scholarly journals Cyto-histopathological study of Mediastinal lesions

2016 ◽  
Vol 6 (11) ◽  
pp. 928-931
Author(s):  
N Bhattarai
Keyword(s):  
Needle Aspiration ◽  
University Teaching ◽  
Histopathological Study ◽  
Anatomical Site ◽  
Institute Of Medicine ◽  
Female Ratio ◽  
Non Hodgkin Lymphoma ◽  
Mediastinal Masses ◽  
Needle Aspiration Cytology ◽  
Middle Compartment

Background: Broad ranges of non-neoplastic and neoplastic lesions are encountered in mediastinum depending on the patient’s age and anatomical site. This study was performed to review our institutional experience of mediastinal masses and to compare the results with various other studies.Materials and Methods: This was a retrospective study conducted on 112 patients with mediastinal masses who underwent fine needle aspiration cytology and/or biopsy from 14th April 2009 to 4th March 2014 in Department of Pathology, Institute of Medicine, Tribhuvan University Teaching Hospital.Results: Out of 112 cases, 70 cases (62.5%) were benign, 38 cases (33.92%) malignant and 4 cases (3.57%) were inconclusive. Mean age of presentation was 34.94 yrs with male to female ratio of 1.2:1. Ninety-nine cases (88.4%) were seen in anterior compartment, 12 cases (10.7%) in posterior compartment and 1case (0.9%) in middle compartment. Thymoma (26 cases) was the most common lesion followed by Non Hodgkin lymphoma (17 cases) and germ cell tumor (16 cases).Conclusion: Mediastinal lesions occur more commonly in males with higher frequency of benign lesions, among which thymoma is the predominant lesion.

scholarly journals Correlation of FNAC and histopathology in diagnosis of salivary gland lesions

2014 ◽  
Vol 4 (8) ◽  
pp. 654-657 ◽  
Author(s):  
S Koirala ◽  
G Sayami ◽  
AD Pant
Keyword(s):  
Salivary Gland ◽  
Preoperative Diagnosis ◽  
Needle Aspiration ◽  
University Teaching ◽  
Malignant Neoplasms ◽  
Histopathological Diagnosis ◽  
Institute Of Medicine ◽  
Needle Aspiration Cytology ◽  
Sensitivity Specificity ◽  
Diagnostic Pitfalls

Background: Value of fine needle aspiration cytology in preoperative diagnosis of salivary gland lumps has been established in various studies. This study aims to calculate sensitivity, specificity accuracy of FNAC, correlate FNAC findings with histopathology and find out reasons for common diagnostic pitfalls in FNAC.Materials and methods: This study was performed in 67 patients that presented with salivary gland lumps at Department of pathology, Tribhuvan University Teaching Hospital, Institute of medicine, Kathmandu, Nepal from January 2009 to June 2010. FNAC was performed and was correlated with histopathological diagnosis to judge the sensitivity, specificity and accuracy of FNAC.Results: Out of 36 cases there was cyto-histological correlation in 28 cases. Pleomorphic adenoma was the most frequent lesion in this study. Parotid gland was the most common site affected by salivary gland lesions. The sensitivity, specificity and accuracy for non-neoplastic lesions was 100%, 89.28%, 91.67%, for benign neoplasms was 100%, 86.95%, 91.67% and for malignant neoplasms was 57.14%, 100%, 83.33% respectively.Conclusion: FNAC is a useful tool in preoperative diagnosis of salivary gland lesions and can be crucial for the management of the patient. Aspiration and reporting of salivary gland lesions demands a competent pathologist who considers all the possible diagnostic pitfalls in mind.DOI: http://dx.doi.org/10.3126/jpn.v4i8.11593 Journal of Pathology of Nepal; Vol.4,No. 8 (2014) 654-657

scholarly journals Fine needle aspiration cytology of cystic lesions of head and neck

2018 ◽  
Vol 8 (2) ◽  
pp. 1360-1364 ◽  
Author(s):  
Narendra Bhattarai ◽  
Akanksha Kushwah
Keyword(s):  
Head And Neck ◽  
Cost Effective ◽  
Needle Aspiration ◽  
University Teaching ◽  
Epidermal Cyst ◽  
Anatomical Site ◽  
Tuberculous Lymphadenitis ◽  
Cystic Lesions ◽  
Institute Of Medicine ◽  
Common Diagnosis

Background: Many non-neoplastic and neoplastic lesions are encountered as cystic lesions of head and neck depending on the patient’s age and anatomical site. Value of FNAC in preoperative diagnosis of these lesions has been established in various study.Materials and Methods: The study was performed in 333 patients that presented as cystic lesions of head and neck at Department of Pathology, Tribhuvan University Teaching Hospital, Institute of Medicine, Kathmandu, Nepal from July 2013 to June 2014.RESULTS: Cystic lesions in head and neck accounted for 11.35% of all FNACs. The median age of the patients was 31 years and the majority of the patients were in the age group of 21-30 years with slight female predilection. Lateral neck was the most common site with lymph node (31.9%) the most common organ of involvement. Tuberculous lymphadenitis was the most common diagnosis with 21% of cases, followed by colloid goiter with cystic change and epidermal cyst. Pus was the most common aspiration finding. Sensitivity and specificity of FNAC in diagnosing malignancy was 83.3% and 100% respectivelyCONCLUSION: A significant number and wide variety of lesions present as cystic lesions of head and neck. FNAC is useful and cost effective tool to classify, diagnose and rule out malignancy in these cases.

scholarly journals Clinicopathological features of pilomatricoma cases: Analysis of 21 cases

2014 ◽  
Vol 4 (7) ◽  
pp. 530-533
Author(s):  
D Ghartimagar ◽  
A Ghosh ◽  
K Gautam ◽  
S Thapa ◽  
SR Shrestha ◽  
...  
Keyword(s):  
Hair Follicle ◽  
Needle Aspiration ◽  
Common Finding ◽  
Clinical Impression ◽  
Aspiration Cytology ◽  
Female Ratio ◽  
Male Female Ratio ◽  
Needle Aspiration Cytology ◽  
Age Range ◽  
Slow Growing

Background: Pilomatricoma is a slow-growing, asymptomatic tumour originating from outer sheath cells of hair follicle. In this study, we describe the clinical presentation and histopathological features of pilomatricoma. Materials and Methods: This was a hospital based retrospective study carried out in all patients who were diagnosed as pilomatricoma over a period of January 2001 to December 2013. The study was done in department of pathology, Manipal Teaching Hospital, Nepal. Results: A total of 21 cases of pilomatricoma were reported with age range of 9-53 years (mean age 23.7) and male female ratio of 1:1.1. The most common site of occurrence was neck and preauricular region. The size of the tumour ranged from 0.3 to 4.7cm with a mean of 1.2cm. Multiple occurrences were seen in 3 patients and ossifying pilomarticoma was seen in 4 cases. Conclusion: Pilomatricoma is a benign skin neoplasm of hair follicle matrix cells. Calcification is a common finding while dystrophic ossification also can occur in the tumour. Histopathology gives the definite diagnosis as fine needle aspiration cytology and clinical impression may be misleading. DOI: http://dx.doi.org/10.3126/jpn.v4i7.10293 Journal of Pathology of Nepal (2014) Vol. 4, 530-533

ROLE OF FINE NEEDLE ASPIRATION CYTOLOGY (FNAC) IN BONE TUMORS AND TUMOR LIKE LESIONS

2021 ◽  
pp. 69-70
Author(s):  
Ragini Kumari ◽  
Vikash M. Harinandan ◽  
Kunal Shankar ◽  
Ajit Kumar Chaudhary ◽  
Debarshi Jana
Keyword(s):  
Fine Needle Aspiration ◽  
Bone Tumors ◽  
Needle Aspiration ◽  
Bone Lesions ◽  
Diagnostic Modality ◽  
Predictive Values ◽  
Female Ratio ◽  
Fine Needle ◽  
Needle Aspiration Cytology

Background: FNAC is considered an important procedure in the diagnosis of bone tumors because of its high accuracy. In our study FNA was performed in patients to study the role of FNAC in the diagnosis of bone tumors and to evaluate its usefulness as a diagnostic modality. Methods: Fine needle aspiration was performed on 54 patients whose age ranged between 5 – 75 years with a male to female ratio 1.84 :1 presented with various bone lesions. The bone lesions included 42 (78%) primary lesions, 5 (9.3%) metastatic deposits and 7 (12. 7%) malignancy of related structures involving the bone. Results: 47 biopsy specimens were available for cytohistological correlation and cytological ndings of 45 cases correlated with histopathology. The overall diagnostic accuracy was 95.92%, with 100% sensitivity and specicity. The predictive values of positive as well as negative test were 100%. Conclusions:Thus FNAwas found to be a safe and an extremely useful, rapid method in the preliminary diagnosis of bone lesions.

scholarly journals Primary ovarian non-Hodgkin lymphoma: Diagnosis of two cases on fine needle aspiration cytology

CytoJournal ◽  
2016 ◽  
Vol 13 ◽  
pp. 2 ◽  
Author(s):  
Rajni Yadav ◽  
Partheeban Balasundaram ◽  
Asit R. Mridha ◽  
Venkateswaran K. Iyer ◽  
Sandeep R. Mathur
Keyword(s):  
Hodgkin Lymphoma ◽  
Fine Needle Aspiration ◽  
Fine Needle Aspiration Cytology ◽  
Systemic Disease ◽  
B Cell Lymphoma ◽  
Needle Aspiration ◽  
Aspiration Cytology ◽  
Fine Needle ◽  
Non Hodgkin Lymphoma ◽  
Needle Aspiration Cytology

Lymphoma of the female genital tract is a rare condition. Involvement of the ovary by non- Hodgkin lymphoma (NHL) is usually secondary to systemic disease and primary ovarian lymphomas are unusual. In most cases, the diagnosis is not suspected initially and is confirmed only after detailed histopathological evaluation. We describe two cases of primary ovarian NHL which were diagnosed on fine needle aspiration cytology (FNAC). One of the patients was a 40 years old female who presented with abdominal distension and lump. She was found to have bilateral adnexal masses on ultrasound and computed tomography (CT) scan. A USG guided fine needle aspiration of the ovarian masses was performed, following which a diagnosis of primary ovarian diffuse large B-cell lymphoma was established. The second patient was a 14 years old female who presented with pelvic lump, which was lobulated and mildly enhancing on contrast enhanced CT. A diagnosis of high grade NHL of ovaries was made on cytology. Subsequently, the lymphoma was characterized as Burkitt's on histopathological examination. Both the patients were started on R-CHOP chemotherapy regimen. FNAC serves as an extremely useful minimally invasive procedure for the diagnosis of ovarian lymphomas and early institution of appropriate chemotherapeutic regimens.

scholarly journals Role of fine-needle aspiration cytology in evaluating mediastinal masses

Lung India ◽  
2009 ◽  
Vol 26 (4) ◽  
pp. 114 ◽  
Author(s):  
I Masood ◽  
SK Singh ◽  
Z Jairajpuri ◽  
DK Pandey ◽  
Zuber Ahmad
Keyword(s):  
Fine Needle Aspiration ◽  
Fine Needle Aspiration Cytology ◽  
Needle Aspiration ◽  
Aspiration Cytology ◽  
Fine Needle ◽  
Mediastinal Masses ◽  
Needle Aspiration Cytology

scholarly journals Fine needle aspiration cytology findings of mucinous carcinoma of breast: a study of eight cases with histological correlation

2012 ◽  
Vol 2 (4) ◽  
pp. 285-288
Author(s):  
RC Adhikari ◽  
A Jha
Keyword(s):  
Invasive Ductal Carcinoma ◽  
Fine Needle Aspiration ◽  
Fine Needle Aspiration Cytology ◽  
Ductal Carcinoma ◽  
Mucinous Carcinoma ◽  
Needle Aspiration ◽  
University Teaching ◽  
Aspiration Cytology ◽  
Fine Needle ◽  
Needle Aspiration Cytology

Background: Pure mucinous carcinoma is a rare histologic type of mammary neoplasm and may exist as mixed mucinous-ductal carcinoma. This study aims to describe fine needle aspiration cytology features of mucinous carcinoma of breast diagnosed in Tribhuvan University Teaching Hospital, Nepal over the period of 2 years and to correlate with histological findings.Materials and Methods: There were a total of 8 cases of mucinous carcinoma of breast, diagnosed on fine needle aspiration cytology in TUTH during the period from April 2010 to March 2012. The patient’s age, laterality of involvement, fine needle aspiration cytology features, gross and histological findings, type of surgery performed and tumor size were evaluated. Fine needle aspiration cytology smears were evaluated for cellularity, amount of mucin, chicken-wire vasculature and nuclear atypia.Results: Fine needle aspiration cytology provided a pre-operative diagnosis of mucinous carcinoma in 5 cases and mixed mucinous carcinoma-invasive ductal carcinoma in 3 cases. Histological examination showed pure mucinous carcinoma in 3 cases, mixed mucinous carcinoma-invasive ductal carcinoma in 4 cases and mixed cribriform carcinoma and ductal carcinoma in 1 case.Conclusion: Mucinous carcinoma may appear clinically and radiologically benign and fine needle aspiration cytology plays important role in the correct pre-operative diagnosis. Significant nuclear pleomorphism and necrosis, in addition to extracellular mucin suggests mixed mucinous carcinomainvasive ductal carcinoma.Journal of Pathology of Nepal (2012) Vol. 2, 285-288DOI: http://dx.doi.org/10.3126/jpn.v2i4.6879

scholarly journals Lymph node infarction and lymphoma

2014 ◽  
Vol 4 (7) ◽  
pp. 591-593
Author(s):  
R Pai ◽  
D Ghartimagar ◽  
U Khadilkar ◽  
M Pai ◽  
A Kini
Keyword(s):  
Hodgkin Lymphoma ◽  
Inflammatory Process ◽  
Needle Aspiration ◽  
Nuclear Chromatin ◽  
Aspiration Cytology ◽  
Incision And Drainage ◽  
Fine Needle ◽  
Parotid Region ◽  
Non Hodgkin Lymphoma ◽  
Needle Aspiration Cytology

Non Hodgkin lymphoma with infarction at initial presentation is rare and can be confused with an acute inflammatory process. A 47 year-old-man presented with complaint of swelling in the left parotid region for 2 weeks which increased in size with severe, continuous and throbbing pain in the last 2-3 days. A clinical diagnosis of parotid abscess was made. Incision and drainage did not yield any pus. Fine needle aspiration cytology showed a highly cellular tumor comprising of somewhat uniform round cells with granular nuclear chromatin. Ghost outline of cytoplasm was noted. A diagnosis of infarcted neoplasm of the parotid gland, probably acinic cell carcinoma was suggested. Histopathologically, it was reported as non-Hodgkin lymphoma with infarction which was confirmed by immunohistochemistry. DOI: http://dx.doi.org/10.3126/jpn.v4i7.10319 Journal of Pathology of Nepal (2014) Vol. 4, 591-593 

scholarly journals Comparing of Fine Needle Aspiration Cytology (FNAC) and Tru-cut biopsy for the Diagnosis of Breast Pathology

2021 ◽  
Vol 7 (1) ◽  
pp. 33-37
Author(s):  
Bidyut Chandra Debnath ◽  
Abanti Ghosh ◽  
Abul Kalam Chowdhury ◽  
Rana Jahangir ◽  
Ferdous Alam ◽  
...  
Keyword(s):  
Fine Needle Aspiration ◽  
Fine Needle Aspiration Cytology ◽  
Central Zone ◽  
Needle Aspiration ◽  
Breast Pathology ◽  
Aspiration Cytology ◽  
Female Ratio ◽  
Fine Needle ◽  
Significant Difference ◽  
Needle Aspiration Cytology

Background: Diagnosis of breast pathology is very important for the management of the patients. Objective: The purpose of the present study was to compare the fine needle aspiration cytology (FNAC) and trucut biopsy for the diagnosis of breast pathology. Methodology: This analytical cross-sectional study was conducted in the Department of Surgery at Bangabandhu Shiekh Mujib Medical University, Dhaka, Bangladesh from 1 April to 31 October 2020 for a period of six months. All the women who were attended at the OPD of the Department of Surgery with the different complaints of breast at any age were selected as study population. The different disease profiles were recorded in the data sheet. Result: A total number of 200 patients were recruited for this study. The mean age with standard deviation was 33.85±7.969 years. The male and female ratio was 1:19. Breast pathology was found in equal in left and right side which was 100(50.0%) cases in each. The central zone was the most common area which was 90(45.0%) cases. Most of the breast pathology was firm which was 170(85.0%) cases. The comparison of FNAC and tru-cut biopsy was done. Fibroadenoma was found in 50(100.0%) cases in FNAC; but in tru-cut biopsy 10(20.0%) case was fibroadenoma; invasive ductal carcinoma was in 30(60.0%) cases and the rest of 10(20.0%) case was Phylloides tumor. In FNAC 1 case was diagnosed as gynaecomatia which was diagnosed as intradermal papilloma in tru-cut biopsy. The difference between the FNAC and tru-cut biopsy for the detection of different pathology of breast was statistically significant (p=0.000). Conclusion: In conclusion there is a significant difference between FNAC and tru-cut biopsy for the detection of breast pathology. Journal of National Institute of Neurosciences Bangladesh, January 2021, Vol. 7, No. 1, pp. 33-37

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