scholarly journals Extra nodal Rosai Dorfman disease of nasal septal mucosa without lymphadenopathy

2016 ◽  
Vol 6 (11) ◽  
pp. 968-970
Author(s):  
P Raje ◽  
P Vyas
Keyword(s):  
Lymph Nodes ◽  
Head And Neck ◽  
Nasal Septum ◽  
Sinus Histiocytosis ◽  
Extranodal Involvement ◽  
Massive Lymphadenopathy ◽  
Rosai Dorfman Disease ◽  
Systemic Symptoms

Rosai–Dorman disease, also known as sinus histiocytosis with massive lymphadenopathy, typically presents as massive enlargement of lymph nodes accompanied by systemic symptoms. Extranodal involvement is also known usually in head and neck regions. Rarely the disease presents at extranodal sites only without involvement of lymph nodes.We present a case of 58 years-old female who presented with mass in nasal septum without involvement of lymph nodes. The mass was removed surgically and diagnosis was made on histological grounds with classical indings of histiocytic proliferation and emperipolesis.

Review of Sinus Histiocytosis with Massive Lymphadenopathy (Rosai-Dorfman Disease) of Head and Neck

1999 ◽  
Vol 108 (11) ◽  
pp. 1095-1104 ◽  
Author(s):  
Antonino Carbone ◽  
Kenneth O. Devaney ◽  
Alberto Passannante ◽  
Alessandra Rinaldo ◽  
Annunziata Gloghini ◽  
...  
Keyword(s):  
Head And Neck ◽  
Sinus Histiocytosis ◽  
Massive Lymphadenopathy ◽  
Rosai Dorfman Disease

scholarly journals Rosai-Dorfman disease with cutaneous plaques and autoimmune haemolytic anemia

2019 ◽  
Vol 12 (11) ◽  
pp. e231927
Author(s):  
Sweta Subhadarshani ◽  
Tarun Kumar ◽  
Sudheer Arava ◽  
Somesh Gupta
Keyword(s):  
Lymph Nodes ◽  
Haemolytic Anaemia ◽  
Disease Process ◽  
Autoimmune Haemolytic Anaemia ◽  
Diagnostic Challenge ◽  
Extranodal Involvement ◽  
Massive Lymphadenopathy ◽  
Rosai Dorfman Disease ◽  
Oral Corticosteroids ◽  
Haemolytic Anemia

Sinus histiocytosis with massive lymphadenopathy (Rosai-Dorfman disease) is a non-Langerhan cell histiocytosis which primarily involves lymph nodes. Extranodal involvement in the form of cutaneous plaques can occur and can pose a diagnostic challenge because of pleomorphic presentation and histopathological mimics. Rarely, systemic autoimmune involvement may complicate the disease process. We present a 28-year-old woman with slowly evolving scaly erythematous cutaneous plaques and fluctuating lymphadenopathy, associated with autoimmune haemolytic anaemia. The patient responded favourably to oral corticosteroids and acitretin with significant flattening of cutaneous plaques, reduction in size of neck nodes and improvement of anaemia.

Sinus Histiocytosis with Massive Lymphadenopathy (Rosai-Dorfman Disease): Imaging Manifestations in the Head and Neck

2008 ◽  
Vol 191 (6) ◽  
pp. W299-W306 ◽  
Author(s):  
Donald V. La Barge ◽  
Karen L. Salzman ◽  
H. Ric Harnsberger ◽  
Lawrence E. Ginsberg ◽  
Bronwyn E. Hamilton ◽  
...  
Keyword(s):  
Head And Neck ◽  
Sinus Histiocytosis ◽  
Massive Lymphadenopathy ◽  
Rosai Dorfman Disease

Rosai-Dorfman Disease Involving the Nasal Septum

1995 ◽  
Vol 74 (12) ◽  
pp. 831-839 ◽  
Author(s):  
Adnan Özünlü ◽  
Ahmet Dündar ◽  
Altan Yildirim ◽  
F. Rüstü Yildiz
Keyword(s):  
Nasal Septum ◽  
Sinus Histiocytosis ◽  
Nodal Involvement ◽  
Massive Lymphadenopathy ◽  
Rosai Dorfman Disease

Rosai-Dorfman disease, or sinus histiocytosis with massive lymphadenopathy (SHML), is a benign, self-limited pseudolymphomatous entity with characteristic histologic features. The disease may be atypically present in the absence of detectable nodal involvement. This is a case of nasal septum involvement of Rosai-Dorfman disease without clinically apparent lymphadenopathy.

Extranodal sinus histiocytosis with massive lymphadenopathy (Rosai-Dorfman disease) of the head and neck

1993 ◽  
Vol 24 (5) ◽  
pp. 483-492 ◽  
Author(s):  
Bruce M. Wenig ◽  
Susan L. Abbondanzo ◽  
Esther L. Childers ◽  
Silloo B. Kapadia ◽  
Dennis R. Heffner
Keyword(s):  
Head And Neck ◽  
Sinus Histiocytosis ◽  
Massive Lymphadenopathy ◽  
Rosai Dorfman Disease

Primary Pancreatic Sinus Histiocytosis With Massive Lymphadenopathy (Rosai-Dorfman Disease): An Unusual Extranodal Manifestation Clinically Simulating Malignancy

2010 ◽  
Vol 134 (2) ◽  
pp. 276-278 ◽  
Author(s):  
Mark Podberezin ◽  
Ronald Angeles ◽  
Grace Guzman ◽  
David Peace ◽  
Sujata Gaitonde
Keyword(s):  
Adipose Tissue ◽  
Lymph Node ◽  
Unusual Case ◽  
Sinus Histiocytosis ◽  
Gastrointestinal System ◽  
Rare Entity ◽  
Massive Lymphadenopathy ◽  
Rosai Dorfman Disease

Abstract Sinus histiocytosis with massive lymphadenopathy (SHML), also called Rosai-Dorfman disease, is a rare entity. Its etiology and pathogenesis are still essentially unclear. The histologic hallmark of this disease is proliferation of distinctive histiocytes within lymph node sinuses and in extranodal sites. Approximately 23% of patients with SHML, documented in the SHML Registry, presented with disease primarily in extranodal sites, and very few cases of SHML (<1%) involving the gastrointestinal system have been described in the literature. We report an unusual case of primary pancreatic SHML with infiltration of the process into peripancreatic, perinephric, and perisplenic adipose tissue, simulating malignancy.

scholarly journals DIAGNOSIS OF ROSAI-DORFMAN DISEASE BY FINE NEEDLE ASPIRATION CYTOLOGY- A STUDY OF ELEVEN CASES WITH EMPHASIS ON SITE

2020 ◽  
pp. 1-3
Author(s):  
Rinsha Surendranath ◽  
M Rajani
Keyword(s):  
Lymph Node ◽  
Lymph Nodes ◽  
Cervical Lymph Node ◽  
Age Distribution ◽  
Needle Aspiration ◽  
Cervical Region ◽  
Axillary Lymph ◽  
Diagnostic Significance ◽  
Massive Lymphadenopathy ◽  
Rosai Dorfman Disease

Rosai Dorfman Disease also called as Sinus Histiocytosis with Massive Lymphadenopathy is a benign proliferative disorder of histiocytes which typically affects lymph nodes of cervical region ,however extranodal sites are also being reported by many authors[1].FNAC is the investigation of choice as is it less invasive and more reliable.Aims :To study the various sites of involvement and diagnostic significance of FNAC along with the pattern of site and age distribution .We studied a series of 11 cases for a period of one year.Materials and methods: Eleven cases studied in the department of Pathology Govt. Siddhartha Medical College,Vijayawada.Material collected from Govt. General Hospital,Vijayawada.Results:The present study showed two extranodal,one axillary lymph node,one inguinal lymph node and seven cervical lymph node involment.Conclusion:Rosai- dorfman disease main clinical manifestion is cervical lymph node enlargement ,but other lymph nodes and extranodal site can also be involved.Most common age of presentation was between 20-40years

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