scholarly journals Rhododendron groenlandicum(Labrador tea), an antidiabetic plant from the traditional pharmacopoeia of the Canadian Eastern James Bay Cree, improves renal integrity in the diet-induced obese mouse model

2016 ◽  
Vol 54 (10) ◽  
pp. 1998-2006 ◽  
Author(s):  
Shilin Li ◽  
Antoine Brault ◽  
Mayra Sanchez Villavicencio ◽  
Pierre S. Haddad
Planta Medica ◽  
2011 ◽  
Vol 77 (05) ◽  
Author(s):  
M Ouchfoun ◽  
A Brault ◽  
D Vallerand ◽  
L Musallam ◽  
JT Arnason ◽  
...  

2015 ◽  
Vol 2015 ◽  
pp. 1-7 ◽  
Author(s):  
Michel Rapinski ◽  
Lina Musallam ◽  
John Thor Arnason ◽  
Pierre Haddad ◽  
Alain Cuerrier

The traditional medicinal plant, Labrador tea (Rhododendron groenlandicum(Oeder) Kron & Judd; Ericaceae), present in the pharmacopoeia of the Cree of Eeyou Istchee, has shown glitazone-like activity in the 3T3-L1 adipogenesis bioassay. This activity has been attributed to phenolic compounds, which have been shown to vary in this plant as a function of insolation parameters. The goal of this study was to determine if these changes in phenolic content were pharmacologically significant. Leaves were harvested in 2006 throughout the James Bay region of Northern Quebec and ethanol extracts were testedin vitrousing the 3T3-L1 murine cell line adipogenesis bioassay. This traditional medicinal plant was found active in the assay. However, there was no detectable spatial pattern in the accumulation of intracellular triglycerides, suggesting that such patterns previously observed in the phenolic profile of Labrador tea were not pharmacologically significant. Nonetheless, a reduction in the adipogenic activity was observed and associated with higher concentrations of quercetin for which selected environmental variables did not appropriately explain its variation.


Planta Medica ◽  
2011 ◽  
Vol 77 (12) ◽  
Author(s):  
HM Eid ◽  
M Ouchfoun ◽  
A Brault ◽  
D Vallerand ◽  
L Mussalam ◽  
...  

Diabetes ◽  
2020 ◽  
Vol 69 (Supplement 1) ◽  
pp. 1875-P ◽  
Author(s):  
EMI ISHIDA ◽  
XIAO LEI ◽  
EIJIRO YAMADA ◽  
SHUICHI OKADA ◽  
MASANOBU YAMADA

Diabetes ◽  
1993 ◽  
Vol 42 (12) ◽  
pp. 1731-1736 ◽  
Author(s):  
S. Andrikopoulos ◽  
G. Rosella ◽  
E. Gaskin ◽  
A. Thorburn ◽  
S. Kaczmarczyk ◽  
...  

2014 ◽  
Vol 24 (6) ◽  
pp. 608-614 ◽  
Author(s):  
Olivia Drescher ◽  
Eric Dewailly ◽  
Caroline Diorio ◽  
Nathalie Ouellet ◽  
Elhadji Anassour Laouan Sidi ◽  
...  

Amino Acids ◽  
2018 ◽  
Vol 51 (2) ◽  
pp. 245-254 ◽  
Author(s):  
Kyoung Soo Kim ◽  
Min Ju Jang ◽  
Sungsoon Fang ◽  
Seul Gi Yoon ◽  
Il Yong Kim ◽  
...  

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