Crescentic glomerulonephritis with antimyeloperoxidase antibodies developing during the course of IgA nephropathy in a patient with rheumatoid arthritis

2001 ◽  
Vol 11 (1) ◽  
pp. 76-79 ◽  
Author(s):  
M. Uchiyama ◽  
T. Akahoshi ◽  
T. Matsui ◽  
H. Watabe ◽  
K. Koredo ◽  
...  
Keyword(s):  
Rheumatoid Arthritis ◽  
Iga Nephropathy ◽  
Crescentic Glomerulonephritis

scholarly journals Amnesia in a Patient with Rheumatoid Arthritis: A Case of Granulomatosis with Polyangiitis

2020 ◽  
Vol 2020 ◽  
pp. 1-5
Author(s):  
Pablo Weilg ◽  
Giancarlo Diaz-Zamora ◽  
Larry Young
Keyword(s):  
Rheumatoid Arthritis ◽  
Crescentic Glomerulonephritis ◽  
Granulomatosis With Polyangiitis ◽  
Diffuse Alveolar Damage ◽  
Oral Prednisone ◽  
Small Region ◽  
Pulse Therapy ◽  
Steroid Pulse ◽  
Acute Infarction ◽  
History Of

A 56-year-old male with a history of seropositive rheumatoid arthritis complained of polyarthritis and forgetfulness. The initial CT scan of the head without contrast was negative for acute pathologies. However, as he continued to decline despite being on oral prednisone, an MRI of the head was ordered and revealed a subtle small region of acute infarction in the left mammillary body. He was diagnosed with granulomatosis with polyangiitis in light of his positive C-ANCA antibodies, PR3 antibody, and a kidney biopsy, which showed focal necrotizing pauci-immune crescentic glomerulonephritis. Despite undergoing steroid pulse therapy, the patient developed diffuse alveolar damage which finally responded to rituximab infusion.

scholarly journals Pauchi-immune Crescentic Glomerulonephritis Associated with Rheumatoid Arthritis

2009 ◽  
Vol 98 (11) ◽  
pp. 2879-2881
Author(s):  
Risshi Kudo ◽  
Seiji Hashimoto ◽  
Hiroaki Sasaki ◽  
Tasuku Nakagaki ◽  
Tomochika Maoka ◽  
...  
Keyword(s):  
Rheumatoid Arthritis ◽  
Crescentic Glomerulonephritis

scholarly journals Late-onset rheumatoid arthritis in a patient with successfully treated IgA nephropathy

2017 ◽  
Vol 89 (8) ◽  
pp. 77-79
Author(s):  
N V Chebotareva ◽  
I N Bobkova ◽  
S V Gulyaev
Keyword(s):  
Rheumatoid Arthritis ◽  
Renal Function ◽  
Iga Nephropathy ◽  
Clinical Case ◽  
Late Onset ◽  
Systemic Diseases ◽  
Radiological Patterns ◽  
The Common ◽  
Reduced Renal Function

The paper describes a rare clinical case of rheumatoid arthritis (RA) that developed in a patient 9 years after diagnosing IgA nephropathy. Kidney disease was characterized by a stable course with moderate urinary syndrome, hypertension, and reduced renal function. Immunosuppressive therapy using glucocorticosteroids and then mycophenolic acid led to remission of nephritis and recovery of renal function. However, the absence of nephritis activity and discontinuation of immunosuppressants was responsible for articular syndrome. The diagnosis of RA is based on its characteristic radiological patterns and immunological characteristics after ruling out a number of systemic diseases and infections. The common pathogenetic components of IgA nephropathy and RA, including the role of rheumatoid factor IgA, are discussed.

scholarly journals Rheumatoid Arthritis Associated with Renal Amyloidosis and Crescentic Glomerulonephritis.

1998 ◽  
Vol 37 (1) ◽  
pp. 94-97 ◽  
Author(s):  
Hideyuki MURAKAMI ◽  
Nobuyuki URA ◽  
Kazuhiko NAGAO ◽  
Kazufumi TSUCHIHASHI ◽  
Tomoaki NAKATA ◽  
...  
Keyword(s):  
Rheumatoid Arthritis ◽  
Crescentic Glomerulonephritis ◽  
Renal Amyloidosis

scholarly journals The Association of TNF-Alpha Inhibitors and Development of IgA Nephropathy in Patients with Rheumatoid Arthritis and Diabetes

2020 ◽  
Vol 2020 ◽  
pp. 1-8 ◽  
Author(s):  
Vedran Premužić ◽  
Ivan Padjen ◽  
Mislav Cerovec ◽  
Marijana Ćorić ◽  
Bojan Jelaković ◽  
...  
Keyword(s):  
Rheumatoid Arthritis ◽  
Diabetes Mellitus ◽  
Iga Nephropathy ◽  
Tnf Alpha ◽  
Prior History ◽  
Macroscopic Hematuria ◽  
The Third ◽  
Stage Renal Disease ◽  
End Stage ◽  
Alpha Therapy

IgA nephropathy (IgAN) is a rather uncommon complication of TNF-alpha inhibition with a range of findings such as asymptomatic microscopic/macroscopic hematuria or different degrees of proteinuria and could progress to end-stage renal disease. We are reporting three patients with longstanding rheumatoid arthritis (RA), which developed IgAN while receiving TNF-alpha inhibitors. All off our three patients had RA, which lasted 2–4 years, and none of them had a prior history of chronic kidney disease. Two patients were treated with adalimumab while one patient was treated with golimumab. Discontinuation of anti-TNF-alpha therapy and initiation of immunosuppressive therapy led to improvement in serologic abnormalities and renal function in two patients, while the third patient’s 24-hour proteinuria was only partially reduced, which supports previous reports on TNF-alpha inhibitor induced autoimmunity. Two of our patients had previously been diagnosed with type 2 diabetes mellitus while the third patient developed diabetes years after the onset of IgAN. This is in line with the previously described association of IgAN and diabetes mellitus. To our best knowledge, this is the first report to analyze the development of IgAN as a potential consequence of anti-TNF-alpha therapy and its possible association with pretreatment or posttreatment diabetes.

Sign in / Sign up

Export Citation Format

Share Document