scholarly journals Correction of extensive mitral paravalvular leak with three occlusion devices via transapical access: a case report

2021 ◽  
Vol 29 ◽  
pp. 1-4
Author(s):  
Luiz São Thiago ◽  
Luis Luciano ◽  
Ana Rabelo ◽  
Willian Conceição ◽  
Leandro Waldrich ◽  
...  
Keyword(s):  
Heart Valves ◽  
Surgical Intervention ◽  
Transcatheter Closure ◽  
Paravalvular Leak ◽  
Prosthetic Heart Valves ◽  
Heart Valve Diseases ◽  
Surgical Risk ◽  
High Surgical Risk ◽  
Valve Diseases ◽  
Transapical Access

Heart valve diseases account for a significant portion of hospitalizations due to cardiovascular diseases in Brazil. Prosthetic heart valves, which are often part of treatment, are susceptible to complications, such as paravalvular leak. Surgical intervention remains the treatment of choice for correcting this defect. However, transesophageal echocardiography-guided catheter correction has emerged as a less invasive alternative for paravalvular leak treatment in patients at high surgical risk. We report a case of extensive mitral paravalvular leak in a patient who had two previous cardiac surgeries and a high surgical risk, who underwent successful transcatheter closure with three prosthesis implantation by transapical access.

Dialdehyde pectin-crosslinked and hirudin-loaded decellularized porcine pericardium with improved matrix stability, enhanced anti-calcification and anticoagulant for bioprosthetic heart valves

2021 ◽  
Author(s):  
Mengyue Hu ◽  
Xu Peng ◽  
Yang Zhao ◽  
Xiaoshuang Yu ◽  
Can Cheng ◽  
...  
Keyword(s):  
Heart Valve ◽  
Heart Valves ◽  
Heart Valve Diseases ◽  
Bioprosthetic Heart Valves ◽  
Matrix Stability ◽  
Transcatheter Valve ◽  
Valve Diseases ◽  
Porcine Pericardium

To conveniently and effectively cure heart valve diseases or defects, combining with transcatheter valve technology, bioprosthetic heart valves (BHVs) originated from the decellularized porcine pericardium (D-PP) have been broadly used...

Heart Valve Diseases in the Elderly

2013 ◽  
pp. 240-260
Author(s):  
Yos Morsi ◽  
Zhang Li ◽  
Sheng Wang
Keyword(s):  
Valve Replacement ◽  
Heart Valve ◽  
Heart Valves ◽  
Heart Diseases ◽  
Heart Valve Replacement ◽  
Heart Valve Diseases ◽  
Full Account ◽  
Prosthetic Valves ◽  
Aortic Sclerosis ◽  
Valve Diseases

This chapter gives an overview of heart valve diseases, their diagnostics techniques, and current and future treatments with particular emphasis on the elder generation. It starts with a brief presentation of anatomy of the heart and its valves and the effect of aging on the function of the heart. Subsequently the projection of the global older population is given, and the most common and frequently occurring valvular heart diseases including aortic regurgitation, aortic stenosis, and aortic sclerosis are presented and discussed. Moreover, the current heart valve replacement techniques using mechanical or bio-prosthetic valves and the complications associated with the use of these artificial heart valves are presented and discussed. The chapter ends with a full account of the risk of mortality associated with the operation of heart valve replacement for older patients and the future directions for heart valve implementation using the tissue engineering concept.

An Unusual Localization of a Cardiac Pseudoaneurysm Complicated by Paravalvular Leak in a Patient with Prosthetic Heart Valves

2015 ◽  
Vol 33 (2) ◽  
pp. 330-332
Author(s):  
Mehmet A. Vatankulu ◽  
Osman Sönmez ◽  
Mehmet Akkaya ◽  
Cemalettin Aydin
Keyword(s):  
Heart Valves ◽  
Paravalvular Leak ◽  
Prosthetic Heart Valves

Transcatheter closure through transapical access for mitral paravalvular leak after previous trans-septal mitral operation

2016 ◽  
Vol 65 (5) ◽  
pp. 289-292 ◽  
Author(s):  
Takashi Murakami ◽  
Yasuo Suehiro ◽  
Shinsuke Nishimura ◽  
Kenichi Sugioka ◽  
Shinichi Iwata ◽  
...  
Keyword(s):  
Transcatheter Closure ◽  
Paravalvular Leak ◽  
Transapical Access

scholarly journals Is TEE a Game Changer in Aortic Prosthetic Paravalvular Leak?

2019 ◽  
Vol 03 (01) ◽  
pp. 42-44
Author(s):  
Devishree Das ◽  
Lakshya Sehgal ◽  
Ameya karanjkar ◽  
Sandeep Sharan ◽  
Poonam Malhotra Kapoor
Keyword(s):  
Prosthetic Valve ◽  
Heart Valves ◽  
Three Dimensional ◽  
Prosthetic Heart Valve ◽  
Paravalvular Leak ◽  
Prosthetic Heart Valves ◽  
Valve Prosthesis ◽  
Almost All ◽  
Axis View ◽  
Game Changer

AbstractValve prosthesis have played an important role in the management of patients with valvular heart disease. However, the prosthetic heart valves used are not without complications. Almost all prosthetic heart valves are obstructive compared with native valves and associated with physiological washing jets. Because of shielding and artifacts it is very difficult to assess the prosthetic valve with TTE. Multiple thrombi and aortomitral continuity detection is cumbersome by TTE. Multiple angulations and off axis view in TEE help not only to characterize the prosthetic heart valve but also gives a three-dimensional surgical view to aid in reaching a diagnosis.

scholarly journals Percutaneous Closure of Paravalvular Leak from a Rocking Mitral Valve in a 74-Year-Old Man at High Surgical Risk

2020 ◽  
Vol 47 (2) ◽  
pp. 160-162
Author(s):  
Frank E. Corrigan III ◽  
Jose Miguel Iturbe ◽  
Stamatios Lerakis ◽  
Norihiko Kamioka ◽  
Vasilis C. Babaliaros ◽  
...  
Keyword(s):  
Mitral Valve ◽  
Heart Valve ◽  
Multimodal Imaging ◽  
Cardiac Cycle ◽  
Surgical Repair ◽  
Prosthetic Heart Valve ◽  
Paravalvular Leak ◽  
Surgical Risk ◽  
High Surgical Risk ◽  
Poor Outcomes

Dehiscence of a prosthetic heart valve or excessive rocking during the cardiac cycle is thought to preclude percutaneous paravalvular leak closure. However, surgical repair of paravalvular leak is associated with recurrent dehiscence and poor outcomes. We present the case of a symptomatic 74-year-old man in whom we performed percutaneous anchoring, involving multiple plugs and multimodal imaging, to stabilize a rocking mitral valve and close a substantial paravalvular leak caused by dehiscence. To our knowledge, using this technique to correct both conditions is novel.

Transapical mitral valve-in-valve implantation in patients with degenerated bioprostheses and high surgical risk

2012 ◽  
Vol 60 (S 01) ◽  
Author(s):  
M Seiffert ◽  
L Conradi ◽  
S Baldus ◽  
J Schirmer ◽  
M Knap ◽  
...  
Keyword(s):  
Mitral Valve ◽  
Surgical Risk ◽  
High Surgical Risk ◽  
Valve In Valve ◽  
Valve Implantation

The Effect of Dipyridamole and RA 233 on Human Platelet Function in Vitro

1973 ◽  
Vol 29 (03) ◽  
pp. 694-700 ◽  
Author(s):  
Paul L. Rifkin ◽  
Marjorie B. Zucker
Keyword(s):  
Mechanism Of Action ◽  
Human Blood ◽  
Glass Bead ◽  
Heart Valves ◽  
Human Platelet ◽  
Drug Effects ◽  
Simple Relation ◽  
Prosthetic Heart Valves ◽  
Induced Aggregation

SummaryDipyridamole (Persantin) is reported to prolong platelet survival and inhibit embolism in patients with prosthetic heart valves, but its mechanism of action is unknown. Fifty jxM dipyridamole failed to reduce the high percentage of platelets retained when heparinized human blood was passed through a glass bead column, but prolonged the inhibition of retention caused by disturbing blood in vitro. Possibly the prostheses act like disturbance. Although RA 233 was as effective as dipyridamole in inhibiting the return of retention, it was less effective in preventing the uptake of adenosine into erythrocytes, and more active in inhibiting ADP-induced aggregation and release. Thus there is no simple relation between these drug effects.

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