increase in much higher doses, the extent of which was much less than that of the decrease in S. Serum estradiol/T (E2/T) ratios were significantly elevated in 45 to 180 mg/kg doses of SK, 90 mg/kg dose of S and 11.25 to 90 mg/kg doses of K. Serum LH and FSH levels were not changes by SK, S and K. Oophorectomized rats were similarly given SK (0, 90 and 180 mg/kg b.w.) and S or K (the half doses of SK). There were no changes in serum T, LH and FSH levels in all given doses. Thus, one of the mechanisms for SK to lower serum T levels in the direct action on the ovary to stimulate the aromatase activity, resulting in decreasing the T secretion and this is the additive effects of S and K.

1625: Role of Estrogen Receptor β in the Regulation of Sexual Behavior in Male Mice

2004 ◽  
Vol 171 (4S) ◽  
pp. 429-429
Author(s):  
Masayoshi Nomura ◽  
Naohiro Fujimoto ◽  
Donald W. Pfaff ◽  
Sonoko Ogawa ◽  
Tetsuro Matsumoto
Keyword(s):  
Estrogen Receptor ◽  
Sexual Behavior ◽  
Estrogen Receptor Β ◽  
Male Mice

Zinc Status and Serum Testosterone Levels of Healthy Adults

Nutrition ◽  
1996 ◽  
Vol 12 (5) ◽  
pp. vi
Author(s):  
A Prasad
Keyword(s):  
Serum Testosterone ◽  
Healthy Adults ◽  
Zinc Status ◽  
Testosterone Levels

Why Do We Need New Markers for Male Hypogonadism and How Seminal Proteomics Might Solve the Problem?

2020 ◽  
Vol 27 (12) ◽  
pp. 1186-1191
Author(s):  
Giuseppe Grande ◽  
Domenico Milardi ◽  
Silvia Baroni ◽  
Andrea Urbani ◽  
Alfredo Pontecorvi
Keyword(s):  
Serum Testosterone ◽  
Clinical Syndrome ◽  
Testosterone Replacement ◽  
Total Testosterone ◽  
Male Hypogonadism ◽  
Grey Zone ◽  
Testosterone Levels ◽  
Normal Number ◽  
Replacement Treatment

Male hypogonadism is “a clinical syndrome that results from failure of the testis to produce physiological concentrations of testosterone and/or a normal number of spermatozoa due to pathology at one or more levels of the hypothalamic– pituitary–testicular axis”. The diagnostic protocol of male hypogonadism includes accurate medical history, physical exam, as well as hormone assays and instrumental evaluation. Basal hormonal evaluation of serum testosterone, LH, and FSH is important in the evaluation of diseases of the hypothalamus-pituitary-testis axis. Total testosterone levels < 8 nmol/l profoundly suggest the diagnosis of hypogonadism. An inadequate androgen status is moreover possible if the total testosterone levels are 8-12 nmol/L. In this “grey zone” the diagnosis of hypogonadism is debated and the appropriateness for treating these patients with testosterone should be fostered by symptoms, although often non-specific. Up to now, no markers of androgen tissue action can be used in clinical practice. The identification of markers of androgens action might be useful in supporting diagnosis, Testosterone Replacement Treatment (TRT) and clinical follow-up. The aim of this review is to analyze the main findings of recent studies in the field of discovering putative diagnostic markers of male hypogonadism in seminal plasma by proteomic techniques. The identified proteins might represent a “molecular androtest” useful as a seminal fingerprint of male hypogonadism, for the diagnosis of patients with moderate grades of testosterone reduction and in the follow-up of testosterone replacement treatment.

scholarly journals Effects of pomegranate juice on the sexual behavior, fertility and protective activity against aluminum exposure in male mice

2020 ◽  
Vol 32 (6) ◽  
pp. 2688-2695
Author(s):  
Mohsen Ghaleb Al-Mutary ◽  
Gasem Mohammad Abu-Taweel
Keyword(s):  
Sexual Behavior ◽  
Pomegranate Juice ◽  
Protective Activity ◽  
Male Mice ◽  
Aluminum Exposure

scholarly journals Testosterone in Female Depression: A Meta-Analysis and Mendelian Randomization Study

Biomolecules ◽  
2021 ◽  
Vol 11 (3) ◽  
pp. 409
Author(s):  
Dhruba Tara Maharjan ◽  
Ali Alamdar Shah Syed ◽  
Guan Ning Lin ◽  
Weihai Ying
Keyword(s):  
Mendelian Randomization ◽  
Meta Analysis ◽  
Menopausal Status ◽  
Serum Testosterone ◽  
Serum Levels ◽  
Testosterone Levels ◽  
Mendelian Randomization Analysis ◽  
The Difference ◽  
Diagnostic Capabilities ◽  
Randomization Analysis

Testosterone’s role in female depression is not well understood, with studies reporting conflicting results. Here, we use meta-analytical and Mendelian randomization techniques to determine whether serum testosterone levels differ between depressed and healthy women and whether such a relationship is casual. Our meta-analysis shows a significant association between absolute serum testosterone levels and female depression, which remains true for the premenopausal group while achieving borderline significance in the postmenopausal group. The results from our Mendelian randomization analysis failed to show any causal relationship between testosterone and depression. Our results show that women with depression do indeed display significantly different serum levels of testosterone. However, the directions of the effect of this relationship are conflicting and may be due to menopausal status. Since our Mendelian randomization analysis was insignificant, the difference in testosterone levels between healthy and depressed women is most likely a manifestation of the disease itself. Further studies could be carried out to leverage this newfound insight into better diagnostic capabilities culminating in early intervention in female depression.

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