scholarly journals Physical Inactivity is Related to Unheralded Myocardial Infarction More Than Uncomplicated Stable Angina

2018 ◽  
Vol 7 (3) ◽  
pp. 46-52
Author(s):  
Ali Vasheghani-Farahani ◽  
Somayeh Afshar ◽  
Maryam Salimnejad ◽  
Ebrahim Kasaian ◽  
Mohammad Ali Boroumand ◽  
...  
Keyword(s):  
Stable Angina ◽  
Physical Inactivity ◽  
Positive Family History ◽  
Chronic Stable Angina ◽  
Premature Coronary Artery Disease ◽  
C Reactive Protein ◽  
Protein Levels ◽  
Reactive Protein ◽  
History Of ◽  
Artery Disease

ABSTRACT Background: Ischemic heart disease can vary substantially in its clinical presentation. Some patients have acute myocardial infarction (MI) without any previous signs of myocardial ischemia, whereas other patients may have stable angina pectoris for years without periods of acute instability; this suggests the possibility of different risk influence in these 2 groups of patients. Methods: Cardiovascular risk factors were compared in 112 consecutive patients with unheralded MIs (81 men; 59.9 ± 11.6 years) and in 168 consecutive patients with chronic stable angina (108 men; 58.2 ± 10.5 years) with at least 60% occlusion in lumen diameter in 1 of the coronary vessels. Results: Logistic-regression analysis revealed that physical inactivity (odds ratio [OR]: 4.32, 95% CI = 2.07, 8.99; P < 0.0001), the values of high sensitive-C-reactive protein levels (OR: 1.05, 95% CI = 1.00, 1.11; P = 0.043), diabetes (OR: 2.88, 95% CI = 1.42, 5.83; P = 0.003), and positive family history of premature coronary artery disease (OR: 1.96, 95% CI: 1.04, 3.71; P = 0.038) were independent predictors of unheralded MI versus chronic stable angina. Conclusion: In our subjects, sedentary life, diabetes mellitus, positive family history of premature coronary artery disease, and higher high sensitive-C-reactive protein levels were important independent predictors for unheralded MI, which suggests that these factors are involved in thrombosis, plaque rupture, or both.

Multiple complex stenoses, high neutrophil count and C-reactive protein levels in patients with chronic stable angina

2004 ◽  
Vol 175 (1) ◽  
pp. 151-157 ◽  
Author(s):  
Pablo Avanzas ◽  
Ramón Arroyo-Espliguero ◽  
Juan Cosı́n-Sales ◽  
Juan Quiles ◽  
Emmanouil Zouridakis ◽  
...  
Keyword(s):  
Neutrophil Count ◽  
Stable Angina ◽  
Chronic Stable Angina ◽  
C Reactive Protein ◽  
Protein Levels ◽  
Reactive Protein

High-sensitivity C-reactive protein in the prediction of coronary events in patients with premature coronary artery disease

2002 ◽  
Vol 144 (3) ◽  
pp. 449-455 ◽  
Author(s):  
Walter S. Speidl ◽  
Senta Graf ◽  
Stefan Hornykewycz ◽  
Mariam Nikfardjam ◽  
Alexander Niessner ◽  
...  
Keyword(s):  
Coronary Artery Disease ◽  
Coronary Artery ◽  
High Sensitivity ◽  
Premature Coronary Artery Disease ◽  
C Reactive Protein ◽  
Reactive Protein ◽  
Coronary Events ◽  
Artery Disease

Complement C3 and C-reactive protein levels in patients with stable coronary artery disease

2005 ◽  
Vol 94 (11) ◽  
pp. 1048-1053 ◽  
Author(s):  
Ramzi Ajjan ◽  
Timothy Futers ◽  
Jane Brown ◽  
Charlotte Cymbalista ◽  
May Boothby ◽  
...  
Keyword(s):  
Coronary Artery Disease ◽  
Coronary Artery ◽  
Fasting Glucose ◽  
Stable Coronary Artery Disease ◽  
Complement C3 ◽  
C Reactive Protein ◽  
Protein Levels ◽  
Reactive Protein ◽  
The Metabolic Syndrome ◽  
Artery Disease

SummaryThe aim of this study was to determine whether complement C3 is an indicator of coronary artery disease (CAD). We measured plasma C3 and CRP levels in 278 patients undergoing coronary angiography for typical symptoms of CAD and 269 healthy age and sex matched controls. C3 levels were significantly higher in patients compared with controls (1.15 g/l and 0.92 g/l respectively; p<0.001). In the patient group, C3 levels correlated with BMI, fasting glucose, HbA1c, fibrinogen, CRP and HDL in both men and women. CRP levels were also higher in patients compared with controls (1.14 mg/l and 0.86 mg/l respectively; p=0.005) and correlated with markers of the metabolic syndrome. In a logistic regression model including C3, smoking, hypertension, cholesterol and diabetes, C3 was independently associated with CAD with an odds ratio of 3.20 for a 1 SD increase in C3 levels. In contrast, CRP was not independently associated with CAD in a similar regression analysis. In conclusion, both C3 and CRP plasma levels are elevated in patients with symptoms of CAD. However, C3 seems to be a better indicator of CAD than CRP in this study, suggesting that C3 could be an additional marker for risk stratification in atherosclerosis.

scholarly journals Elevated C-reactive protein levels and coronary microvascular dysfunction in patients with coronary artery disease

2005 ◽  
Vol 26 (20) ◽  
pp. 2099-2105 ◽  
Author(s):  
Fabrizio Tomai ◽  
Flavio Ribichini ◽  
Anna S. Ghini ◽  
Valeria Ferrero ◽  
Giuseppe Andò ◽  
...  
Keyword(s):  
Coronary Artery Disease ◽  
Coronary Artery ◽  
Microvascular Dysfunction ◽  
Coronary Microvascular Dysfunction ◽  
C Reactive Protein ◽  
Protein Levels ◽  
Reactive Protein ◽  
Artery Disease

scholarly journals Relationship between coronary artery disease and C-reactive protein levels in NSTEMI patients with renal dysfunction: a retrospective study

2014 ◽  
Vol 15 (1) ◽  
Author(s):  
Maria Udeanu ◽  
Giordano Guizzardi ◽  
Giuseppe Di Pasquale ◽  
Antonio Marchetti ◽  
Francesca Romani ◽  
...  
Keyword(s):  
Coronary Artery Disease ◽  
Retrospective Study ◽  
Coronary Artery ◽  
Renal Dysfunction ◽  
C Reactive Protein ◽  
Protein Levels ◽  
Reactive Protein ◽  
Artery Disease

Preprocedural C-reactive protein levels predict myocardial necrosis after successful coronary stenting in patients with stable angina

2006 ◽  
Vol 151 (6) ◽  
pp. 1265-1270 ◽  
Author(s):  
Alexander Goldberg ◽  
Luis Gruberg ◽  
Ariel Roguin ◽  
Sirouch Petcherski ◽  
Drora Rimer ◽  
...  
Keyword(s):  
Stable Angina ◽  
Myocardial Necrosis ◽  
Coronary Stenting ◽  
C Reactive Protein ◽  
Protein Levels ◽  
Reactive Protein

C-reactive protein levels are related to suicidality in euthymic patients with bipolar disorder

2016 ◽  
Vol 33 (S1) ◽  
pp. S337-S337
Author(s):  
M. Pantovic Stefanovic ◽  
B. Dunjic-Kostic ◽  
M. Lackovic ◽  
A. Damjanovic ◽  
A. Jovanovic ◽  
...  
Keyword(s):  
Suicide Attempts ◽  
Previous History ◽  
Control Group ◽  
Healthy Controls ◽  
C Reactive Protein ◽  
Course Of Illness ◽  
Protein Levels ◽  
Reactive Protein ◽  
History Of ◽  
Competing Interest

IntroductionImmune alterations are believed to be an important part in etiopathogenesis of affective disorders. However, it is not clear if the altered immune mediators are related to distinct disorders or particular psychopathology.AimsThe aim of our study was to explore the differences in C-reactive protein levels (CRP) between euthymic BD patients and healthy controls, as well as to explore the relationship between CRP and lifetime presented psychopathology within BD.MethodsThe study group consisted of 83 patients diagnosed with BD, compared to the healthy control group (n = 73) and matched according to age, gender, and body mass index (BMI). Lifetime psychopathology has been assessed according to predominant polarity as well as previous history of suicide attempts and psychotic episodes.ResultsThe CRP levels were significantly higher in BD patients when compared to healthy controls. After covarying for confounders, we observed that CRP levels, in euthymic BD patients, were related to number of previous suicide attempts, but not other indicators of lifetime psychopathology.ConclusionsBD patients per se, and particularly those with more suicide attempts, are more likely to present with proinflammatory state, even when in remission. Previous history of suicide attempts could bear specifically vulnerable endophenotype within BD. Systemic, longitudinal monitoring of the course of illness, and potential inflammatory mediators that underlie its systemic nature is warranted.Disclosure of interestThe authors have not supplied their declaration of competing interest.

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