Tear Film Evaluation in Contact Lens Wearers and Non Wearers

Background: Dry eye symptoms are more frequent in contact lens wearers than in non wearers. Dry eye is considered relatively common in contact lens wearers than non-wearers. However, there was no any report in our clinical setting that compared and addressed the issue related to dry eye and its symptom in contact lens wearers. The present study was conducted to compare pre-ocular tear lm in contact lens wearers (CLW) and contact lens non wearers (CLNW), and evaluate the relationship between clinical and subjective assessment of dry eye symptoms. Methods: It was a comparative study conducted among 131 subjects (262 eyes) attended in the contact lens clinic at BP Koirala Lions Center for the Ophthalmic Studies. Sixty five were daily soft contact lens wearers; sixty-six were non wearers. Tear function assessment included non- invasive tear break up time, invasive tear break up time, tear prism height and Schirmer II test. Subjective assessment of dry eye symptoms was carried out using McMonnies questionnaires. Results: Mean age of CLNW was 23.01± 5.53 and CLW was 23.6± 4.61. Female (89 subjects) visited more than male (42 subjects) in contact lens clinic. Mean symptom score in CLW was significantly higher than CLNW (p<0.001). But, distribution of symptomatology was not significantly different in both groups. Symptomatic subjects were elder (p<0.001) and female (p<0.05) in CLNW and only elder subjects in CLW. Tear function tests were significantly lower in symptomatic subjects in CLW and CLNW; Overall tear function test scores were also lower in CLW than CLNW. Tear function tests scores were insignificantly different in male and female. Coefficient of correlation was positive and weak for all tear function tests scores. Conclusions: Though, tear function tests scores were reduced in CLW than CLNW, dry eye symptomatology was almost similar. Subjective assessment of symptoms is as important as clinical tests. DOI: http://dx.doi.org/10.3126/joim.v34i2.9044 Journal of Institute of Medicine August, 2012; 34:2 14-20

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Tear film measurements in four different ethnic groups: Malay, Chinese, Indian and Nigerian

International Eye Research ◽

10.18240/ier.2021.02.02 ◽

2021 ◽

Vol 2 (2) ◽

pp. 69-73

Author(s):

Madhavendra Bhandari ◽

Keyword(s):

Ethnic Groups ◽

Tear Film ◽

Normal Subjects ◽

Blink Rate ◽

Non Invasive ◽

Significant Difference ◽

Surface Disorder ◽

Eye Symptoms ◽

Break Up ◽

Dry Eye Symptoms

AIM: To compare the non-invasive tear film break-up time (NIBUT), tear break up time (TBUT), basal tear secretion (BTS) and blink rate in four ethnic groups: Malay, Chinese, Indian and Nigerian. METHODS: Totally 120 healthy (61 males and 59 females) subjects (without dry eye symptoms and ocular surface disorder) with the age 20 to 39 years were recruited; 30 were Malays, 30 were Chinese, 31 were Indians and 29 were Nigerians. Based on McMonnies questionnaire and clinical examination, normal subjects were selected. NIBUT, TBUT, BTS were assessed in only one eye (right) of each subject and blink rate was also assessed. RESULTS: There was significant difference in the NIBUT, TBUT, BTS and blink rate among 4 different ethnic groups (P=0.018, 0.001, 0.011, and 0.004 respectively). No statistically significant difference of NIBUT, TBUT, BTS and blink rate was found between the genders among different ethnic groups. Indian had higher median for NIBUT (10±6s), TBUT (7±5s) and BTS (20±20 mm) than other races. Chinese had lower median for NIBUT (7.5±4s) and TBUT (4±2s) while Malay had for BTS (9.5±16 mm) among the groups. There was no significant correlation of blink rate with NIBUT (r=-0.119, P=0.195), TBUT (r=-0.086, P=0.352), and BTS (r=-0.123, P=0.180) respectively. CONCLUSION: The tear-film measurement values are variability in four ethnic groups.

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Observation of tear film break-up time in patients with evaporative dry eye symptoms using EvoTears® eye drops compared to eye drops containing lipids

http://isrctn.com/ ◽

10.1186/isrctn15512057 ◽

2020 ◽

Author(s):

Dorothea Gross

Keyword(s):

Dry Eye ◽

Tear Film ◽

Eye Drops ◽

Eye Symptoms ◽

Evaporative Dry Eye ◽

Break Up ◽

Dry Eye Symptoms

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IMPACT OF ORBICULARIS OCULI MUSCLE STRIP EXCISION DURING UPPER LID BLEPHAROPLASTY ON TEAR FILM BREAK UP TIME AND POSTOPERATIVE DRY EYE SYMPTOMS

Al-Azhar Medical Journal ◽

10.12816/0052816 ◽

2018 ◽

Vol 47 (3) ◽

pp. 539-550

Author(s):

Mostafa F Mohammed

Keyword(s):

Dry Eye ◽

Tear Film ◽

Muscle Strip ◽

Orbicularis Oculi Muscle ◽

Orbicularis Oculi ◽

Eye Symptoms ◽

Upper Lid ◽

Break Up ◽

Dry Eye Symptoms

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Comparable effects on tear film parameters after femtosecond laser-assisted and conventional cataract surgery

International Ophthalmology ◽

10.1007/s10792-020-01532-z ◽

2020 ◽

Vol 40 (11) ◽

pp. 3097-3104 ◽

Cited By ~ 1

Author(s):

Marc Schargus ◽

Svetlana Ivanova ◽

Gesa Stute ◽

H. Burkhard Dick ◽

Stephanie C. Joachim

Keyword(s):

Femtosecond Laser ◽

Cataract Surgery ◽

Dry Eye ◽

Surgical Techniques ◽

Tear Film ◽

Schirmer Test ◽

Fluorescein Staining ◽

Significant Difference ◽

Eye Symptoms ◽

Dry Eye Symptoms

Abstract Purpose Dry eye symptoms after conventional cataract surgery are a very common problem. Until now, only few data are available on objective tear film parameters in regard to femtosecond laser-assisted cataract surgery (LCS). Aim of this study was therefore to analyze and compare tear film parameter changes between LCS and conventional cataract surgery. Methods A consecutive group of 34 patients, scheduled for cataract surgery, were randomly selected for either LCS or conventional cataract surgery (17 patients/group). Tear film assessments including tear film osmolarity, Schirmer test, MMP-9 analysis via quantitative ELISA, corneal sensitivity, corneal fluorescein staining, and conjunctival fluorescein staining were sequentially evaluated pre- as well as 1 and 3 months postoperatively. Results Both groups showed no significant difference in baseline characteristics. All surgeries were performed without any complications. After 1 and 3 months, there was no statistically significant difference in regard to tear film osmolarity (1 month: p = 0.81, 3 months: p = 1.0), Schirmer test (1 month: p = 0.35, 3 month: p = 0.08), and MMP-9 concentration (1 month: p = 0.36, 3 month: p = 0.28) between the two groups. Conclusions Neither LCS nor conventional cataract surgery affected objective tear film parameters significantly during our 3-month postoperative observation period. Hence, both surgical techniques can be equally used to treat patients without prior dry eye symptoms.

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Photophobia and sensations of dryness in patients with migraine occur independent of baseline tear volume and improve following botulinum toxin A injections

British Journal of Ophthalmology ◽

10.1136/bjophthalmol-2018-312649 ◽

2018 ◽

Vol 103 (8) ◽

pp. 1024-1029 ◽

Cited By ~ 7

Author(s):

Ryan J Diel ◽

Jodi Hwang ◽

Zachary A Kroeger ◽

Roy C Levitt ◽

Constantine D Sarantopoulos ◽

...

Keyword(s):

Botulinum Toxin ◽

Chronic Migraine ◽

Dry Eye ◽

Botulinum Toxin A ◽

Demographic Data ◽

Tear Film ◽

Phenol Red ◽

Toxin A ◽

Eye Symptoms ◽

Dry Eye Symptoms

BackgroundTo evaluate the efficacy of botulinum toxin A (BoNT-A) in reducing photophobia and dry eye symptoms in individuals with chronic migraine. Additionally, we aimed to evaluate tear film volume as a potential contributor to symptoms in these patients.MethodsRetrospective review of 76 patients who received BoNT-A for chronic migraine between 23 August 2017 and 13 December 2017 at the Miami Veterans Affairs Medical Center Neurotoxin Clinic. Demographic data and all comorbidities were queried via chart review. Standardised validated surveys were administered to assess symptoms prior to and after BoNT-A injection. Preinjection tear volumes were obtained using the phenol red thread (PRT) test.ResultsPreinjection migraine, photophobia and dry eye symptom scores were all significantly correlated, p<0.05, and none were associated with preinjection PRT results. After BoNT-A, improvements in migraine, photophobia and dry eye symptoms were also significantly correlated, p<0.05 and similarly did not associate with preinjection PRT results. Photophobia scores significantly improved following BoNT-A, while dry eye symptoms significantly improved in those with severe symptoms at baseline (DEQ-5 score ≥12), p=0.027. In logistic regression analysis of all individuals with dry eye symptoms (DEQ-5 ≥6), individuals with more severe dry eye symptoms were more likely improve, OR 1.27, 95% CI 1.06 to 1.51, p<0.01.ConclusionsBoNT-A significantly improved photophobia in patients being treated for migraine and also improved dry eye symptoms in patients with severe symptoms at baseline, independent of baseline tear film volume. These improvements may be due to modulation of shared trigeminal neural pathways.

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